Search Results - "Wedmann, Rudolf"

Biosynthesis and Reactivity of Cysteine Persulfides in Signaling by Yadav, Pramod K, Martinov, Michael, Vitvitsky, Victor, Seravalli, Javier, Wedmann, Rudolf, Filipovic, Milos R, Banerjee, Ruma

“…Hydrogen sulfide (H2S) elicits pleiotropic physiological effects ranging from modulation of cardiovascular to CNS functions. A dominant method for transmission…”
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Assessment of H2S in vivo using the newly developed mitochondria-targeted mass spectrometry probe MitoA by Arndt, Sabine, Baeza-Garza, Carlos D., Logan, Angela, Rosa, Tiziana, Wedmann, Rudolf, Prime, Tracy A., Martin, Jack L., Saeb-Parsy, Kourosh, Krieg, Thomas, Filipovic, Milos R., Hartley, Richard C., Murphy, Michael P.

“…Hydrogen sulfide (H2S) is produced endogenously in vivo and has multiple effects on signaling pathways and cell function. Mitochondria can be both an H2S…”
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Improved tag-switch method reveals that thioredoxin acts as depersulfidase and controls the intracellular levels of protein persulfidation by Wedmann, Rudolf, Onderka, Constantin, Wei, Shengwei, Szijártó, István András, Miljkovic, Jan Lj, Mitrovic, Aleksandra, Lange, Mike, Savitsky, Sergey, Yadav, Pramod Kumar, Torregrossa, Roberta, Harrer, Ellen G, Harrer, Thomas, Ishii, Isao, Gollasch, Maik, Wood, Mark E, Galardon, Erwan, Xian, Ming, Whiteman, Matthew, Banerjee, Ruma, Filipovic, Milos R

“…Hydrogen sulfide (H 2 S) has emerged as a signalling molecule capable of regulating several important physiological functions such as blood pressure,…”
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PP15 - Perthionitrite – does it have any biological relevance? Full (bio)chemical characterization of the crystalline –SSNO salt by Wedmann, Rudolf, Filipovic, Milos R.

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Perthionitrite – does it have any biological relevance? Full (bio)chemical characterization of the crystalline –SSNO salt by Wedmann, Rudolf, Filipovic, Milos R.

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Working with “H2S”: Facts and apparent artifacts by Wedmann, Rudolf, Bertlein, Sarah, Macinkovic, Igor, Böltz, Sebastian, Miljkovic, Jan Lj, Muñoz, Luis E., Herrmann, Martin, Filipovic, Milos R.

“…•Polysulfides and metal ions present in H2S solutions reduce protein disulfides.•High H2S concentrations lead to the inhibition of cell respiration and ΔΨm…”
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Does Perthionitrite (SSNO–) Account for Sustained Bioactivity of NO? A (Bio)chemical Characterization by Wedmann, Rudolf, Zahl, Achim, Shubina, Tatyana E, Dürr, Maximilian, Heinemann, Frank W, Bugenhagen, Bernhard Eberhard Christian, Burger, Peter, Ivanovic-Burmazovic, Ivana, Filipovic, Milos R

“…Hydrogen sulfide (H2S) and nitric oxide (NO) are important signaling molecules that regulate several physiological functions. Understanding the chemistry…”
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Physiological significance of persulfide generation by the transsulfuration pathway by Yadav, Pramod Kumar, Martinov, Michael, Vitvitsky, Victor, Seravalli, Javier, Wedmann, Rudolf, Filipovic, Milos R, Banerjee, Ruma

“…Abstract only In mammalian cells, cystathionine β‐synthase (CBS), cystathionine γ‐lyase (CSE) and merceptopyruvate sulfurtransferase (MST) catalyze H 2 S…”
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Insights into the mechanism of the reaction between hydrogen sulfide and peroxynitrite by Cuevasanta, Ernesto, Zeida, Ari, Carballal, Sebastián, Wedmann, Rudolf, Morzan, Uriel N., Trujillo, Madia, Radi, Rafael, Estrin, Darío A., Filipovic, Milos R., Alvarez, Beatriz

“…Hydrogen sulfide and peroxynitrite are endogenously generated molecules that participate in biologically relevant pathways. A revision of the kinetic features…”
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Synthesis and Pharmacological Evaluation of Novel Adenine–Hydrogen Sulfide Slow Release Hybrids Designed as Multitarget Cardioprotective Agents by Lougiakis, Nikolaos, Papapetropoulos, Andreas, Gikas, Evangelos, Toumpas, Spyridon, Efentakis, Panagiotis, Wedmann, Rudolf, Zoga, Anastasia, Zhou, Zhongmin, Iliodromitis, Efstathios K, Skaltsounis, Alexios-Leandros, Filipovic, Milos R, Pouli, Nicole, Marakos, Panagiotis, Andreadou, Ioanna

“…This work deals with the design, synthesis, and evaluation of the cardioprotective properties of a number of novel hybrid compounds combining the adenine…”
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Nitrosopersulfide (SSNO−) decomposes in the presence of sulfide, cyanide or glutathione to give HSNO/SNO−: consequences for the assumed role in cell signalling by Wedmann, Rudolf, Ivanovic-Burmazovic, Ivana, Filipovic, Milos R.

“…The emergence of hydrogen sulfide (H2S) as a new signalling molecule able to control vasodilation, neurotransmission and immune response, prompted questions…”
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PSS307 - We Have Come a Long Way with Mn Porphyrins: from Superoxide Dismutation to H2O2-Driven Pathways by Tovmasyan, Artak, Weitner, Tin, Jaramillo, Melba, Wedmann, Rudolf, Roberts, Emily R.H., Leong, Kam W., Filipovic, Milos, Ivanovic-Burmazovic, Ivana, Benov, Ludmil, Tome, Margaret E., Batinic-Haberle, Ines

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We Have Come a Long Way with Mn Porphyrins: from Superoxide Dismutation to H2O2-Driven Pathways by Tovmasyan, Artak, Weitner, Tin, Jaramillo, Melba, Wedmann, Rudolf, Roberts, Emily R.H., Leong, Kam W., Filipovic, Milos, Ivanovic-Burmazovic, Ivana, Benov, Ludmil, Tome, Margaret E., Batinic-Haberle, Ines

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Improved tag-switch method reveals that thioredoxin acts as depersulfidase and controls the intracellular levels of protein persulfidation† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc04818d by Wedmann, Rudolf, Onderka, Constantin, Wei, Shengwei, Szijártó, István András, Miljkovic, Jan Lj, Mitrovic, Aleksandra, Lange, Mike, Savitsky, Sergey, Yadav, Pramod Kumar, Torregrossa, Roberta, Harrer, Ellen G., Harrer, Thomas, Ishii, Isao, Gollasch, Maik, Wood, Mark E., Galardon, Erwan, Xian, Ming, Whiteman, Matthew, Banerjee, Ruma, Filipovic, Milos R.

“…H 2 S signals via protein persulfidation. To be regulatory the modification will have to be reversible. Using a new method for persulfide detection, we…”
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Assessment of H 2 S in vivo using the newly developed mitochondria-targeted mass spectrometry probe MitoA by Arndt, Sabine, Baeza-Garza, Carlos D, Logan, Angela, Rosa, Tiziana, Wedmann, Rudolf, Prime, Tracy A, Martin, Jack L, Saeb-Parsy, Kourosh, Krieg, Thomas, Filipovic, Milos R, Hartley, Richard C, Murphy, Michael P

“…Hydrogen sulfide (H S) is produced endogenously and has multiple effects on signaling pathways and cell function. Mitochondria can be both an H S source and…”
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