Search Results - "Webb, Watt W"

Ionic strength-dependent persistence lengths of single-stranded RNA and DNA by Chen, Huimin, Meisburger, Steve P, Pabit, Suzette A, Sutton, Julie L, Webb, Watt W, Pollack, Lois

“…Dynamic RNA molecules carry out essential processes in the cell including translation and splicing. Base-pair interactions stabilize RNA into relatively rigid…”
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Compact and flexible raster scanning multiphoton endoscope capable of imaging unstained tissue by Rivera, David R, Brown, Christopher M, Ouzounov, Dimitre G, Pavlova, Ina, Kobat, Demirhan, Webb, Watt W, Xu, Chris

“…We present a compact and flexible endoscope (3-mm outer diameter, 4-cm rigid length) that utilizes a miniaturized resonant/nonresonant fiber raster scanner and…”
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Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles by Baumgart, Tobias, Hammond, Adam T, Sengupta, Prabuddha, Hess, Samuel T, Holowka, David A, Baird, Barbara A, Webb, Watt W

“…The membrane raft hypothesis postulates the existence of lipid bilayer membrane heterogeneities, or domains, supposed to be important for cellular function,…”
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Interpreting Second-Harmonic Generation Images of Collagen I Fibrils by Williams, Rebecca M., Zipfel, Warren R., Webb, Watt W.

“…Fibrillar collagen, being highly noncentrosymmetric, possesses a tremendous nonlinear susceptibility. As a result, second-harmonic generation (SHG) microscopy…”
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Identification of a helical intermediate in trifluoroethanol-induced alpha-synuclein aggregation by Anderson, Valerie L., Ramlall, Trudy F., Rospigliosi, Carla C., Webb, Watt W., Eliezer, David

“…Because oligomers and aggregates of the protein α-synuclein (αS) are implicated in the initiation and progression of Parkinson’s disease, investigation of…”
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Imaging coexisting fluid domains in biomembrane models coupling curvature and line tension by Webb, Watt W, Baumgart, Tobias, Hess, Samuel T

“…Lipid bilayer membranes-ubiquitous in biological systems and closely associated with cell function-exhibit rich shape-transition behaviour, including bud…”
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Mechanisms of Quenching of Alexa Fluorophores by Natural Amino Acids by Chen, Huimin, Ahsan, Syed S, Santiago-Berrios, Mitk’El B, Abruña, Hector D, Webb, Watt W

“…Quenching of fluorophores by the same proteins that they covalently label is a phenomenon that is neither well-known nor well-characterized. It is often…”
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Bright and Stable Core−Shell Fluorescent Silica Nanoparticles by Ow, Hooisweng, Larson, Daniel R, Srivastava, Mamta, Baird, Barbara A, Webb, Watt W, Wiesner, Ulrich

“…A class of highly fluorescent and photostable core−shell nanoparticles from a modified Stöber synthesis in the size range of 20−30 nm is described. These…”
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Precise Nanometer Localization Analysis for Individual Fluorescent Probes by Thompson, Russell E., Larson, Daniel R., Webb, Watt W.

“…Calculation of the centroid of the images of individual fluorescent particles and molecules allows localization and tracking in light microscopes to a…”
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Silica Nanoparticle Architecture Determines Radiative Properties of Encapsulated Fluorophores by Larson, Daniel R, Ow, Hooisweng, Vishwasrao, Harshad D, Heikal, Ahmed A, Wiesner, Ulrich, Webb, Watt W

“…Silica nanoparticles with embedded fluorescent molecules are used in a variety of applications requiring the observation of single nanoprobes. We describe a…”
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A Desolvation Model for Trifluoroethanol-Induced Aggregation of Enhanced Green Fluorescent Protein by Anderson, Valerie L., Webb, Watt W.

“…Studies of amyloid disease-associated proteins in aqueous solutions containing 2,2,2-trifluoroethanol (TFE) have shown that the formation of structural…”
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Neural Activity Triggers Neuronal Oxidative Metabolism Followed by Astrocytic Glycolysis by Kasischke, Karl A., Vishwasrao, Harshad D., Fisher, Patricia J., Zipfel, Warren R., Webb, Watt W.

“…We have found that two-photon fluorescence imaging of nicotinamide adenine dinucleotide (NADH) provides the sensitivity and spatial three-dimensional…”
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Live Tissue Intrinsic Emission Microscopy Using Multiphoton-Excited Native Fluorescence and Second Harmonic Generation by Zipfel, Warren R., Williams, Rebecca M., Christie, Richard, Nikitin, Alexander Yu, Hyman, Bradley T., Webb, Watt W.

“…Multicolor nonlinear microscopy of living tissue using two- and three-photon-excited intrinsic fluorescence combined with second harmonic generation by…”
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Water-Soluble Quantum Dots for Multiphoton Fluorescence Imaging in Vivo by Larson, Daniel R., Zipfel, Warren R., Williams, Rebecca M., Clark, Stephen W., Bruchez, Marcel P., Wise, Frank W., Webb, Watt W.

“…The use of semiconductor nanocrystals (quantum dots) as fluorescent labels for multiphoton microscopy enables multicolor imaging in demanding biological…”
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Focal Volume Optics and Experimental Artifacts in Confocal Fluorescence Correlation Spectroscopy by Hess, Samuel T., Webb, Watt W.

“…Fluorescence correlation spectroscopy (FCS) can provide a wealth of information about biological and chemical systems on a broad range of time scales (<1 μs to…”
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Polarized microtubule arrays in apical dendrites and axons by Kwan, Alex C, Dombeck, Daniel A, Webb, Watt W

“…The polarization of microtubules within neurons in vivo is crucial in their role of determining the directions and speeds of intracellular transport. More than…”
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Conformational Dependence of Intracellular NADH on Metabolic State Revealed by Associated Fluorescence Anisotropy by Vishwasrao, Harshad D., Heikal, Ahmed A., Kasischke, Karl A., Webb, Watt W.

“…Global analysis of fluorescence and associated anisotropy decays of intrinsic tissue fluorescence offers a sensitive and non-invasive probe of the…”
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Spt6 enhances the elongation rate of RNA polymerase II in vivo by Ardehali, M Behfar, Yao, Jie, Adelman, Karen, Fuda, Nicholas J, Petesch, Steven J, Webb, Watt W, Lis, John T

“…Several eukaryotic transcription factors have been shown to modulate the elongation rate of RNA polymerase II (Pol II) on naked or chromatin‐reconstituted…”
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In Vivo Multiphoton Microscopy of Deep Brain Tissue by Levene, Michael J, Dombeck, Daniel A, Kasischke, Karl A, Molloy, Raymond P, Webb, Watt W

“…School of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853 Submitted 20 October 2003; accepted in final form 1 December 2003…”
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In vivo imaging of unstained tissues using a compact and flexible multiphoton microendoscope by Brown, Christopher M, Rivera, David R, Pavlova, Ina, Ouzounov, Dimitre G, Williams, Wendy O, Mohanan, Sunish, Webb, Watt W, Xu, Chris

“…We use a compact and flexible multiphoton microendoscope (MPME) to acquire in vivo images of unstained liver, kidney, and colon from an anesthetized rat. The…”
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