Search Results - "Weber, James"
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1
The macroeconomic effects of asset purchases revisited
Published in Journal of macroeconomics (01-12-2018)“…This paper revisits the macroeconomic effects of the large-scale asset purchase programmes launched by the Federal Reserve and the Bank of England from 2008…”
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Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells
Published in Cancer research (Chicago, Ill.) (01-07-2016)“…Metformin (Met) is an approved antidiabetic drug currently being explored for repurposing in cancer treatment based on recent evidence of its apparent…”
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Clinical sequencing of the retinitis pigmentosa gene RPGR in over 1,000 cases of vision loss
Published in Molecular vision (19-02-2024)“…pathogenic variants are the major cause of X-linked retinitis pigmentosa. Here, we report the results from 1,033 clinical DNA tests that included sequencing of…”
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Genetic Structure and History of Africans and African Americans
Published in Science (American Association for the Advancement of Science) (22-05-2009)“…Africa is the source of all modern humans, but characterization of genetic variation and of relationships among populations across the continent has been…”
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The genetic structure of Pacific Islanders
Published in PLoS genetics (01-01-2008)“…Human genetic diversity in the Pacific has not been adequately sampled, particularly in Melanesia. As a result, population relationships there have been open…”
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Minimal Climate Impacts From Short‐Lived Climate Forcers Following Emission Reductions Related to the COVID‐19 Pandemic
Published in Geophysical research letters (28-10-2020)“…We present an assessment of the impacts on atmospheric composition and radiative forcing of short‐lived pollutants following a worldwide decrease in…”
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Variant curation expert panel recommendations for RYR1 pathogenicity classifications in malignant hyperthermia susceptibility
Published in Genetics in medicine (01-07-2021)“…As a ClinGen Expert Panel (EP) we set out to adapt the American College of Medical Genetics and Genomics (ACMG)/Association for Molecular Pathology (AMP)…”
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Chemistry-driven changes strongly influence climate forcing from vegetation emissions
Published in Nature communications (23-11-2022)“…Biogenic volatile organic compounds (BVOCs) affect climate via changes to aerosols, aerosol-cloud interactions (ACI), ozone and methane. BVOCs exhibit…”
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Climate-driven Chemistry and Aerosol Feedbacks in CMIP6 Earth System Models
Published in Atmospheric chemistry and physics (27-01-2021)“…Feedbacks play a fundamental role in determining the magnitude of the response of the climate system to external forcing, such as from anthropogenic emissions…”
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Genetic Structure of Human Populations
Published in Science (American Association for the Advancement of Science) (20-12-2002)“…We studied human population structure using genotypes at 377 autosomal microsatellite loci in 1056 individuals from 52 populations. Within-population…”
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Angiogenesis is Differentially Modulated by Anthocyanin and Phenolic Acid Extracts from Wild Blueberry ( V. angustifolium ) Through PI3K Pathway
Published in Journal of medicinal food (01-03-2021)“…Wild blueberries rank very high in anthocyanins (ACNs) and phenolic acids (PA) among other berries. Previous work from our group has documented their…”
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Atmospheric isoprene measurements reveal larger-than-expected Southern Ocean emissions
Published in Nature communications (22-03-2024)“…Isoprene is a key trace component of the atmosphere emitted by vegetation and other organisms. It is highly reactive and can impact atmospheric composition and…”
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Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations
Published in The Journal of biological chemistry (30-01-2015)“…Familial cerebral cavernous malformations (CCMs) are predominantly neurovascular lesions and are associated with mutations within the KRIT1, CCM2, and PDCD10…”
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Combined immune checkpoint protein blockade and low dose whole body irradiation as immunotherapy for myeloma
Published in Journal for immunotherapy of cancer (20-01-2015)“…Multiple myeloma is characterized by the presence of transformed neoplastic plasma cells in the bone marrow and is generally considered to be an incurable…”
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Human Diallelic Insertion/Deletion Polymorphisms
Published in American journal of human genetics (01-10-2002)“…We report the identification and characterization of 2,000 human diallelic insertion/deletion polymorphisms (indels) distributed throughout the human genome…”
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Global agricultural N2O emission reduction strategies deliver climate benefits with minimal impact on stratospheric O3 recovery
Published in NPJ climate and atmospheric science (07-06-2024)“…Agricultural nitrous oxide (N 2 O) emission reduction strategies are required given the potency of N 2 O as a greenhouse gas. However, the growing influence of…”
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Discovering the Millennials' Personal Values Orientation: A Comparison to Two Managerial Populations
Published in Journal of business ethics (01-07-2017)“…Values theory posits that individuals have values and they are formed by upbringing and life's experiences and influence an individuals' cognitive processes,…”
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Low levels of genetic divergence across geographically and linguistically diverse populations from India
Published in PLoS genetics (01-12-2006)“…Ongoing modernization in India has elevated the prevalence of many complex genetic diseases associated with a western lifestyle and diet to near-epidemic…”
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Homozygous WNT3 Mutation Causes Tetra-Amelia in a Large Consanguineous Family
Published in American journal of human genetics (01-03-2004)“…Tetra-amelia is a rare human genetic disorder characterized by complete absence of all four limbs and other anomalies. We studied a consanguineous family with…”
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