Search Results - "Weber, Georg"

Metabolism in cancer metastasis by Weber, Georg F.

“…Cancer metabolism has regained substantial research interest over recent years. The focus has been mostly on the primary tumor, while metabolic adjustments…”
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Cytokine storm and sepsis disease pathogenesis by Chousterman, Benjamin G., Swirski, Filip K., Weber, Georg F.

“…Infectious diseases are a leading cause of death worldwide. Sepsis is a severe clinical syndrome related to the host response to infection. The severity of…”
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Why does cancer therapy lack effective anti-metastasis drugs? by Weber, Georg F

“…Highlights ► The suppression of cancer metastasis is an urgent therapeutic need. ► Drugs that inhibit the dissemination of malignant cells will be broadly…”
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Effect of Hospital Volume on In-hospital Morbidity and Mortality Following Pancreatic Surgery in Germany by Krautz, Christian, Nimptsch, Ulrike, Weber, Georg F, Mansky, Thomas, Grützmann, Robert

“…OBJECTIVE:We aimed to determine the effect of hospital volume on in-hospital mortality, and failure to rescue following major pancreatic resections using…”
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Crossroads: the role of biomarkers in the management of lumps in the breast by Weber, Georg F

“…Premalignant lesions in the breast pose a difficult decision-making problem, whether to treat proactively and accept the side effects or to engage in watchful…”
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Nationwide In-hospital Mortality Following Pancreatic Surgery in Germany is Higher than Anticipated by Nimptsch, Ulrike, Krautz, Christian, Weber, Georg F, Mansky, Thomas, Grützmann, Robert

“…OBJECTIVE:We aimed to determine the unbiased mortality rates for pancreatic surgery procedures at the national level through a comprehensive analysis of every…”
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Meta-analysis of Osteopontin splice variants in cancer by An, Yu, Fnu, Gulimirerouzi, Xie, Changchun, Weber, Georg F

“…The cytokine Osteopontin is a mediator of tumor progression and cancer metastasis. In 2006, we reported that (in addition to the full-length form -a) splice…”
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Osteopontin induces mitochondrial biogenesis in deadherent cancer cells by Fnu, Gulimirerouzi, Weber, Georg F.

“…Metastasizing cells display a unique metabolism, which is very different from the Warburg effect that arises in primary tumors. Over short time frames,…”
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Time and Circumstances: Cancer Cell Metabolism at Various Stages of Disease Progression by Weber, Georg F

“…Over the past decade, research into the unique ways, in which cancer cells skew their metabolism, has had a renaissance-for the repeated time over more than 80…”
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The Effect of GPRC5a on the Proliferation, Migration Ability, Chemotherapy Resistance, and Phosphorylation of GSK-3β in Pancreatic Cancer by Liu, Bin, Yang, Hai, Pilarsky, Christian, Weber, Georg F

“…Pancreatic cancer (PaCa) is the fourth leading cause of cancer-related death, and personalized targeted cancer therapy is becoming a promising treatment…”
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The Phylogeny of Osteopontin-Analysis of the Protein Sequence by Weber, Georg F

“…Osteopontin (OPN) is important for tissue remodeling, cellular immune responses, and calcium homeostasis in milk and urine. In pathophysiology, the biomolecule…”
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The Multi-GNSS Experiment (MGEX) of the International GNSS Service (IGS) – Achievements, prospects and challenges by Montenbruck, Oliver, Steigenberger, Peter, Prange, Lars, Deng, Zhiguo, Zhao, Qile, Perosanz, Felix, Romero, Ignacio, Noll, Carey, Stürze, Andrea, Weber, Georg, Schmid, Ralf, MacLeod, Ken, Schaer, Stefan

“…Over the past five years, the International GNSS Service (IGS) has made continuous efforts to extend its service from GPS and GLONASS to the variety of newly…”
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Current Clinical Strategies of Pancreatic Cancer Treatment and Open Molecular Questions by Brunner, Maximilian, Wu, Zhiyuan, Krautz, Christian, Pilarsky, Christian, Grützmann, Robert, Weber, Georg F

