Search Results - "Weber, Jacob J."

Iron binding and release properties of transferrin-1 from Drosophila melanogaster and Manduca sexta: Implications for insect iron homeostasis by Weber, Jacob J., Kanost, Michael R., Gorman, Maureen J.

“…Transferrins belong to an ancient family of extracellular proteins. The best-characterized transferrins are mammalian proteins that function in iron…”
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A conserved asparagine residue stabilizes iron binding in Manduca sexta transferrin-1 by Weber, Jacob J., Geisbrecht, Brian V., Kanost, Michael R., Gorman, Maureen J.

“…Transferrin 1 (Tsf1) is an insect-specific iron-binding protein that is abundant in hemolymph and other extracellular fluids. It binds iron tightly at neutral…”
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Phenotypic analyses, protein localization, and bacteriostatic activity of Drosophila melanogaster transferrin-1 by Weber, Jacob J, Brummett, Lisa M, Coca, Michelle E, Tabunoki, Hiroko, Kanost, Michael R, Ragan, Emily J, Park, Yoonseong, Gorman, Maureen J

“…Transferrin-1 (Tsf1) is an extracellular insect protein with a high affinity for iron. The functions of Tsf1 are still poorly understood; however, Drosophila…”
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Structural insight into the novel iron‐coordination and domain interactions of transferrin‐1 from a model insect, Manduca sexta by Weber, Jacob J., Kashipathy, Maithri M., Battaile, Kevin P., Go, Eden, Desaire, Heather, Kanost, Michael R., Lovell, Scott, Gorman, Maureen J.

“…Transferrins function in iron sequestration and iron transport by binding iron tightly and reversibly. Vertebrate transferrins coordinate iron through…”
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Phylogenetic and sequence analyses of insect transferrins suggest that only transferrin 1 has a role in iron homeostasis by Najera, Diana G., Dittmer, Neal T., Weber, Jacob J., Kanost, Michael R., Gorman, Maureen J.

“…Iron is essential to life, but surprisingly little is known about how iron is managed in nonvertebrate animals. In mammals, the well‐characterized transferrins…”
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Secreted insect transferrin‐1 with strong and reversible iron‐binding has potentially tissue specific roles in immunity and iron transport by Weber, Jacob J., Park, Yoonseong J., Gorman, Maureen

“…Abstract only…”
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Characterization of Transferrin‐1 from Drosophila melanogaster by Gorman, Maureen J., Brummett, Lisa M., LeSuer, Leslie A., Weber, Jacob J., Kanost, MIchael R.

“…Transferrins are secreted proteins that bind iron. Mammalian serum transferrin is involved in iron transport, while mammalian lactoferrin functions as an…”
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