Search Results - "Wedel, N."

Prolene Hernia System, Lichtenstein mesh and plug-and-patch for primary inguinal hernia repair: 3-year outcome of a prospective randomised controlled trial: The BOOP study: Bi-layer and connector, On-lay, and On-lay with Plug for inguinal hernia repair by Dalenbäck, J., Andersson, C., Anesten, B., Björck, S., Eklund, S., Magnusson, O., Rimbäck, G., Stenquist, B., Wedel, N.

“…Background Dissection requirements differ between various methods for inguinal hernia repair, which may affect operation times, pain response and possibly…”
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Treatment of relapsed or refractory acute myeloid leukemia with humanized anti-CD33 monoclonal antibody HuM195 by FELDMAN, E, KALAYCIO, M, LEVITT, D, WEDEL, N, WEINER, G, FRANKEL, S, SCHULMAN, P, SCHWARTZBERG, L, JURCIC, J, VELEZ-GARCIA, E, SEITER, K, SCHEINBERG, D

“…HuM195 is a humanized, unconjugated, anti-CD33 monoclonal antibody. Fifty adult patients with relapsed or refractory AML were randomized to receive HuM195 at a…”
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Preliminary evaluation of recombinant amino-terminal fragment of human bactericidal/permeability-increasing protein in children with severe meningococcal sepsis by Giroir, B P, Quint, P A, Barton, P, Kirsch, E A, Kitchen, L, Goldstein, B, Nelson, B J, Wedel, N J, Carroll, S F, Scannon, P J

“…Meningococcal sepsis remains an important cause of morbidity and mortality. We hypothesised that children with severe meningococcaemia might benefit from…”
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Prospective follow-up after ambulatory plain midline excision of pilonidal sinus and primary suture under local anaesthesia - efficient, sufficient, and persistent by Dalenbäck, J., Magnusson, O., Wedel, N., Rimbäck, G.

“…Objective  Optimal surgical treatment for chronic pilonidal sinus (PS) disease should be easy and efficient. The purpose of this study was to establish the…”
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Inhibition of Endotoxin-Induced Cytokine Release and Neutrophil Activation in Humans by Use of Recombinant Bactericidal/Permeability-Increasing Protein by von der Möhlen, Marijke A. M., Kimmings, A. Nikola, Wedel, Nancy I., Mevissen, Marcel L. C. M., Jansen, Jaap, Friedmann, Nadav, Lorenz, Todd J., Nelson, Betty J., White, Mark L., Bauer, Robert, Hack, C. Erik, Eerenberg, Anke J. M., van Deventer, Sander J. H.

“…To investigate the effects of a recombinant endotoxin-binding protein, bactericidal/permeabilityincreasing protein (rBPI23), on cytokine release and neutrophil…”
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Phase I trial of Hum291, a humanized anti-CD3 antibody, in patients receiving renal allografts from living donors by NORMAN, Douglas J, VINCENTI, Flavio, DE MATTOS, Angelo M, BARRY, John M, LEVITT, Daniel J, WEDEL, Nancy I, MAIA, Mauricio, LIGHT, Susan E

“…HuM291 is a humanized anti-CD3 monoclonal antibody engineered to reduce binding to Fcgamma receptors and complement fixation. HuM291 has a long serum half-life…”
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Inhibition of Endotoxin-Induced Activation of the Coagulation and Fibrinolytic Pathways Using a Recombinant Endotoxin-Binding Protein (rBPI23) by Möhlen, Marijke A.M. von der, Deventer, Sander J.H. van, Levi, Marcel, Ende, Bram van den, Wedel, Nancy I., Nelson, Betty J., Friedmann, Nadav, Cate, Jan Wouter ten

“…A recombinant endotoxin-neutralizing protein, rBPI23, was shown to partially prevent endotoxin-induced activation of the fibrinolytic and coagulation systems…”
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Therapy of patients with malignant melanoma using a monoclonal antimelanoma antibody-ricin A chain immunotoxin by SPITLER, L. E, DEL RIO, M, KAWAHATA, R. T, STOUDEMIRE, J. B, FRADKIN, L. B, BAUTISTA, E. E, SCANNON, P. J, KHENTIGAN, A, WEDEL, N. I, BROPHY, N. A, MILLER, L. L, HARKONEN, W. S, ROSENDORF, L. L, LEE, H. M, MISCHAK, R. P

“…We conducted a trial of a murine monoclonal antimelanoma antibody-ricin A chain immunotoxin (XOMAZYME-MEL) in 22 patients with metastatic malignant melanoma…”
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Pharmacokinetics of a Recombinant Modified Amino Terminal Fragment of Bactericidal/Permeability-Increasing Protein (rBPI21) in Healthy Volunteers by Bauer, Robert J., Wedel, Nancy, Havrilla, Nancy, White, Mark, Cohen, Albert, Carroll, Stephen F.

