Search Results - "Weeks, Amanda J."

Correlation of hypoxia PET tracer uptake with hypoxic radioresistance in cancer cells: PET biomarkers of resistance to stereotactic radiation therapy? by Chia, Kazumi, Paul, Rowena L., Weeks, Amanda J., Naeem, Marium, Mullen, Gregory E.D., Landau, David, Blower, Philip J.

“…The pO2 threshold of an ideal PET hypoxia tracer for radiotherapy planning in cancer would match those observed in clinically and biologically relevant…”
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Synthesis and biological evaluation of [18F]tetrafluoroborate: a PET imaging agent for thyroid disease and reporter gene imaging of the sodium/iodide symporter by Jauregui-Osoro, Maite, Sunassee, Kavitha, Weeks, Amanda J., Berry, David J., Paul, Rowena L., Cleij, Marcel, Banga, Jasvinder Paul, O’Doherty, Michael J., Marsden, Paul K., Clarke, Susan E. M., Ballinger, James R., Szanda, Istvan, Cheng, Sheue-Yann, Blower, Philip J.

“…Purpose The human sodium/iodide symporter (hNIS) is a well-established target in thyroid disease and reporter gene imaging using gamma emitters 123 I-iodide,…”
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p53-dependent radiobiological responses to internalised indium-111 in human cells by Weeks, Amanda J, Blower, Philip J, Lloyd, Daniel R

“…Abstract Introduction The p53 tumour suppressor protein plays a pivotal role in the response of mammalian cells to DNA damage. It regulates cell cycle…”
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Evaluation of [18F]-tetrafluoroborate as a potential PET imaging agent for the human sodium/iodide symporter in a new colon carcinoma cell line, HCT116, expressing hNIS by Weeks, Amanda J, Jauregui-Osoro, Maite, Cleij, Marcel, Blower, Julia E, Ballinger, James R, Blower, Philip J

“…PURPOSEAccumulation of iodide and other substrates via the human sodium/iodide symporter (hNIS) is fundamental to imaging and therapy of thyroid disease, hNIS…”
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Can PET hypoxia tracers predict radioresistance? by Chia, Kazumi, Weeks, Amanda J, Paul, Rowena L, Cleij, Marcel, Blower, Philip J

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Radiobiological effects of hypoxia-dependent uptake of 64Cu-ATSM: enhanced DNA damage and cytotoxicity in hypoxic cells by Weeks, Amanda J., Paul, Rowena L., Marsden, Paul K., Blower, Philip J., Lloyd, Daniel R.

“…Purpose Hypoxia occurs frequently in cancers and can lead to therapeutic resistance due to poor perfusion and loss of the oxygen enhancement effect. 64 Cu-ATSM…”
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