Search Results - "Webb, Sarah"
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Neutrophil to Lymphocyte Ratio (NLR) in captive chimpanzees (Pan troglodytes): The effects of sex, age, and rearing
Published in PloS one (16-12-2020)“…In humans, neutrophil to lymphocyte ratio (NLR) has been used as a clinical tool in diagnosis and/or prognosis of a variety of cancers and medical conditions,…”
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Taking it to the gut
Published in BioTechniques (01-03-2018)“…Sarah Webb examines how gastrointestinal organoids are transforming our understanding of biology and helping patients…”
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Going long and direct
Published in BioTechniques (01-02-2018)“…Sarah Webb explores how RNA sequencing innovations help scientists tackle the complexity of the transcriptome…”
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Are conspecific social videos rewarding to chimpanzees (Pan troglodytes)? A test of the social motivation theory
Published in PloS one (24-11-2021)“…Many claim that social stimuli are rewarding to primates, but few, if any, studies have explicitly demonstrated their reward value. Here, we examined whether…”
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DIGGING DESIGNER GENOMES
Published in BioTechniques (01-09-2015)“…Techniques such as Gibson and Golden Gate assembly and homologous recombination in yeast allow researchers to assemble DNA sequences millions of base pairs in…”
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THE DEPTHS OF CELL MIGRATION
Published in BioTechniques (01-07-2015)“…A growing number of researchers are trying to tease out the cellular mechanisms of tumor metastasis. Sarah Webb examines the tools they are using to probe the…”
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Captive chimpanzee (Pan troglodytes) behavior as a function of space per animal and enclosure type
Published in American journal of primatology (01-03-2018)“…Space per animal, or animal density, and enclosure type are important elements of functionally appropriate captive environments (FACEs) for chimpanzees. The…”
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Relationships between captive chimpanzee (Pan troglodytes) welfare and voluntary participation in behavioural studies
Published in Applied animal behaviour science (01-05-2019)“…•Higher behavioral diversity with participation in more behavioral studies over time.•No relationship between welfare and concurrent study participation…”
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Getting over qPCR's technical hurdles
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Matrix metalloproteinases (MMPs) mediate leukocyte recruitment during the inflammatory phase of zebrafish heart regeneration
Published in Scientific reports (08-05-2018)“…In zebrafish, the role of matrix metalloproteinases (MMPs) in the inflammatory phase of heart regeneration following cryoinjury remains poorly understood…”
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SUPPORTING MORE RELIABLE RESULTS
Published in BioTechniques (01-08-2015)“…Studies are finding that many groundbreaking published results with implications for human health and disease cannot be replicated. Sarah Webb explores how…”
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CELLS IN THE THIRD DIMENSION
Published in BioTechniques (01-03-2017)“…Sarah Webb explores the expanding tools and technologies for 3-D cell culture-from hydrogels to organs-on-a-chip…”
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Validation and utility of a body condition scoring system for chimpanzees (Pan troglodytes)
Published in American journal of primatology (01-10-2020)“…Obesity is a problem in captive chimpanzee colonies that can lead to increased risk for disease; therefore, implementation of effective weight management…”
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Differences in Behavior Between Elderly and Nonelderly Captive Chimpanzees and the Effects of the Social Environment
Published in Journal of the American Association for Laboratory Animal Science (01-11-2019)“…The population of NIH-owned or NIH-supported captive research chimpanzees is quickly becoming aged, and the 1998 NIH breeding moratorium has resulted in a…”
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Unraveling cancer through network models
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TPC2-mediated Ca2+ signaling is required for axon extension in caudal primary motor neurons in zebrafish embryos
Published in Journal of cell science (01-07-2020)“…The role of TPC2-mediated Ca2+ release was recently characterized in zebrafish during the establishment of the early spinal circuitry, one of the key events in…”
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Directing drug evolution
Published in BioTechniques (01-12-2017)“…Directed evolution is poised to change small molecule discovery and provide greater access to “drug space.” Sarah Webb looks into the evolving drug discovery…”
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PLANTS IN THE CRISPR
Published in BioTechniques (01-09-2017)“…Sarah Webb explores how researchers are using CRISPR/Cas9 to solve agricultural problems…”
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Localized TPC1-mediated Ca2+ release from endolysosomes contributes to myoseptal junction development in zebrafish
Published in Journal of cell science (01-05-2022)“…In the trunk of developing zebrafish embryos, adjacent myotome blocks transmit contractile force via myoseptal junctions (MJs), which are dynamic structures…”
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BOOTSTRAPPING BIOLOGY
Published in BioTechniques (01-10-2017)“…Sarah Webb explores how DIYbio strategies are helping biologists in traditional labs do better science…”
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