“…Phase I pharmacokinetic and safety studies were conducted in healthy volunteers with rBPI21, a recombinant protein derived from the amino terminal domain of…”
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Observations using antiendotoxin antibody (E5) as adjuvant therapy in humans with suspected, serious, gram-negative sepsis by Greenberg, R N, Wilson, K M, Kunz, A Y, Wedel, N I, Gorelick, K J

“…To evaluate the safety and efficacy of E5 (Xomen-E5), a murine monoclonal immunoglobulin M antibody, in reducing mortality in patients with serious…”
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Transition time to full nipple feeding for premature infants with a history of lung disease by Pridham, K, Brown, R, Sondel, S, Green, C, Wedel, N Y, Lai, H C

“…To (a) explore the contribution of infant, environmental, and historical factors to the number of days from initiation to achievement of full nipple feeding…”
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Phase III Randomized Multicenter Study of a Humanized Anti-CD33 Monoclonal Antibody, Lintuzumab, in Combination With Chemotherapy, Versus Chemotherapy Alone in Patients With Refractory or First-Relapsed Acute Myeloid Leukemia by FELDMAN, Eric J, BRANDWEIN, Joseph, JURCIC, Joseph C, BROWN, Randy, EHMANN, W. Christopher, SCHULMAN, Philip, FRANKEL, Stanley R, DE ANGELO, Daniel, SCHEINBERG, David, STONE, Richard, KALAYCIO, Matt, MOORE, Joseph, O'CONNOR, Julie, WEDEL, Nancy, ROBOZ, Gail J, MILLER, Carole, CHOPRA, Raj

“…Lintuzumab (HuM195) is an unconjugated humanized murine monoclonal antibody directed against the cell surface myelomonocytic differentiation antigen CD33. In…”
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Phase I/II study of murine monoclonal antibody-ricin A chain (XOMAZYME-Mel) immunoconjugate plus cyclosporine A in patients with metastatic melanoma by Selvaggi, K, Saria, E A, Schwartz, R, Vlock, D R, Ackerman, S, Wedel, N, Kirkwood, J M, Jones, H, Ernstoff, M S

“…XOMAZYME-Mel (XMMME-001-RTA) is an immunoconjugate comprised of ricin A chain conjugated to a murine monoclonal antibody directed against high molecular weight…”
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Nucleotide sequence of cDNAs encoding the entire precursor polypeptide for thioredoxin m from spinach chloroplasts by Wedel, N. (Ludwig-Maximilians-Universitaet, Muenchen (Germany). Botanisches Inst.), Clausmeyer, S, Herrmann, R.G, Gardet-Salvi, L, Schuermann, P

“…Using the expression vector lambda gt11 and immunochemical detection, six cDNA clones that encode the entire precursor polypeptides for spinach thioredoxin m…”
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Evolutionary Conserved Light Regulation of Calvin Cycle Activity by NADPH-Mediated Reversible Phosphoribulokinase/CP12/Glyceraldehyde-3-Phosphate Dehydrogenase Complex Dissociation by Wedel, Norbert, Soll, Jurgen

“…For higher plant chloroplasts, two key enzymes of the Calvin cycle, phosphoribulokinase (EC 2.7.1.19) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH, EC…”
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Diatom Plastids Possess a Phosphoribulokinase with an Altered Regulation and No Oxidative Pentose Phosphate Pathway by Michels, Andreas K, Wedel, Norbert, Kroth, Peter G

“…The chloroplast enzyme phosphoribulokinase (PRK; EC 2.7.1.19) is part of the Calvin cycle (reductive pentose phosphate pathway) responsible for CO₂ fixation in…”
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The Small Protein CP12:  A Protein Linker for Supramolecular Complex Assembly by Graciet, Emmanuelle, Gans, Pierre, Wedel, Norbert, Lebreton, Sandrine, Camadro, Jean-Michel, Gontero, Brigitte

“…CP12 is an 8.5-kDa nuclear-encoded chloroplast protein, isolated from higher plants. It forms part of a core complex of two dimers of phosphoribulokinase…”
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Regulation of photosynthetic GAPDH dissected by mutants by Sparla, F, Zaffagnini, M, Wedel, N, Scheibe, R, Pupillo, P, Trost, P

“…Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) of higher plants catalyzes an NADPH-consuming reaction, which is part of the Calvin cycle. This reaction is…”
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Prolene Hernia System, Lichtenstein mesh and plug-and-patch for primary inguinal hernia repair: 3-year outcome of a prospective randomised controlled trial by Dalenbäck, Jan, Andersson, C, Anesten, B., Björck, S, Eklund, S., Magnusson, Olle, Rimbäck, Gunnar, Stenquist, B., Wedel, Nancy

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Recombinant endotoxin-binding protein (rBPI23) attenuates endotoxin-induced circulatory changes in humans by de Winter, R J, von der Möhlen, M A, van Lieshout, H, Wedel, N, Nelson, B, Friedmann, N, Delemarre, B J, van Deventer, S J

“…In the present study the protective effect of a recombinant endotoxin-binding protein rBPI23 on the circulatory changes in experimental endotoxemia in humans…”
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