Search Results - "Webster, G. J."

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    Dysregulation of RNA splicing in early non-alcoholic fatty liver disease through hepatocellular carcinoma by Webster, Nicholas J. G., Kumar, Deepak, Wu, Panyisha

    Published in Scientific reports (30-01-2024)
    “…While changes in RNA splicing have been extensively studied in hepatocellular carcinoma (HCC), no studies have systematically investigated changes in RNA…”
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    Journal Article
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    Splicing factor SRSF3 is crucial for hepatocyte differentiation and metabolic function by Sen, Supriya, Jumaa, Hassan, Webster, Nicholas J. G.

    Published in Nature communications (01-01-2013)
    “…SR family RNA binding proteins regulate splicing of nascent RNAs in vitro but their physiological role in vivo is largely unexplored, as genetic deletion of…”
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    Mitochondrial Dysfunction in Obesity and Reproduction by Das, Manasi, Sauceda, Consuelo, Webster, Nicholas J G

    Published in Endocrinology (Philadelphia) (01-01-2021)
    “…Abstract Mounting evidence suggests a role for mitochondrial dysfunction in the pathogenesis of many diseases, including type 2 diabetes, aging, and ovarian…”
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    hnRNP A1 and hnRNP F modulate the alternative splicing of exon 11 of the insulin receptor gene by Talukdar, Indrani, Sen, Supriya, Urbano, Rodolfo, Thompson, James, Yates, 3rd, John R, Webster, Nicholas J G

    Published in PloS one (23-11-2011)
    “…Exon 11 of the insulin receptor gene (INSR) is alternatively spliced in a developmentally and tissue-specific manner. Linker scanning mutations in a 5' GA-rich…”
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    SRp20 and CUG-BP1 Modulate Insulin Receptor Exon 11 Alternative Splicing by Sen, Supriya, Talukdar, Indrani, Webster, Nicholas J. G.

    Published in Molecular and Cellular Biology (01-02-2009)
    “…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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    A Novel Gonadotropin-Releasing Hormone 1 (Gnrh1) Enhancer-Derived Noncoding RNA Regulates Gnrh1 Gene Expression in GnRH Neuronal Cell Models by Huang, Polly P, Brusman, Liza E, Iyer, Anita K, Webster, Nicholas J G, Mellon, Pamela L

    Published in PloS one (07-07-2016)
    “…Gonadotropin-releasing hormone (GnRH), a neuropeptide released from a small population of neurons in the hypothalamus, is the central mediator of the…”
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    Cyclic AMP concentrations in dendritic cells induce and regulate Th2 immunity and allergic asthma by Lee, Jihyung, Kim, Tae Hoon, Murray, Fiona, Li, Xiangli, Choi, Sara S., Broide, David H., Corr, Maripat, Lee, Jongdae, Webster, Nicholas J. G., Insel, Paul A., Raz, Eyal

    “…Significance Allergic asthma is characterized by Th2 type inflammation, leading to airway hyperresponsiveness and remodeling. However, the mechanisms by which…”
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    Time-restricted feeding normalizes hyperinsulinemia to inhibit breast cancer in obese postmenopausal mouse models by Das, Manasi, Ellies, Lesley G., Kumar, Deepak, Sauceda, Consuelo, Oberg, Alexis, Gross, Emilie, Mandt, Tyler, Newton, Isabel G., Kaur, Mehak, Sears, Dorothy D., Webster, Nicholas J. G.

    Published in Nature communications (25-01-2021)
    “…Accumulating evidence indicates that obesity with its associated metabolic dysregulation, including hyperinsulinemia and aberrant circadian rhythms, increases…”
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    Interaction of musleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing by Paul, Sharan, Dansithong, Warunee, Kim, Dongho, Rossi, John, Webster, Nicholas JG, Comai, Lucio, Reddy, Sita

    Published in The EMBO journal (20-09-2006)
    “…In myotonic dystrophy (DM1), both inactivation of muscleblind proteins and increased levels of CUG‐BP1 are reported. These events have been shown to contribute…”
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    Alternative RNA Splicing in Fatty Liver Disease by Wu, Panyisha, Zhang, Moya, Webster, Nicholas J G

    Published in Frontiers in endocrinology (Lausanne) (26-02-2021)
    “…Alternative RNA splicing is a process by which introns are removed and exons are assembled to construct different RNA transcript isoforms from a single…”
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    Obesity, cancer risk, and time-restricted eating by Das, Manasi, Webster, Nicholas J. G.

    Published in Cancer and metastasis reviews (01-09-2022)
    “…Obesity and the associated metabolic syndrome is considered a pandemic whose prevalence is steadily increasing in many countries worldwide. It is a complex,…”
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    Alternative RNA Splicing in the Pathogenesis of Liver Disease by Webster, Nicholas J G

    Published in Frontiers in endocrinology (Lausanne) (21-06-2017)
    “…Non-alcoholic fatty liver disease (NAFLD) is becoming increasingly prevalent due to the worldwide obesity epidemic and currently affects one-third of adults or…”
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    Review article: autoimmune pancreatitis – management of an emerging disease by Kalaitzakis, E., Webster, G. J. M.

    Published in Alimentary pharmacology & therapeutics (01-02-2011)
    “…Aliment Pharmacol Ther 2011; 33: 291–303 Summary Background  Autoimmune pancreatitis is a steroid‐responsive inflammatory pancreatic disease considered to be…”
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    Dry electrodes for electrocardiography by Meziane, N, Webster, J G, Attari, M, Nimunkar, A J

    Published in Physiological measurement (01-09-2013)
    “…Patient biopotentials are usually measured with conventional disposable Ag/AgCl electrodes. These electrodes provide excellent signal quality but are…”
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    Small molecule activators of the Trk receptors for neuroprotection by Webster, Nicholas J G, Pirrung, Michael C

    Published in BMC neuroscience (03-12-2008)
    “…The neurotrophin signaling network is critical to the development and survival of many neuronal populations. Especially sensitive to imbalances in the…”
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    Hepatocyte Deletion of IGF2 Prevents DNA Damage and Tumor Formation in Hepatocellular Carcinoma by Kumar, Deepak, Das, Manasi, Oberg, Alexis, Sahoo, Debashis, Wu, Panyisha, Sauceda, Consuelo, Jih, Lily, Ellies, Lesley G., Langiewicz, Magda T., Sen, Supriya, Webster, Nicholas J. G.

    Published in Advanced science (01-07-2022)
    “…Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Serine‐arginine rich splicing factor 3 (SRSF3) plays a critical role in hepatocyte…”
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