Search Results - "Weber, André A."
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Lactational delivery of Triclosan promotes non-alcoholic fatty liver disease in newborn mice
Published in Nature communications (27-07-2022)“…Here we show that Triclosan (TCS), a high-volume antimicrobial additive that has been detected in human breastmilk, can be efficiently transferred by lactation…”
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Effects of Early Life Oral Arsenic Exposure on Intestinal Tract Development and Lipid Homeostasis in Neonatal Mice: Implications for NAFLD Development
Published in Environmental health perspectives (01-09-2023)“…Newborns can be exposed to inorganic arsenic (iAs) through contaminated drinking water, formula, and other infant foods. Epidemiological studies have…”
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Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia
Published in Scientific reports (27-05-2021)“…Neonatal hyperbilirubinemia or jaundice is associated with kernicterus, resulting in permanent neurological damage or even death. Conventional phototherapy…”
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Regulation of Intestinal UDP-Glucuronosyltransferase 1A1 by the Farnesoid X Receptor Agonist Obeticholic Acid Is Controlled by Constitutive Androstane Receptor through Intestinal Maturation
Published in Drug metabolism and disposition (01-01-2021)“…UDP-glucuronosyltransferase (UGT) 1A1 is the only transferase capable of conjugating serum bilirubin. However, temporal delay in the development of the gene…”
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Triclosan administration to humanized UDP-glucuronosyltransferase 1 neonatal mice induces UGT1A1 through a dependence on PPARα and ATF4
Published in The Journal of biological chemistry (01-06-2024)“…Triclosan (TCS) is an antimicrobial toxicant found in a myriad of consumer products and has been detected in human tissues, including breastmilk. We have…”
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Oral arsenic administration to humanizedUDP-glucuronosyltransferase1 neonatal mice induces UGT1A1 through a dependence on Nrf2 and PXR
Published in The Journal of biological chemistry (01-03-2023)“…Inorganic arsenic (iAs) is an environmental toxicant that can lead to severe health consequences, which can be exacerbated if exposure occurs early in…”
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Effects of temperature manipulation on gamete development and reproductive activity in the farmed catfish Lophiosilurus alexandri
Published in Animal reproduction science (01-12-2022)“…Temperature is a critical factor for fish management, especially during breeding season. This study evaluated gametogenesis and gonadal maturation in the…”
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Intestinal UDP-Glucuronosyltransferase 1A1 and Protection against Irinotecan-Induced Toxicity in a Novel UDP-Glucuronosyltransferase 1A1 Tissue-Specific Humanized Mouse Model
Published in Drug metabolism and disposition (01-01-2022)“…The human UDP-glucuronosyltransferases (UGTs) represent an important family of drug-metabolizing enzymes, with UGT1A1 targeting the conjugation and…”
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Hirnvenen- und Sinusthrombose nach COVID-19-Schutzimpfung: Neurologisch-radiologisches Prozedere
Published in Radiologe (01-10-2021)“…Zusammenfassung Hintergrund Die vakzininduzierte zerebrale Venen- und Sinusthrombose (VI-CVST) nach Applikation der COVID-19-Vakzine ChAdOx1 nCov-19…”
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