Search Results - "Webster, G J"
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1
International Consensus Guidance Statement on the Management and Treatment of IgG4‐Related Disease
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-07-2015)Get full text
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2
Dysregulation of RNA splicing in early non-alcoholic fatty liver disease through hepatocellular carcinoma
Published in Scientific reports (30-01-2024)“…While changes in RNA splicing have been extensively studied in hepatocellular carcinoma (HCC), no studies have systematically investigated changes in RNA…”
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Splicing factor SRSF3 is crucial for hepatocyte differentiation and metabolic function
Published in Nature communications (01-01-2013)“…SR family RNA binding proteins regulate splicing of nascent RNAs in vitro but their physiological role in vivo is largely unexplored, as genetic deletion of…”
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4
Mitochondrial Dysfunction in Obesity and Reproduction
Published in Endocrinology (Philadelphia) (01-01-2021)“…Abstract Mounting evidence suggests a role for mitochondrial dysfunction in the pathogenesis of many diseases, including type 2 diabetes, aging, and ovarian…”
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hnRNP A1 and hnRNP F modulate the alternative splicing of exon 11 of the insulin receptor gene
Published in PloS one (23-11-2011)“…Exon 11 of the insulin receptor gene (INSR) is alternatively spliced in a developmentally and tissue-specific manner. Linker scanning mutations in a 5' GA-rich…”
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SRp20 and CUG-BP1 Modulate Insulin Receptor Exon 11 Alternative Splicing
Published in Molecular and Cellular Biology (01-02-2009)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A Novel Gonadotropin-Releasing Hormone 1 (Gnrh1) Enhancer-Derived Noncoding RNA Regulates Gnrh1 Gene Expression in GnRH Neuronal Cell Models
Published in PloS one (07-07-2016)“…Gonadotropin-releasing hormone (GnRH), a neuropeptide released from a small population of neurons in the hypothalamus, is the central mediator of the…”
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Cyclic AMP concentrations in dendritic cells induce and regulate Th2 immunity and allergic asthma
Published in Proceedings of the National Academy of Sciences - PNAS (03-02-2015)“…Significance Allergic asthma is characterized by Th2 type inflammation, leading to airway hyperresponsiveness and remodeling. However, the mechanisms by which…”
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Long-term exposure to house dust mites accelerates lung cancer development in mice
Published in Journal of experimental & clinical cancer research (21-01-2023)“…Individuals with certain chronic inflammatory lung diseases have a higher risk of developing lung cancer (LC). However, the underlying mechanisms remain…”
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Chromogranin A regulates vesicle storage and mitochondrial dynamics to influence insulin secretion
Published in Cell and tissue research (01-06-2017)“…Chromogranin A (CgA) is a prohormone and a granulogenic factor that regulates secretory pathways in neuroendocrine tissues. In β-cells of the endocrine…”
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Time-restricted feeding normalizes hyperinsulinemia to inhibit breast cancer in obese postmenopausal mouse models
Published in Nature communications (25-01-2021)“…Accumulating evidence indicates that obesity with its associated metabolic dysregulation, including hyperinsulinemia and aberrant circadian rhythms, increases…”
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Interaction of musleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing
Published in The EMBO journal (20-09-2006)“…In myotonic dystrophy (DM1), both inactivation of muscleblind proteins and increased levels of CUG‐BP1 are reported. These events have been shown to contribute…”
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13
Alternative RNA Splicing in Fatty Liver Disease
Published in Frontiers in endocrinology (Lausanne) (26-02-2021)“…Alternative RNA splicing is a process by which introns are removed and exons are assembled to construct different RNA transcript isoforms from a single…”
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14
Obesity, cancer risk, and time-restricted eating
Published in Cancer and metastasis reviews (01-09-2022)“…Obesity and the associated metabolic syndrome is considered a pandemic whose prevalence is steadily increasing in many countries worldwide. It is a complex,…”
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Alternative RNA Splicing in the Pathogenesis of Liver Disease
Published in Frontiers in endocrinology (Lausanne) (21-06-2017)“…Non-alcoholic fatty liver disease (NAFLD) is becoming increasingly prevalent due to the worldwide obesity epidemic and currently affects one-third of adults or…”
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Review article: autoimmune pancreatitis – management of an emerging disease
Published in Alimentary pharmacology & therapeutics (01-02-2011)“…Aliment Pharmacol Ther 2011; 33: 291–303 Summary Background Autoimmune pancreatitis is a steroid‐responsive inflammatory pancreatic disease considered to be…”
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Gonadotropin-Releasing Hormone Pulse Sensitivity of Follicle-Stimulating Hormone-β Gene Is Mediated by Differential Expression of Positive Regulatory Activator Protein 1 Factors and Corepressors SKIL and TGIF1
Published in Molecular endocrinology (Baltimore, Md.) (01-08-2011)“…Gonadotropin synthesis and release is dependent on pulsatile stimulation by the hypothalamic neuropeptide GnRH. Generally, slow GnRH pulses promote FSH…”
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Dry electrodes for electrocardiography
Published in Physiological measurement (01-09-2013)“…Patient biopotentials are usually measured with conventional disposable Ag/AgCl electrodes. These electrodes provide excellent signal quality but are…”
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Small molecule activators of the Trk receptors for neuroprotection
Published in BMC neuroscience (03-12-2008)“…The neurotrophin signaling network is critical to the development and survival of many neuronal populations. Especially sensitive to imbalances in the…”
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Hepatocyte Deletion of IGF2 Prevents DNA Damage and Tumor Formation in Hepatocellular Carcinoma
Published in Advanced science (01-07-2022)“…Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Serine‐arginine rich splicing factor 3 (SRSF3) plays a critical role in hepatocyte…”
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