Search Results - "Weber, Sarah R."
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Role of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelium Dysfunction
Published in Frontiers in cell and developmental biology (25-06-2020)“…Retinal pigment epithelial (RPE) cells maintain the health and functional integrity of both photoreceptors and the choroidal vasculature. Loss of RPE…”
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Neurodegeneration, Neuroprotection and Regeneration in the Zebrafish Retina
Published in Cells (Basel, Switzerland) (12-03-2021)“…Neurodegenerative retinal diseases, such as glaucoma and diabetic retinopathy, involve a gradual loss of neurons in the retina as the disease progresses…”
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Extracellular vesicles from retinal pigment epithelial cells expressing R345W‐Fibulin‐3 induce epithelial‐mesenchymal transition in recipient cells
Published in Journal of extracellular vesicles (01-10-2023)“…Abstract We have shown previously that expression of R345W‐Fibulin‐3 induces epithelial‐mesenchymal transition (EMT) in retinal pigment epithelial (RPE) cells…”
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Expression of R345W-Fibulin-3 Induces Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells
Published in Frontiers in cell and developmental biology (19-06-2020)“…To investigate the role of protein misfolding in retinal pigment epithelial (RPE) cell dysfunction, the effects of R345W-Fibulin-3 expression on RPE cell…”
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Proteomic Analysis of Early Diabetic Retinopathy Reveals Mediators of Neurodegenerative Brain Diseases
Published in Investigative ophthalmology & visual science (01-05-2018)“…Current evidence suggests that retinal neurodegeneration is an early event in the pathogenesis of diabetic retinopathy. Our main goal was to examine whether,…”
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Descriptive analysis of Fibulin-3 and the extracellular vesicle marker, Alix, in drusen from a small cohort of postmortem human eyes
Published in Experimental eye research (01-02-2021)“…Fibulin-3 (Fib3) is a secreted glycoprotein that is expressed in the retina and has been associated with drusen formation in age-related macular degeneration…”
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Susceptibility-weighted imaging of retinal hemorrhages in abusive head trauma
Published in Pediatric radiology (01-02-2019)“…Background Retinal hemorrhages are one of the most important supportive evidences for abusive head trauma (AHT). Susceptibility-weighted imaging (SWI) is…”
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Identification of Early Biochemical Changes in the Diabetic Retina Using an Unbiased Proteomics Approach
Published in Diabetes (New York, N.Y.) (01-07-2018)“…Diabetic retinopathy (DR) remains a leading cause of blindness in developed countries. Current treatments target late stages of DR when vision has already been…”
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Liquid Biopsy of Vitreous Reveals an Abundant Vesicle Population Consistent With the Size and Morphology of Exosomes
Published in Translational vision science & technology (01-05-2018)“…To investigate the molecular components of the vitreous in order to better understand retinal physiology and disease. Vitreous was acquired from patients…”
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A validated analysis pipeline for mass spectrometry-based vitreous proteomics: new insights into proliferative diabetic retinopathy
Published in Clinical proteomics (03-12-2021)“…Vitreous is an accessible, information-rich biofluid that has recently been studied as a source of retinal disease-related proteins and pathways. However, the…”
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Proteomic Analyses of Vitreous in Proliferative Diabetic Retinopathy: Prior Studies and Future Outlook
Published in Journal of clinical medicine (25-05-2021)“…Vitreous fluid is becoming an increasingly popular medium for the study of retinal disease. Numerous studies have demonstrated that proteomic analysis of the…”
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Correlation of endoscopic disease severity with pediatric ulcerative colitis activity index score in children and young adults with ulcerative colitis
Published in World journal of gastroenterology : WJG (14-05-2017)“…AIM To investigate of pediatric ulcerative colitis activity index(PUCAI) in ulcerative colitis correlate with mucosal inflammation and endoscopic assessment of…”
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