Search Results - "Weber, Armin A."

Orbitrap technology for comprehensive metabolite-based liquid chromatographic–high resolution-tandem mass spectrometric urine drug screening – Exemplified for cardiovascular drugs by Helfer, Andreas G., Michely, Julian A., Weber, Armin A., Meyer, Markus R., Maurer, Hans H.

“…LC–high resolution (HR)-MS well established in proteomics has become more and more important in bioanalysis of small molecules over the last few years. Its…”
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Analysis of α- and β-amanitin in Human Plasma at Subnanogram per Milliliter Levels by Reversed Phase Ultra-High Performance Liquid Chromatography Coupled to Orbitrap Mass Spectrometry by Bambauer, Thomas P, Wagmann, Lea, Weber, Armin A, Meyer, Markus R

“…Amatoxins are known to be one of the main causes of serious to fatal mushroom intoxication. Thorough treatment, analytical confirmation, or exclusion of…”
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Drugs of abuse screening in urine as part of a metabolite-based LC-MSn screening concept by Wissenbach, Dirk K., Meyer, Markus R., Remane, Daniela, Philipp, Anika A., Weber, Armin A., Maurer, Hans H.

“…Today, immunoassays and several chromatographic methods are in use for drug screening in clinical and forensic toxicology and in doping control. For further…”
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Use of liquid chromatography coupled to low- and high-resolution linear ion trap mass spectrometry for studying the metabolism of paynantheine, an alkaloid of the herbal drug Kratom in rat and human urine by Philipp, Anika A, Wissenbach, Dirk K, Weber, Armin. A, Zapp, Josef, Zoerntlein, Siegfried W, Kanogsunthornrat, Jidapha, Maurer, Hans H

“…The Thai medicinal plant Mitragyna speciosa (Kratom in Thai) is misused as a herbal drug of abuse. During studies on the main Kratom alkaloid mitragynine (MG)…”
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Simultaneous analysis of antihyperglycemic small molecule drugs and peptide drugs by means of dual liquid chromatography high-resolution mass spectrometry by Vollmer, Aline C, Wagmann, Lea, Weber, Armin A, Meyer, Markus R

“…The study aimed to evaluate dual liquid chromatography (LC) coupled to high-resolution mass spectrometry (HRMS) for the simultaneous analysis of small and…”
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Liquid chromatography-high resolution-tandem mass spectrometry using Orbitrap technology for comprehensive screening to detect drugs and their metabolites in blood plasma by Helfer, Andreas G., Michely, Julian A., Weber, Armin A., Meyer, Markus R., Maurer, Hans H.

“…Orbitrap technology was successfully applied for broad metabolite-based LC-high resolution (HR)-MS screening of drugs in clinical and forensic toxicology. This…”
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Development and application of a strategy for analyzing eight biomarkers in human urine to verify toxic mushroom or ricinus communis ingestions by means of hydrophilic interaction LC coupled to HRMS/MS by Bambauer, Thomas P., Wagmann, Lea, Maurer, Hans H., Weber, Armin A., Meyer, Markus R.

“…The analytical proof of a toxic mushroom and/or plant ingestion at an early stage of a suspected intoxication can be crucial for fast therapeutic decision…”
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Development of the first metabolite-based LC-MS n urine drug screening procedure-exemplified for antidepressants by Wissenbach, Dirk K, Meyer, Markus R, Remane, Daniela, Weber, Armin A, Maurer, Hans H

“…In contrast to GC-MS libraries, currently available LC-MS libraries for toxicological detection contain besides parent drugs only some main metabolites…”
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Screening, library-assisted identification and validated quantification of oral antidiabetics of the sulfonylurea-type in plasma by atmospheric pressure chemical ionization liquid chromatography–mass spectrometry by Maurer, Hans H, Kratzsch, Carsten, Kraemer, Thomas, Peters, Frank T, Weber, Armin A

“…An atmospheric pressure chemical ionization liquid chromatographic–mass spectrometric (APCI–LC–MS) LC–MS assay is presented for fast and reliable screening and…”
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Development of the first metabolite-based LC-MS(n) urine drug screening procedure-exemplified for antidepressants by Wissenbach, Dirk K, Meyer, Markus R, Remane, Daniela, Weber, Armin A, Maurer, Hans H

“…In contrast to GC-MS libraries, currently available LC-MS libraries for toxicological detection contain besides parent drugs only some main metabolites…”
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Further development of a liquid chromatography–high‐resolution mass spectrometry/mass spectrometry‐based strategy for analyzing eight biomarkers in human urine indicating toxic mushroom or Ricinus communis ingestions by Bambauer, Thomas P., Wagmann, Lea, Weber, Armin A., Meyer, Markus R.

