Search Results - "Wechselberger, Rainer W."

Structural Dynamics in the Activation of Epac by Harper, Shannon M., Wienk, Hans, Wechselberger, Rainer W., Bos, Johannes L., Boelens, Rolf, Rehmann, Holger

“…Epac1 is a cAMP-responsive exchange factor for the small G-protein Rap. It consists of a regulatory region containing a cyclic nucleotide binding (CNB) domain…”
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Structural Properties of the Promiscuous VP16 Activation Domain by Jonker, Hendrik R. A, Wechselberger, Rainer W, Boelens, Rolf, Folkers, Gert E, Kaptein, Rob

“…Herpes simplex virion protein 16 (VP16) contains two strong activation regions that can independently and cooperatively activate transcription in vivo. We have…”
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Gradual phosphorylation regulates PC4 coactivator function by Jonker, Hendrik R. A., Wechselberger, Rainer W., Pinkse, Martijn, Kaptein, Robert, Folkers, Gert E.

“…The unstructured N‐terminal domain of the transcriptional cofactor PC4 contains multiple phosphorylation sites that regulate activity. The phosphorylation…”
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The Tandem Zinc-Finger Region of Human ZHX Adopts a Novel C2H2 Zinc Finger Structure with a C-Terminal Extension by Wienk, Hans, Lammers, Ivonne, Hotze, Anna, Wu, Jin, Wechselberger, Rainer W, Owens, Ray, Stammers, David K, Stuart, David, Kaptein, Robert, Folkers, Gert E

“…Binding of the nuclear factor-Y complex (NF-Y) to the inverted CCAAT-box interferes with transcription activation through nucleosome reorganization. The three…”
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The Intrinsically Unstructured Domain of PC4 Modulates the Activity of the Structured Core through Inter- and Intramolecular Interactions by Jonker, Hendrik R. A, Wechselberger, Rainer W, Boelens, Rolf, Kaptein, Rob, Folkers, Gert E

“…Proteins frequently contain unstructured regions apart from a functionally important and well-conserved structured domain. Functional and structural aspects…”
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Lack of Negative Charge in the E46Q Mutant of Photoactive Yellow Protein Prevents Partial Unfolding of the Blue-Shifted Intermediate by Derix, Nocky M, Wechselberger, Rainer W, van der Horst, Michael A, Hellingwerf, Klaas J, Boelens, Rolf, Kaptein, Rob, van Nuland, Nico A. J

“…The long-lived light-induced intermediate (pB) of the E46Q mutant (glutamic acid is replaced by glutamine at position 46) of photoactive yellow protein (PYP)…”
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Structure, Dynamics, and Insertion of a Chloroplast Targeting Peptide in Mixed Micelles by Wienk, Hans L. J, Wechselberger, Rainer W, Czisch, Michael, de Kruijff, Ben

“…Nuclear-encoded, chloroplast-destined proteins are synthesized with transit sequences that contain all information to get them inside the organelle. Different…”
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An alternate conformation of the hyperthermostable HU protein from Thermotoga maritima has unexpectedly high flexibility by Durney, Michael A, Wechselberger, Rainer W, Kalodimos, Charalampos G, Kaptein, Robert, Vorgias, Constantinos E, Boelens, Rolf

“…The homodimeric HU protein from the hyperthermophile Thermotoga maritima (HU Tmar) is a model system which can yield insights into the molecular determinants…”
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Glycolipid transfer protein: clear structure and activity, but enigmatic function by Neumann, Sylvia, Opacić, Milena, Wechselberger, Rainer W, Sprong, Hein, Egmond, Maarten R

“…In conclusion, we have found that the efficiency of uptake of glycolipid by GLTP depends on the mole fraction of the glycolipid in the outer leaflet of…”
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Letter to the Editor: 1H, 13C and 15N backbone resonance assignment of the arsenate reductase from Staphylococcus aureus in its reduced state by Jacobs, Doris M, Messens, Joris, Wechselberger, Rainer W, Brosens, Elke, Willem, Rudolph, Wyns, Lode, Martins, José C

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