“…Pancreatic cancer is one of the most lethal malignancies and is associated with a poor prognosis. Surgery is considered the only potential curative treatment…”
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Comparison of Cinematic Rendering and Computed Tomography for Speed and Comprehension of Surgical Anatomy by Elshafei, Moustafa, Binder, Johannes, Baecker, Justus, Brunner, Maximilian, Uder, Michael, Weber, Georg F, Grützmann, Robert, Krautz, Christian

“…Three-dimensional (3-D) volume rendering has been shown to improve visualization in general surgery. Cinematic rendering (CR), a novel 3-D visualization…”
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Local proliferation dominates lesional macrophage accumulation in atherosclerosis by Robbins, Clinton S, Hilgendorf, Ingo, Weber, Georg F, Theurl, Igor, Iwamoto, Yoshiko, Figueiredo, Jose-Luiz, Gorbatov, Rostic, Sukhova, Galina K, Gerhardt, Louisa M S, Smyth, David, Zavitz, Caleb C J, Shikatani, Eric A, Parsons, Michael, van Rooijen, Nico, Lin, Herbert Y, Husain, Mansoor, Libby, Peter, Nahrendorf, Matthias, Weissleder, Ralph, Swirski, Filip K

“…Macrophages are abundant in atherosclerotic plaques and are a pivotal cell type in plaque formation and progression. But how do they get there? Filip Swirski…”
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Alterations of Ion Homeostasis in Cancer Metastasis: Implications for Treatment by Fnu, Gulimirerouzi, Weber, Georg F

“…We have previously reported that metastases from all malignancies are characterized by a core program of gene expression that suppresses extracellular matrix…”
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Integrated Biosensor for Rapid and Point-of-Care Sepsis Diagnosis by Min, Jouha, Nothing, Maria, Coble, Ben, Zheng, Hui, Park, Jongmin, Im, Hyungsoon, Weber, Georg F, Castro, Cesar M, Swirski, Filip K, Weissleder, Ralph, Lee, Hakho

“…Sepsis is an often fatal condition that arises when the immune response to an infection causes widespread systemic organ injury. A critical unmet need in…”
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Molecular mechanisms of metastasis by Weber, Georg F

“…Abstract Metastasis formation is an essential aspect of cancer, for which the molecular underpinning has long been subject to debate. Although the organ…”
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Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis by Weber, Georg F., Chousterman, Benjamin G., He, Shun, Fenn, Ashley M., Nairz, Manfred, Anzai, Atsushi, Brenner, Thorsten, Uhle, Florian, Iwamoto, Yoshiko, Robbins, Clinton S., Noiret, Lorette, Maier, Sarah L., Zönnchen, Tina, Rahbari, Nuh N., Schölch, Sebastian, Klotzsche-von Ameln, Anne, Chavakis, Triantafyllos, Weitz, Jürgen, Hofer, Stefan, Weigand, Markus A., Nahrendorf, Matthias, Weissleder, Ralph, Swirski, Filip K.

“…Sepsis is a frequently fatal condition characterized by an uncontrolled and harmful host reaction to microbial infection. Despite the prevalence and severity…”
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Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis by Deniset, Justin F., Belke, Darrell, Lee, Woo-Yong, Jorch, Selina K., Deppermann, Carsten, Hassanabad, Ali Fatehi, Turnbull, Jeannine D., Teng, Guoqi, Rozich, Isaiah, Hudspeth, Kelly, Kanno, Yuka, Brooks, Stephen R., Hadjantonakis, Anna-Katerina, O’Shea, John J., Weber, Georg F., Fedak, Paul W.M., Kubes, Paul

“…Macrophages play an important role in structural cardiac remodeling and the transition to heart failure following myocardial infarction (MI). Previous research…”
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