Search Results - "Webb, Steve A.R"

Talking to the people that really matter about their participation in pandemic clinical research: A qualitative study in four European countries by Gobat, Nina H., Gal, Micaela, Butler, Christopher C., Webb, Steve A.R., Francis, Nicholas A., Stanton, Helen, Anthierens, Sibyl, Bastiaens, Hilde, Godycki‐ćwirko, Maciek, Kowalczyk, Anna, Pons‐Vigués, Mariona, Pujol‐Ribera, Enriqueta, Berenguera, Anna, Watkins, Angela, Sukumar, Prasanth, Moore, Ronald G., Hood, Kerenza, Nichol, Alistair

“…Background Pandemics of new and emerging infectious diseases are unpredictable, recurrent events that rapidly threaten global health and security. We aimed to…”
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Very old patients admitted to intensive care in Australia and New Zealand: a multi-centre cohort analysis by Bagshaw, Sean M, Webb, Steve A R, Delaney, Anthony, George, Carol, Pilcher, David, Hart, Graeme K, Bellomo, Rinaldo

“…Older age is associated with higher prevalence of chronic illness and functional impairment, contributing to an increased rate of hospitalization and admission…”
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Comment on Rishu et al. Time required to initiate outbreak and pandemic observational research by Gobat, Nina H, Butler, Christopher C, Webb, Steve A.R, Nichol, Alistair

“…Many of the delays to initiation of research arise from human behavior factors: reviewing protocols, agreeing data sharing arrangements and contract…”
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Long-term survival from intensive care : a review by WILLIAMS, Teresa A, DOBB, Geoffrey J, FINN, Judith C, WEBB, Steve A. R

“…To determine whether the long-term benefit of an ICU requires prolonged patient follow-up we reviewed long-term survival of patients from general ICUs. We…”
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The Efficacy of Earplugs as a Sleep Hygiene Strategy for Reducing Delirium in the ICU: A Systematic Review and Meta-Analysis by Litton, Edward, Carnegie, Vanessa, Elliott, Rosalind, Webb, Steve A R

“…OBJECTIVE:A systematic review and meta-analysis to assess the efficacy of earplugs as an ICU strategy for reducing delirium. DATA SOURCES:MEDLINE, EMBASE, and…”
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Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 by Gordon, Anthony C, Mouncey, Paul R, Al-Beidh, Farah, Rowan, Kathryn M, Nichol, Alistair D, Arabi, Yaseen M, Annane, Djillali, Beane, Abi, van Bentum-Puijk, Wilma, Berry, Lindsay R, Bhimani, Zahra, Bonten, Marc J M, Bradbury, Charlotte A, Brunkhorst, Frank M, Buzgau, Adrian, Cheng, Allen C, Detry, Michelle A, Duffy, Eamon J, Estcourt, Lise J, Fitzgerald, Mark, Goossens, Herman, Haniffa, Rashan, Higgins, Alisa M, Hills, Thomas E, Horvat, Christopher M, Lamontagne, Francois, Lawler, Patrick R, Leavis, Helen L, Linstrum, Kelsey M, Litton, Edward, Lorenzi, Elizabeth, Marshall, John C, Mayr, Florian B, McAuley, Daniel F, McGlothlin, Anna, McGuinness, Shay P, McVerry, Bryan J, Montgomery, Stephanie K, Morpeth, Susan C, Murthy, Srinivas, Orr, Katrina, Parke, Rachael L, Parker, Jane C, Patanwala, Asad E, Pettilä, Ville, Rademaker, Emma, Santos, Marlene S, Saunders, Christina T, Seymour, Christopher W, Shankar-Hari, Manu, Sligl, Wendy I, Turgeon, Alexis F, Turner, Anne M, van de Veerdonk, Frank L, Zarychanski, Ryan, Green, Cameron, Lewis, Roger J, Angus, Derek C, McArthur, Colin J, Berry, Scott, Webb, Steve A, Derde, Lennie P G

