Search Results - "Wechselberger, R"

Solution structure and DNA-binding properties of the C-terminal domain of UvrC from E.coli by Singh, S, Folkers, G. E., Bonvin, A. M. J. J., Boelens, R, Wechselberger, R, Niztayev, A, Kaptein, R

“…The C‐terminal domain of the UvrC protein (UvrC CTD) is essential for 5′ incision in the prokaryotic nucleotide excision repair process. We have determined the…”
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Slow conformational dynamics of an endonuclease persist in its complex with its natural protein inhibitor by WHITTAKER, SARA B.-M., CZISCH, MICHAEL, WECHSELBERGER, RAINER, KAPTEIN, ROBERT, HEMMINGS, ANDREW M., JAMES, RICHARD, KLEANTHOUS, COLIN, MOORE, GEOFFREY R.

“…The bacterial toxin colicin E9 is secreted by producing Escherichia coli cells with its 9.5 kDa inhibitor protein Im9 bound tightly to its 14.5 kDa C-terminal…”
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Structure, Dynamics, and Insertion of a Chloroplast Targeting Peptide in Mixed Micelles by Wienk, Hans L. J, Wechselberger, Rainer W, Czisch, Michael, de Kruijff, Ben

“…Nuclear-encoded, chloroplast-destined proteins are synthesized with transit sequences that contain all information to get them inside the organelle. Different…”
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Solution Structure of a Chemosensory Protein from the Desert Locust Schistocerca gregaria by Tomaselli, Simona, Crescenzi, Orlando, Sanfelice, Domenico, AB, Eiso, Wechselberger, Rainer, Angeli, Sergio, Scaloni, Andrea, Boelens, Rolf, Tancredi, Teodorico, Pelosi, Paolo, Picone, Delia

“…Chemical stimuli, generally constituted by small volatile organic molecules, are extremely important for the survival of different insect species. In the…”
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Determination of a complete set of coupling constants in 13C-labeled oligonucleotides by Schwalbe, H, Marino, J P, King, G C, Wechselberger, R, Bermel, W, Griesinger, C

“…Three experiments are introduced to determine a complete set of coupling constants in RNA oligomers. In the HCCH-E.COSY experiment, the vicinal proton-proton…”
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Plasticity in protein-DNA recognition: lac repressor interacts with its natural operator O1 through alternative conformations of its DNA-binding domain by Kalodimos, Charalampos G., Bonvin, Alexandre M.J.J, Salinas, Roberto K., Wechselberger, Rainer, Boelens, Rolf, Kaptein, Robert

“…The lac repressor–operator system is a model system for understanding protein–DNA interactions and allosteric mechanisms in gene regulation. Despite the wealth…”
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Segment TM7 from the cytoplasmic hemi-channel from VO-H+-V-ATPase includes a flexible region that has a potential role in proton translocation by Duarte, Afonso M.S., de Jong, Edwin R., Wechselberger, Rainer, van Mierlo, Carlo P.M., Hemminga, Marcus A.

“…A 900-MHz NMR study is reported of peptide sMTM7 that mimics the cytoplasmic proton hemi-channel domain of the seventh transmembrane segment (TM7) from subunit…”
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GM3, GM2 and GM1 mimics designed for biosensing: chemoenzymatic synthesis, target affinities and 900 MHz NMR analysis by Pukin, Aliaksei V., Weijers, Carel A.G.M., van Lagen, Barend, Wechselberger, Rainer, Sun, Bin, Gilbert, Michel, Karwaski, Marie-France, Florack, Dion E.A., Jacobs, Bart C., Tio-Gillen, Anne P., van Belkum, Alex, Endtz, Hubert P., Visser, Gerben M., Zuilhof, Han

“…Undec-10-enyl, undec-10-ynyl and 11-azidoundecyl glycoside analogues corresponding to the oligosaccharides of human gangliosides GM3, GM2 and GM1 were…”
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Structure of the fMet-tRNA(fMet)-binding domain of B. stearothermophilus initiation factor IF2 by Meunier, S, Spurio, R, Czisch, M, Wechselberger, R, Guenneugues, M, Gualerzi, C O, Boelens, R

“…The three-dimensional structure of the fMet-tRNA(fMet) -binding domain of translation initiation factor IF2 from Bacillus stearothermophilus has been…”
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Structural Characterization of the PIT-1/ETS-1 Interaction: PIT-1 Phosphorylation Regulates PIT-1/ETS-1 Binding by Augustijn, Kevin D., Duval, Dawn L., Wechselberger, Rainer, Kaptein, Rob, Gutierrez-Hartmann, Arthur, van der Vliet, Peter C.

