Search Results - "Weeks, J K"

Sensitization of human tumor cells to CPT-11 via adenoviral-mediated delivery of a rabbit liver carboxylesterase by WIERDL, Monika, MORTON, Christopher L, WEEKS, James K, DANKS, Mary K, HARRIS, Linda C, POTTER, Philip M

“…Irinotecan, 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) is activated by carboxylesterases (CE) to yield the potent topoisomerase…”
Get full text

Diffuse CNS Vasculopathy with Chronic Epstein-Barr Virus Infection in X-Linked Lymphoproliferative Disease by Weeks, J.K, Helton, K.J, Conley, M.E, Onciu, M, Khan, R.B

“…We report a patient with X-linked lymphoproliferative disease (XLP) who developed multiple central nervous system (CNS) manifestations of Epstein-Barr virus…”
Get full text

Three-dimensional applicator system for carcinoma of the uterine cervix by Weeks, K J, Montana, G S

“…Intracavitary dose prescription for cancer of the uterine cervix has been based on the use of plane orthogonal films. Computed tomography (CT) and magnetic…”
Get more information

An NMR-based metabonomic investigation of the toxic effects of 3-trifluoromethyl-aniline on the earthworm Eisenia veneta by WARNE, MARK, LENZ, E.M., OSBORN, D., WEEKS, J.M., NICHOLSON, J.K.

“…1H NMR spectra of earthworms Eisenia veneta treated with 3-trifluoromethyl-aniline in a 72-h contact filter paper test have been analysed using pattern…”
Get full text

The Compton backscattering process and radiotherapy by Weeks, K. J., Litvinenko, V. N., Madey, J. M. J.

“…Radiotherapy utilizes photons for treating cancer. Historically these photons have been produced by the bremsstrahlung process. In this paper we introduce…”
Get full text

In situ monitoring of parasitic growth on the quartz top plate during the MOVPE growth of GaAs/AlGaAs structures by Weeks, K.J., Irvine, S.J.C., Bland, S.W.

“…Work on the analysis by in situ monitoring using a 980nm laser reflectometer of parasitic deposition during MOVPE growth of GaAs/AlGaAs layers in an Aix-2400…”
Get full text

Method for determining photonuclear production of radioisotopes using high-energy electron beams by Weeks, K. J.

“…Linear accelerators can produce electrons at high power and energy. These electrons can be targeted at materials to produce radionuclides. Monte Carlo…”
Get full text

High-dose, hyperfractionated, accelerated radiotherapy using a concurrent boost for the treatment of nonsmall cell lung cancer: unusual toxicity and promising early results by King, S C, Acker, J C, Kussin, P S, Marks, L B, Weeks, K J, Leopold, K A

“…The treatment of nonsmall cell lung cancer (NSCLC) with conventional radiotherapy (RT) results in inadequate local tumor control and survival. We report…”
Get more information

In situ reflectance monitoring in MOVPE of a multiwafer reactor by Weeks, K.J., Irvine, S.J.C., Stafford, A., Jones, S., Bland, S., Joel, A.

“…A new design is presented that combines an interferometer and rotation monitor for in situ monitoring of variations in the growth process in Aixtron planetary…”
Get full text

Production of radioisotopes by direct electron activation by Weeks, K. J., O’Shea, P. G.

“…High-energy electrons bombarded on materials can induce radioactivity by either directly knocking out neutrons or by first converting a fraction of the…”
Get full text

Monte Carlo dose calculations for a new ovoid shield system for carcinoma of the uterine cervix by Weeks, K. J.

“…The dose distribution for an ovoid with a new tungsten shielding design was determined using Monte Carlo simulation. Standard Cesium-137 tube sources, tungsten…”
Get full text

3-dimensional optimization of multiple arcs for stereotactic radiosurgery by Weeks, K J, Marks, L, Ray, S K, Spencer, D P, Turner, D A, Friedman, A H

“…During linear accelerator-based radiosurgery, the physicians and physicists need to determine which combination of treatment arcs are "best" with regard to…”
Get more information

Characterization of gypsum attenuators for radiotherapy dose modification by Arora, V R, Weeks, K J

“…Gypsum has significant value as a compensator material for use with high energy x rays in radiation therapy. Compensator thickness may be calculated by using…”
Get more information

3-D dose-volume compensation using nonlinear least-squares regression technique by Weeks, K J, Sontag, M R

“…A method for external beam dose-volume optimization is presented. The Gauss-Marquardt nonlinear least-squares regression technique is applied to compensator…”
Get more information

Design of a plastic minicolpostat applicator with shields by Weeks, K J, Montana, G S, Bentel, G C

“…A plastic intracavitary applicator system for the treatment of cancer of the uterine cervix is described. This applicator has a minicolpostat and a mechanism…”
Get more information

Dose calculation and measurements for a CT compatible version of the Fletcher applicator by Weeks, K J, Dennett, J C

“…Experimental measurements in a water phantom were made for a new shielded plastic Fletcher applicator. A dose calculation algorithm which allows the…”
Get more information

Gypsum mixtures for compensator construction by Weeks, K J, Fraass, B A, Hutchins, K M

“…The characteristics and properties of a new material used for the fabrication of compensators are presented. This material is a special, refined gypsum. It…”
Get more information

Structural constraints affect the metabolism of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) by carboxylesterases by Wadkins, R M, Morton, C L, Weeks, J K, Oliver, L, Wierdl, M, Danks, M K, Potter, P M

“…7-Ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin [CPT-11 (irinotecan)] is a water-soluble camptothecin-derived prodrug that is activated by…”
Get more information

Clinical use of a concomitant boost technique using a gypsum compensator by Weeks, K J, Arora, V R, Leopold, K A, Light, K L, King, S C, Ray, S K, Sontag, M R, Smith, K D

“…To develop a clinical procedure to treat field within a field (concomitant boost) portals with a single compensated field. An ordinary manual cerrobend block…”
Get more information

Improvements in selective nuclear magnetic resonance excitation using nonlinear gradients by Weeks, K J, Gore, J C

“…The potential role of nonlinearities in the magnetic field gradient in magnetic resonance imaging for producing sharper boundaries for the excited spin slice…”
Get more information