Search Results - "Weber, Martin"
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Can International Relations (IR) learn? The politics of 'doing understanding'
Published in Australian journal of international affairs (02-11-2023)“…This short response considers some challenges that may be faced by learners keen to engage with 'Indigenous International Relations' following the lecture by…”
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Toward identifying key mechanisms of progression in multiple sclerosis
Published in Trends in neurosciences (Regular ed.) (01-01-2024)“…A major therapeutic goal in the treatment of multiple sclerosis (MS) is to prevent the accumulation of disability over an often decades-long disease course…”
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Targeting B Cells and Microglia in Multiple Sclerosis With Bruton Tyrosine Kinase Inhibitors: A Review
Published in JAMA neurology (01-04-2023)“…Currently, disease-modifying therapies for multiple sclerosis (MS) use 4 mechanisms of action: immune modulation, suppressing immune cell proliferation,…”
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Bruton’s Tyrosine Kinase Inhibitors in Multiple Sclerosis: Pioneering the Path Towards Treatment of Progression?
Published in CNS drugs (01-10-2022)“…In multiple sclerosis (MS) persisting disability can derive from acute relapses or, alternatively, from slow and steady deterioration, termed chronic…”
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The urgent need to address health literacy in schools
Published in The Lancet (British edition) (04-02-2023)“…The Editorial1 raised an important question: why is health literacy failing so many? It urgently called for effective responses to support people to better…”
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Deciphering the Role of B Cells in Multiple Sclerosis-Towards Specific Targeting of Pathogenic Function
Published in International journal of molecular sciences (23-09-2017)“…B cells, plasma cells and antibodies may play a key role in the pathogenesis of multiple sclerosis (MS). This notion is supported by various immunological…”
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Emerging thin-film nanocomposite (TFN) membranes for reverse osmosis: A review
Published in Water research (Oxford) (15-04-2020)“…Thin-film composite (TFC) membranes are the heart of reverse osmosis (RO) processes for desalination and water reuse. In recent years, nanomaterials with high…”
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The Role of B Cells and Antibodies in Multiple Sclerosis, Neuromyelitis Optica, and Related Disorders
Published in Frontiers in immunology (08-02-2019)“…Our pathophysiological concept of the most common central nervous system demyelinating disease, multiple sclerosis, strikingly evolved by recent discoveries…”
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Placebo-Controlled Trial of an Oral BTK Inhibitor in Multiple Sclerosis
Published in The New England journal of medicine (20-06-2019)“…In a randomized trial, patients who received evobrutinib, an inhibitor of Bruton’s tyrosine kinase, at 75 mg daily had significantly fewer enhancing lesions on…”
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Credit Line Usage, Checking Account Activity, and Default Risk of Bank Borrowers
Published in The Review of financial studies (01-10-2010)“…Information on borrower quality is a fundamental issue in debt contracting, corporate and consumer finance, and financial intermediation. We investigate the…”
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CXCL13 is the major determinant for B cell recruitment to the CSF during neuroinflammation
Published in Journal of neuroinflammation (16-05-2012)“…The chemokines and cytokines CXCL13, CXCL12, CCL19, CCL21, BAFF and APRIL are believed to play a role in the recruitment of B cells to the central nervous…”
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Improving standards for primary care for children and adolescents in Europe, Central Asia and beyond: the WHO Pocket Book of Primary health care for children and adolescents
Published in Archives of disease in childhood (01-11-2022)“…Correspondence to Dr Susanne Carai, WHO Athens Quality of Care and Patient Safety Office, WHO Regional Office for Europe, Athens 10675, Greece; carais@who.int…”
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Defining distinct features of anti-MOG antibody associated central nervous system demyelination
Published in Therapeutic Advances in Neurological Disorders (01-01-2018)“…Extensive research over the last decades basically failed to identify a common cause of noninfectious inflammatory central nervous system (CNS) demyelinating…”
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Differential Effects of MS Therapeutics on B Cells-Implications for Their Use and Failure in AQP4-Positive NMOSD Patients
Published in International journal of molecular sciences (16-07-2020)“…B cells are considered major contributors to multiple sclerosis (MS) pathophysiology. While lately approved disease-modifying drugs like ocrelizumab deplete B…”
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Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis
Published in The Lancet (British edition) (01-05-2010)“…Summary Background The global burden of disease attributable to respiratory syncytial virus (RSV) remains unknown. We aimed to estimate the global incidence of…”
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B cells reappear less mature and more activated after their anti-CD20–mediated depletion in multiple sclerosis
Published in Proceedings of the National Academy of Sciences - PNAS (13-10-2020)“…B cell depletion via anti-CD20 antibodies is a highly effective treatment for multiple sclerosis (MS). However, little is known about the maturation/activation…”
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Microglia: The Missing Link to Decipher and Therapeutically Control MS Progression?
Published in International journal of molecular sciences (27-03-2021)“…Therapeutically controlling chronic progression in multiple sclerosis (MS) remains a major challenge. MS progression is defined as a steady loss of parenchymal…”
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B Cell-Directed Therapeutics in Multiple Sclerosis: Rationale and Clinical Evidence
Published in CNS drugs (01-12-2016)“…Over the last decade, evidence condensed that B cells, B cell-derived plasma cells and antibodies play a key role in the pathogenesis and progression of…”
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Trogocytosis challenges the cellular specificity of lineage markers and monoclonal antibodies
Published in Nature reviews. Immunology (01-09-2023)“…The transfer of surface molecules between cells by trogocytosis challenges the concept of cell type-unique surface markers and indicates that monoclonal…”
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Effect of reduction in household air pollution on childhood pneumonia in Guatemala (RESPIRE): a randomised controlled trial
Published in The Lancet (British edition) (12-11-2011)“…Summary Background Pneumonia causes more child deaths than does any other disease. Observational studies have indicated that smoke from household solid fuel is…”
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