“…Recently, we presented a strategy for analysis of eight biomarkers in human urine to verify toxic mushroom or Ricinus communis ingestions. However, screening…”
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Nano liquid chromatography-high-resolution mass spectrometry for the identification of metabolites of the two new psychoactive substances N-(ortho-methoxybenzyl)-3,4-dimethoxyamphetamine and N-(ortho-methoxybenzyl)-4-methylmethamphetamine by Caspar, Achim T., Meyer, Markus R., Westphal, Folker, Weber, Armin A., Maurer, Hans H.

“…Among the emerging new psychoactive substances (NPS), compounds carrying an N-ortho-methoxybenzyl substituent, the so-called NBOMes, represented a highly…”
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Abuse of nutmeg seeds: Detectable by means of liquid chromatography‐mass spectrometry techniques? by Manier, Sascha K., Wagmann, Lea, Weber, Armin A., Meyer, Markus R.

“…Numerous case reports of intoxications with nutmeg seeds (Myristica fragrans, Houtt.) can be found in literature often following their abuse, as psychotropic…”
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Evaluation of novel organosilane modifications of paper spray mass spectrometry substrates for analyzing polar compounds by Bambauer, Thomas P., Maurer, Hans H., Weber, Armin A., Hannig, Matthias, Pütz, Norbert, Koch, Marcus, Manier, Sascha K., Schneider, Marc, Meyer, Markus R.

“…Paper spray mass spectrometry (PSMS) is currently used in different analytical fields, but less effort has been made so far to use PSMS for highly polar…”
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LC-HR-MS/MS standard urine screening approach: Pros and cons of automated on-line extraction by turbulent flow chromatography versus dilute-and-shoot and comparison with established urine precipitation by Helfer, Andreas G., Michely, Julian A., Weber, Armin A., Meyer, Markus R., Maurer, Hans H.

“…•Development, validation, and application of on-line extraction by turbulent flow chromatography for comprehensive drug screening with Orbitrap…”
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A validated GC-MS procedure for fast, simple, and cost-effective quantification of glycols and GHB in human plasma and their identification in urine and plasma developed for emergency toxicology by Meyer, Markus R., Weber, Armin A., Maurer, Hans H.

“…Methods developed for use in emergency toxicology have to be fast and simple. Additionally, such methods should be multi-analyte procedures because they allow…”
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Validated electrospray liquid chromatographic–mass spectrometric assay for the determination of the mushroom toxins α- and β-amanitin in urine after immunoaffinity extraction by Maurer, Hans H, Schmitt, Christian J, Weber, Armin A, Kraemer, Thomas

“…Specific detection of amanitins in body fluids is necessary for an early diagnosis of an intoxication with amanita mushrooms. In this paper, a liquid…”
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Phase I and II metabolites of speciogynine, a diastereomer of the main Kratom alkaloid mitragynine, identified in rat and human urine by liquid chromatography coupled to low‐ and high‐resolution linear ion trap mass spectrometry by Philipp, Anika A, Wissenbach, Dirk K, Weber, Armin A, Zapp, Josef, Maurer, Hans H

“…Mitragyna speciosa (Kratom in Thai), a Thai medical plant, is misused as herbal drug of abuse. Besides the most abundant alkaloids mitragynine (MG) and…”
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Towards a universal LC-MS screening procedure - can an LIT LC-MS(n) screening approach and reference library be used on a quadrupole-LIT hybrid instrument? by Wissenbach, Dirk K, Meyer, Markus R, Weber, Armin A, Remane, Daniela, Ewald, Andreas H, Peters, Frank T, Maurer, Hans H

“…In contrast to libraries with highly reproducible gas chromatography electron ionization mass spectra, current liquid chromatography (LC-MS) libraries are…”
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Metabolism studies of the Kratom alkaloids mitraciliatine and isopaynantheine, diastereomers of the main alkaloids mitragynine and paynantheine, in rat and human urine using liquid chromatography–linear ion trap-mass spectrometry by Philipp, Anika A., Wissenbach, Dirk K., Weber, Armin A., Zapp, Josef, Maurer, Hans H.

“…Mitragyna speciosa ( Kratom in Thai), native in Southeast Asia, is increasingly misused as a herbal drug of abuse. During metabolism studies on the Kratom…”
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