“…The interleukin-6 receptor blockers tocilizumab and sarilumab were tested against standard care in a randomized trial involving patients newly admitted to the…”
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Effect of Convalescent Plasma on Organ Support–Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial by Estcourt, Lise J, Turgeon, Alexis F, McQuilten, Zoe K, McVerry, Bryan J, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M, Arnold, Donald M, Beane, Abigail, Bégin, Philippe, van Bentum-Puijk, Wilma, Berry, Lindsay R, Bhimani, Zahra, Birchall, Janet E, Bonten, Marc J. M, Bradbury, Charlotte A, Brunkhorst, Frank M, Buxton, Meredith, Callum, Jeannie L, Chassé, Michaël, Cheng, Allen C, Cove, Matthew E, Daly, James, Derde, Lennie, Detry, Michelle A, De Jong, Menno, Evans, Amy, Fergusson, Dean A, Fish, Matthew, Fitzgerald, Mark, Foley, Claire, Goossens, Herman, Gordon, Anthony C, Gosbell, Iain B, Green, Cameron, Haniffa, Rashan, Harvala, Heli, Higgins, Alisa M, Hills, Thomas E, Hoad, Veronica C, Horvat, Christopher, Huang, David T, Hudson, Cara L, Ichihara, Nao, Laing, Emma, Lamikanra, Abigail A, Lamontagne, François, Lawler, Patrick R, Linstrum, Kelsey, Litton, Edward, Lorenzi, Elizabeth, MacLennan, Sheila, Marshall, John, McAuley, Daniel F, McDyer, John F, McGlothlin, Anna, McGuinness, Shay, Miflin, Gail, Montgomery, Stephanie, Mouncey, Paul R, Murthy, Srinivas, Nichol, Alistair, Parke, Rachael, Parker, Jane C, Priddee, Nicole, Purcell, Damian F. J, Reyes, Luis F, Richardson, Peter, Robitaille, Nancy, Rowan, Kathryn M, Rynne, Jennifer, Saito, Hiroki, Santos, Marlene, Saunders, Christina T, Serpa Neto, Ary, Seymour, Christopher W, Silversides, Jon A, Tinmouth, Alan A, Triulzi, Darrell J, Turner, Anne M, van de Veerdonk, Frank, Walsh, Timothy S, Wood, Erica M, Berry, Scott, Lewis, Roger J, Menon, David K, McArthur, Colin, Zarychanski, Ryan, Angus, Derek C, Webb, Steve A, Roberts, David J, Shankar-Hari, Manu

“…IMPORTANCE: The evidence for benefit of convalescent plasma for critically ill patients with COVID-19 is inconclusive. OBJECTIVE: To determine whether…”
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Randomised evaluation of active control of temperature versus ordinary temperature management (REACTOR) trial by Young, Paul J., Bailey, Michael J., Bass, Frances, Beasley, Richard W., Freebairn, Ross C., Hammond, Naomi E., van Haren, Frank M. P., Harward, Meg L., Henderson, Seton J., Mackle, Diane M., McArthur, Colin J., McGuinness, Shay P., Myburgh, John A., Saxena, Manoj K., Turner, Anne M., Webb, Steve A. R., Bellomo, Rinaldo

“…Purpose It is unknown whether protocols targeting systematic prevention and treatment of fever achieve lower mean body temperature than usual care in intensive…”
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Corticosteroid therapy for critically ill patients with COVID-19: A structured summary of a study protocol for a prospective meta-analysis of randomized trials by Sterne, Jonathan A C, Diaz, Janet, Villar, Jesús, Murthy, Srinivas, Slutsky, Arthur S, Perner, Anders, Jüni, Peter, Angus, Derek C, Annane, Djillali, Azevedo, Luciano Cesar Pontes, Du, Bin, Dequin, Pierre-Francois, Gordon, Anthony C, Green, Cameron, Higgins, Julian P T, Horby, Peter, Landray, Martin J, Lapadula, Giuseppe, Le Gouge, Amelie, Leclerc, Marie, Savović, Jelena, Tomazini, Bruno, Venkatesh, Balasubramanian, Webb, Steve, Marshall, John C

“…Primary objective: To estimate the effect of corticosteroids compared with usual care or placebo on mortality up to 28 days after randomization. Secondary…”
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Priority Needs for Conducting Pandemic-relevant Clinical Research With Children in Europe: A Consensus Study With Pediatric Clinician-researchers by Gal, Micaela, Gobat, Nina, Francis, Nicholas A, Hood, Kerenza, Butler, Christopher C, Bielicki, Julia, Fraaij, Pieter L, Sharland, Mike, Jarvis, Jessica, van Rossum, Annemarie M C, Heikkinen, Terho, Martinon-Torres, Federico, Herberg, Jethro, Watkins, Angela, Webb, Steve A R, Moore, Ronnie, Sukumar, Prasanth, Nichol, Alistair

