Search Results - "Weber, Michael H.W"

Bacterial cold shock responses by WEBER, MICHAEL H. W., MARAHIEL, MOHAMED A.

“…As a measure for molecular motion, temperature is one of the most important environmental factors for life as it directly influences structural and hence…”
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Specific polar localization of ribosomes in Bacillus subtilis depends on active transcription by Mascarenhas, Judita, Weber, Michael H W, Graumann, Peter L

“…The large subunit of ribosomes in Bacillus subtilis was tagged by generation of a fusion of ribosomal protein L1 to blue fluorescent protein (BFP). The fusion…”
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Northern blot detection of endogenous small RNAs (~14 nt) in bacterial total RNA extracts by Beckmann, Benedikt M, Grünweller, Arnold, Weber, Michael H.W, Hartmann, Roland K

“…Here we describe a northern blot procedure that allows the detection of endogenous RNAs as small as ~14 nt in total RNA extracts from bacteria. RNAs that small…”
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Impact of rRNA methylations on ribosome recycling and fidelity of initiation in Escherichia coli by Seshadri, Anuradha, Dubey, Badrinath, Weber, Michael H.W, Varshney, Umesh

“…Ribosomal RNA (rRNA) contains a number of modified nucleosides in functionally important regions including the intersubunit bridge regions. As the activity of…”
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Investigation of catalysis by bacterial RNase P via LNA and other modifications at the scissile phosphodiester by Cuzic-Feltens, Simona, Weber, Michael H.W, Hartmann, Roland K

“…We analyzed cleavage of precursor tRNAs with an LNA, 2'-OCH₃, 2'-H or 2'-F modification at the canonical (c₀) site by bacterial RNase P. We infer that the…”
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A family of cold shock proteins in Bacillus subtilis is essential for cellular growth and for efficient protein synthesis at optimal and low temperatures by Graumann, Peter, Wendrich, Thomas M., Weber, Michael H.W., Schröder, Katja, Marahiel, Mohamed A.

“…Like other bacteria, Bacillus subtilis possesses a family of homologous small acidic proteins (CspB, CspC and CspD, identity > 70%) that are strongly induced…”
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Drug Repurposing and De Novo Drug Discovery of Protein Kinase Inhibitors as New Drugs against Schistosomiasis by Pereira Moreira, Bernardo, Weber, Michael H W, Haeberlein, Simone, Mokosch, Annika S, Spengler, Bernhard, Grevelding, Christoph G, Falcone, Franco H

“…Schistosomiasis is a neglected tropical disease affecting more than 200 million people worldwide. Chemotherapy relies on one single drug, praziquantel, which…”
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Identification and characterisation of the tegument-expressed aldehyde dehydrogenase SmALDH_312 of Schistosoma mansoni, a target of disulfiram by Beutler, Mandy, Harnischfeger, Julie, Weber, Michael H.W., Hahnel, Steffen R., Quack, Thomas, Blohm, Ariane, Ueberall, Monique E., Timm, Thomas, Lochnit, Günter, Rennar, Georg A., Gallinger, Tom L., Houhou, Hicham, Rahlfs, Stefan, Falcone, Franco H., Becker, Katja, Schlitzer, Martin, Haeberlein, Simone, Czermak, Peter, Salzig, Denise, Grevelding, Christoph G.

“…Schistosomiasis is an infectious disease caused by blood flukes of the genus Schistosoma and affects approximately 200 million people worldwide. Since…”
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Are humanized IgE reporter systems potential game changers in serological diagnosis of human parasitic infection? by Prakash, Prema S., Weber, Michael H. W., van Hellemond, Jaap J., Falcone, Franco H.

“…Immunoglobulin E (IgE) is thought to have evolved to protect mammalian hosts against parasitic infections or toxins and plays a central role in the…”
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Phenotypic characterization and complementation analysis of Bacillus subtilis 6S RNA single and double deletion mutants by Hoch, Philipp G., Burenina, Olga Y., Weber, Michael H.W., Elkina, Daria A., Nesterchuk, Mikhail V., Sergiev, Petr V., Hartmann, Roland K., Kubareva, Elena A.

“…6S RNA, a global regulator of transcription in bacteria, binds to housekeeping RNA polymerase (RNAP) holoenzymes to competitively inhibit transcription from…”
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Biochemical Characterization of Pathogenic Mutations in Human Mitochondrial Methionyl-tRNA Formyltransferase by Sinha, Akesh, Köhrer, Caroline, Weber, Michael H.W., Masuda, Isao, Mootha, Vamsi K., Hou, Ya-Ming, RajBhandary, Uttam L.

“…N-Formylation of initiator methionyl-tRNA (Met-tRNAMet) by methionyl-tRNA formyltransferase (MTF) is important for translation initiation in bacteria,…”
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The Humanised NPY-mRFP RBL Reporter Cell Line Is a Fast and Inexpensive Tool for Detection of Allergen-Specific IgE in Human Sera by Prakash, Prema S, Barwary, Nafal J. S, Weber, Michael H. W, Wan, Daniel, Conejeros, Iván, Pereira Moreira, Bernardo, Alharbi, Waleed S, van Hellemond, Jaap J, Akinwale, Jude, Falcone, Franco H

“…Rat basophilic leukaemia (RBL) cells have been used for decades as a model of high-affinity Immunoglobulin E (IgE) receptor (FcεRI) signalling. Here, we…”
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Genomewide Transcriptional Analysis of the Cold Shock Response in Bacillus subtilis by Beckering, Carsten L., Steil, Leif, Weber, Michael H. W., Völker, Uwe, Marahiel, Mohamed A.

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Cold Shock Response of Bacillus subtilis: Isoleucine-Dependent Switch in the Fatty Acid Branching Pattern for Membrane Adaptation to Low Temperatures by Klein, W, Weber, M H, Marahiel, M A

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Coping with the cold: the cold shock response in the Gram-positive soil bacterium Bacillus subtilis by Weber, Michael H. W., Marahiel, Mohamed A.

“…All organisms examined to date, respond to a sudden change in environmental temperature with a specific cascade of adaptation reactions that, in some cases,…”
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Localization of Cold Shock Proteins to Cytosolic Spaces Surrounding Nucleoids in Bacillus subtilis Depends on Active Transcription by Weber, M H, Volkov, A V, Fricke, I, Marahiel, M A, Graumann, P L

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CSDBase: an interactive database for cold shock domain-containing proteins and the bacterial cold shock response by Weber, Michael H W, Fricke, Ingo, Doll, Niclas, Marahiel, Mohamed A

“…CSDBase (http://www.chemie.uni-marburg.de/~csdbase/) is an interactive Internet-embedded research platform providing detailed information on proteins…”
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