Search Results - "Weber, Scott"
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Signature pathway expression of xylose utilization in the genetically engineered industrial yeast Saccharomyces cerevisiae
Published in PloS one (05-04-2018)“…Haploid laboratory strains of Saccharomyces cerevisiae are commonly used for genetic engineering to enable their xylose utilization but little is known about…”
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2
Genomics Education in the Era of Personal Genomics: Academic, Professional, and Public Considerations
Published in International journal of molecular sciences (24-01-2020)“…Since the completion of the Human Genome Project in 2003, genomic sequencing has become a prominent tool used by diverse disciplines in modern science. In the…”
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3
Effect of Shift, Schedule, and Volume on Interpretive Accuracy: A Retrospective Analysis of 2.9 Million Radiologic Examinations
Published in Radiology (01-04-2018)“…Purpose To determine whether there is an association between radiologist shift length, schedule, or examination volume and interpretive accuracy. Materials and…”
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Exposome and Immunity Training: How Pathogen Exposure Order Influences Innate Immune Cell Lineage Commitment and Function
Published in International journal of molecular sciences (11-11-2020)“…Immune memory is a defining characteristic of adaptive immunity, but recent work has shown that the activation of innate immunity can also improve…”
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Two New Native β-Glucosidases from Clavispora NRRL Y-50464 Confer Its Dual Function as Cellobiose Fermenting Ethanologenic Yeast
Published in PloS one (24-03-2016)“…Yeast strain Clavispora NRRL Y-50464 is able to produce cellulosic ethanol from lignocellulosic materials without addition of external β-glucosidase by…”
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Tolerant industrial yeast Saccharomyces cerevisiae posses a more robust cell wall integrity signaling pathway against 2-furaldehyde and 5-(hydroxymethyl)-2-furaldehyde
Published in Journal of biotechnology (20-06-2018)“…•All five sensor genes of both strains were activated for the cell wall integrity pathway against furfural-HMF.•The industrial yeast Y-50049 demonstrated a…”
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Selection of human single domain antibodies (sdAb) against thymidine kinase 1 and their incorporation into sdAb-Fc antibody constructs for potential use in cancer therapy
Published in PloS one (03-03-2022)“…Thymidine Kinase 1 (TK1) is primarily known as a cancer biomarker with good prognostic capabilities for both hematological and solid malignancies. However,…”
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Phaeohyphomycosis due to Veronaea botryosa in cultured white sturgeon (Acipenser transmontanus Richardson) from California USA during 2006 to 2015
Published in Journal of fish diseases (01-06-2021)“…Infection with Veronaea botryosa can result in rare cutaneous or disseminated, granulomatous to pyogranulomatous phaeohyphomycosis in humans, although disease…”
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Interleukin-10 enhances activity of ventral tegmental area dopamine neurons resulting in increased dopamine release
Published in Brain, behavior, and immunity (01-10-2023)“…•Interleukin-10 (IL-10) increases ventral tegmental area (VTA) dopamine firing.•IL-10 receptor expression is present in dopamine and non-dopamine cells of the…”
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10
Characterizing the Interplay of Lymphocytes in Graves' Disease
Published in International journal of molecular sciences (01-04-2023)“…Graves' disease (GD) is a thyroid-specific autoimmune disease with a high prevalence worldwide. The disease is primarily mediated by B cells, which produce…”
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Application of novel CAR technologies to improve treatment of autoimmune disease
Published in Frontiers in immunology (09-10-2024)“…Chimeric antigen receptor (CAR) T cell therapy has become an important treatment for hematological cancers, and its success has spurred research into CAR T…”
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12
The Role of Atypical Chemokine Receptors in Neuroinflammation and Neurodegenerative Disorders
Published in International journal of molecular sciences (01-11-2023)“…Neuroinflammation is associated with several neurodegenerative disorders, including Alzheimer’s disease (AD), Parkinson’s disease (PD), and multiple sclerosis…”
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Personal microbiome analysis improves student engagement and interest in Immunology, Molecular Biology, and Genomics undergraduate courses
Published in PloS one (11-04-2018)“…A critical area of emphasis for science educators is the identification of effective means of teaching and engaging undergraduate students. Personal microbiome…”
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14
Meta-Analysis of Two Human RNA-seq Datasets to Determine Periodontitis Diagnostic Biomarkers and Drug Target Candidates
Published in International journal of molecular sciences (17-05-2022)“…Periodontitis is a chronic inflammatory oral disease that affects approximately 42% of adults 30 years of age or older in the United States. In response to…”
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Alternative CAR Therapies: Recent Approaches in Engineering Chimeric Antigen Receptor Immune Cells to Combat Cancer
Published in Biomedicines (24-06-2022)“…For nearly three decades, chimeric antigen receptors (CARs) have captivated the interest of researchers seeking to find novel immunotherapies to treat cancer…”
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Removal of Antibiotics in Wastewater: Effect of Hydraulic and Solid Retention Times on the Fate of Tetracycline in the Activated Sludge Process
Published in Environmental science & technology (01-08-2005)“…A study was conducted to examine the influence of hydraulic retention time (HRT) and solid retention time (SRT) on the removal of tetracycline in the activated…”
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Trpm4 differentially regulates Th1 and Th2 function by altering calcium signaling and NFAT localization
Published in The Journal of immunology (1950) (01-09-2010)“…Th cell subsets have unique calcium (Ca(2+)) signals when activated with identical stimuli. The regulation of these Ca(2+) signals and their correlation to the…”
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Atypical chemokine receptor ACKR2-V41A has decreased CCL2 binding, scavenging, and activation, supporting sustained inflammation and increased Alzheimer’s disease risk
Published in Scientific reports (15-05-2020)“…A recent genome-wide association study (GWAS) of 59 cerebrospinal fluid (CSF) proteins with a connection to Alzheimer’s disease (AD) demonstrated an…”
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T Cell Calcium Signaling Regulation by the Co-Receptor CD5
Published in International journal of molecular sciences (26-04-2018)“…Calcium influx is critical for T cell effector function and fate. T cells are activated when T cell receptors (TCRs) engage peptides presented by…”
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Immunomodulatory role of oral microbiota in inflammatory diseases and allergic conditions
Published in Frontiers in allergy (17-02-2023)“…In recent years, the interplay between oral microbiota and systemic disease has gained attention as poor oral health is associated with several pathologies…”
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