“…BACKGROUND:Infectious disease (ID) pandemics pose a considerable global threat and can disproportionately affect vulnerable populations including children…”
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Key stakeholder perceptions about consent to participate in acute illness research: a rapid, systematic review to inform epi/pandemic research preparedness by Gobat, Nina H, Gal, Micaela, Francis, Nick A, Hood, Kerenza, Watkins, Angela, Turner, Jill, Moore, Ronald, Webb, Steve A R, Butler, Christopher C, Nichol, Alistair

“…A rigorous research response is required to inform clinical and public health decision-making during an epi/pandemic. However, the ethical conduct of such…”
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Preparing ICUs for pandemics by Gabriel, Lucinda E K, Webb, Steve A R

“…Influenza pandemics occur intermittently and represent an existential global infectious diseases threat. The purpose of this review is to describe clinical and…”
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The impact of bacterial and viral co‐infection in severe influenza by Blyth, Christopher C., Webb, Steve A. R., Kok, Jen, Dwyer, Dominic E., van Hal, Sebastiaan J., Foo, Hong, Ginn, Andrew N., Kesson, Alison M., Seppelt, Ian, Iredell, Jonathan R.

“…Please cite this paper as: Blyth et al. (2013) The impact of bacterial and viral co‐infection in severe influenza. Influenza and Other Respiratory Viruses 7(2)…”
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The ADRENAL study protocol: Adjunctive corticosteroid treatment in critically ill patients with septic shock by Venkatesh, Bala, Myburgh, John, Finfer, Simon, Webb, Steve A R, Cohen, Jeremy, Bellomo, Rinaldo, McArthur, Colin, Joyce, Christopher J, Rajbhandari, Dorrilyn, Glass, Parisa, Harward, Meg

“…Background: There is considerable global uncertainty on the role of low-dose corticosteroids in septic shock, which translates into variations in prescribing…”
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“Treatment goals: health care improvement through setting and measuring patient-centred outcomes” in the June 2013 issue of the Journal (Crit Care Resusc 2013; 15: 143–6) by Webb, Steve A.R., Litton, Ed, Leen, Timothy M.

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Oxygenation targets and monitoring in the critically ill: A point prevalence study of clinical practice in Australia and New Zealand by Young, Paul J, Beasley, Richard W, Capellier, Gilles, Eastwood, Glenn M, Webb, Steve A R

“…Background: Many critically ill patients require supplemental oxygen. However, the optimal oxygen saturation measured by pulse oximetry (SpO2) in intensive…”
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Urinary proteases degrade albumin: implications for measurement of albuminuria in stored samples by Kania, Kasia, Byrnes, Elizabeth A, Beilby, John P, Webb, Steve A R, Strong, Kimberley J

“…Previous studies have shown that albumin in stored urine samples degrades over time, and that albumin losses are greatest in samples with low pH conditions (pH…”
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Protocol and statistical analysis plan for the randomised evaluation of active control of temperature versus ordinary temperature management (REACTOR) trial by Young, Paul J, Bailey, Michael J, Beasley, Richard W, Freebairn, Ross C, Hammond, Naomi E, Haren, Frank M P van, Harward, Meg L, Henderson, Seton J, Mackle, Diane M, McArthur, Colin J, McGuinness, Shay P, Myburgh, John A, Saxena, Manoj K, Turner, Anne, Webb, Steve A R, Bellomo, Rinaldo

“…Background: Body temperature can be reduced in febrile patients in the intensive care unit using medicines and physical cooling devices, but it is not known…”
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Treatment goals: Health care improvement through setting and measuring patient-centred outcomes by Webb, Steve A R, Litton, Ed, Barned, Kerryn L, Crozier, Tim M

“…Health care costs are rising in a manner that is not sustainable, much health care spending is wasted, and quality of care is variable. Despite widespread and…”
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Bench-to-bedside review: the evaluation of complex interventions in critical care by Delaney, Anthony, Angus, Derek C, Bellomo, Rinaldo, Cameron, Peter, Cooper, D James, Finfer, Simon, Harrison, David A, Huang, David T, Myburgh, John A, Peake, Sandra L, Reade, Michael C, Webb, Steve A R, Yealy, Donald M

“…Complex interventions, such as the introduction of medical emergency teams or an early goal-directed therapy protocol, are developed from a number of…”
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