“…The POU-domain transcription factor Pit-1 and Ets-1, a member of the ETS family of transcription factors, can associate in solution and synergistically…”
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Analysis of Protein−Carbohydrate Interaction at the Lower Size Limit of the Protein Part (15-Mer Peptide) by NMR Spectroscopy, Electrospray Ionization Mass Spectrometry, and Molecular Modeling by Siebert, Hans-Christian, Lü, Shan-Yun, Frank, Martin, Kramer, Jasper, Wechselberger, Rainer, Joosten, John, André, Sabine, Rittenhouse-Olson, Kate, Roy, René, von der Lieth, Claus-Wilhelm, Kaptein, Robert, Vliegenthart, Johannes F. G, Heck, Albert J. R, Gabius, Hans-Joachim

“…Structural analysis of minimally sized lectins will offer insights into fundamentals of intermolecular recognition and potential for biomedical applications…”
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Hinge-helix formation and DNA bending in various lac repressor-operator complexes by Spronk, Christian A. E. M., Folkers, Gert E., Noordman, Anne-Marie G. W., Wechselberger, Rainer, van den Brink, Nienke, Boelens, Rolf, Kaptein, Robert

“…The hinge‐region of the lac repressor plays an important role in the models for induction and DNA looping in the lac operon. When lac repressor is bound to a…”
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Structure of the S4 and S4-S5 loop region of a voltage-gated potassium channel by Haris, P I, Wechselberger, R, Czisch, M

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Structure of the fMet-tRNA super(fMet)-binding domain of B. stearothermophilus initiation factor IF2 by Meunier, S, Spurio, R, Czisch, M, Wechselberger, R, Guenneugues, M, Gualerzi, C, Boelens, R

“…The three-dimensional structure of the fMet-tRNA super(fMet) - binding domain of translation initiation factor IF2 from Bacillus stearothermophilus has been…”
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Refined solution structure of the dimeric N-terminal HHCC domain of HIV-2 integrase by Eijkelenboom, A P, van den Ent, F M, Wechselberger, R, Plasterk, R H, Kaptein, R, Boelens, R

“…The solution structure of the dimeric N-terminal domain of HIV-2 integrase (residues 1-55, named IN(1-55)) has been determined using NMR spectroscopy. The…”
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Identification of the Single-stranded DNA Binding Surface of the Transcriptional Coactivator PC4 by NMR by Werten, Sebastiaan, Wechselberger, Rainer, Boelens, Rolf, van der Vliet, Peter C., Kaptein, Robert

“…The C-terminal domain of the eukaryotic transcriptional cofactor PC4 (PC4CTD) is known to bind with nanomolar affinity to single-stranded (ss)DNA. Here, NMR is…”
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1H, 13C and 15N backbone resonance assignment of the arsenate reductase from Staphylococcus aureus in its reduced state by Jacobs, D M, Messens, J, Wechselberger, R W, Brosens, E, Willem, R, Wyns, L, Martin, J C

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Structural Properties of the Promiscuous VP16 Activation Domain by Jonker, Hendrik R. A, Wechselberger, Rainer W, Boelens, Rolf, Folkers, Gert E, Kaptein, Rob

“…Herpes simplex virion protein 16 (VP16) contains two strong activation regions that can independently and cooperatively activate transcription in vivo. We have…”
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Gradual phosphorylation regulates PC4 coactivator function by Jonker, Hendrik R. A., Wechselberger, Rainer W., Pinkse, Martijn, Kaptein, Robert, Folkers, Gert E.

“…The unstructured N‐terminal domain of the transcriptional cofactor PC4 contains multiple phosphorylation sites that regulate activity. The phosphorylation…”
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The Intrinsically Unstructured Domain of PC4 Modulates the Activity of the Structured Core through Inter- and Intramolecular Interactions by Jonker, Hendrik R. A, Wechselberger, Rainer W, Boelens, Rolf, Kaptein, Rob, Folkers, Gert E

“…Proteins frequently contain unstructured regions apart from a functionally important and well-conserved structured domain. Functional and structural aspects…”
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