Search Results - "Webb, R.C."

Toll-like receptor 4 inhibition reduces vascular inflammation in spontaneously hypertensive rats by Bomfim, G.F., Echem, C., Martins, C.B., Costa, T.J., Sartoretto, S.M., Dos Santos, R.A., Oliveira, M.A., Akamine, E.H., Fortes, Z.B., Tostes, R.C., Webb, R.C., Carvalho, M.H.C.

“…Hypertension is associated with increased levels of circulating cytokines and recent studies have shown that innate immunity contributes to hypertension. The…”
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The adipokine chemerin augments vascular reactivity to contractile stimuli via activation of the MEK-ERK1/2 pathway by Lobato, N.S., Neves, K.B., Filgueira, F.P., Fortes, Z.B., Carvalho, M.H.C., Webb, R.C., Oliveira, A.M., Tostes, R.C.

“…Cytokines interfere with signaling pathways and mediators of vascular contraction. Endothelin-1 (ET-1) plays a major role on vascular dysfunction in conditions…”
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Mitochondrial-derived N -formyl peptides: Novel links between trauma, vascular collapse and sepsis by Wenceslau, C.F, McCarthy, C.G, Goulopoulou, S, Szasz, T, NeSmith, E.G, Webb, R.C

“…Abstract Sepsis is a major cause of mortality and morbidity in trauma patients despite aggressive treatment. Traumatic injury may trigger infective or…”
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Vascular O-GlcNAcylation augments reactivity to constrictor stimuli by prolonging phosphorylated levels of the myosin light chain by Lima, V V, Lobato, N S, Filgueira, F P, Webb, R C, Tostes, R C, Giachini, F R

“…O-GlcNAcylation is a modification that alters the function of numerous proteins. We hypothesized that augmented O-GlcNAcylation levels enhance myosin light…”
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STIM1/Orai1-mediated store-operated Ca2+ entry: the tip of the iceberg by Giachini, F R, Lima, V V, Hannan, J L, Carneiro, F S, Webb, R C, Tostes, R C

“…Highly efficient mechanisms regulate intracellular calcium (Ca2+) levels. The recent discovery of new components linking intracellular Ca2+ stores to plasma…”
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POD-05.11: The soluble guanylyl cyclase stimulator BAY 41-2272 reverses endothelial and nerve dysfunction in corpus cavernosum from spontaneously diabetic ( db/db -/-) mice by Teixeira, C.E, Priviero, F.B.M, Webb, R.C

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A key role for Na+/K+-ATPase in the endothelium-dependent oscillatory activity of mouse small mesenteric arteries by Giachini, F R C, Carneiro, F S, Lima, V V, Carneiro, Z N, Brands, M W, Webb, R C, Tostes, R C

“…Oscillatory contractile activity is an inherent property of blood vessels. Various cellular mechanisms have been proposed to contribute to oscillatory…”
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Leucine rich repeat containing 8A anion channels modulate vascular reactivity in the pudendal artery by Choi, H., Nguyen, H., Priviero, F., Webb, R.C., Lamb, F.

“…Erectile dysfunction (ED) is characterized by an inability to develop or maintain penile erection during sexual activity. The internal pudendal artery (IPA) is…”
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022 Leucine Rich Repeat Containing 8A Anion Channels Modulate Vascular Reactivity in the Pudendal Artery by Choi, H., Nguyen, H., Priviero, F., Webb, R.C., Lamb, F.

“…ABSTRACT Introduction Erectile dysfunction (ED) is characterized by an inability to develop or maintain penile erection during sexual activity. The internal…”
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079 Deletion of Macrophage-Derived Toll-Like Receptor 9 Prevents Erectile Dysfunction in Mice Fed a High Fat Diet by Priviero, F., Calmasini, F., McCarthy, C.G., Wenceslau, C., Antunes, E., Webb, R.C.

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The magnetized steel and scintillator calorimeters of the MINOS experiment by Allison, W.W.M., Andreopoulos, C., Ayres, D.S., Barish, B., Barker, M.A., Barnes, P.D., Barrett, W.L., Beall, E., Becker, B.R., Bocean, V., Boehm, J., Border, P.M., Chernichenko, S.K., Choudhary, B.C., Courant, H., Dawson, J.W., de Jong, J.K., Drake, G., Ducar, R., Durkin, T., Escobar, C.O., Fackler, O.D., Falk Harris, E., Felt, N., Frohne, M.V., Gallagher, H.R., Godley, A., Goodman, M.C., Grossman, N., Grudzinski, J.J., Guarino, V., Habig, A., Hanson, J., Harris, D., Hartouni, E.P., Heller, K., Indurthy, D., Irwin, G.M., James, C., Jenner, L., Joffe-Minor, T., Kim, H., Koskinen, D.J., Kostin, M., Krakauer, D.A., Ladran, A.S., Laughton, C., Lee, R., Liu, J., Litchfield, P.J., Litchfield, R.P., Maher, E., McDonald, J., Merzon, G.I., Morse, R., Mualem, L., Murgia, S., Murtagh, M.J., Nelson, C., Nelson, J.K., Nichol, R.J., Onuchin, V.A., Paley, J., Paolone, V., Pavlović, Ž., Pearce, G.F., Pearson, N., Peterson, E.A., Price, L.E., Pushka, D.R., Rameika, R.A., Raufer, T.M., Reyna, D.E., Saakyan, R., Saoulidou, N., Schwienhorst, R., Semenov, V.K., Shanahan, P., Smirnitsky, V., Speakman, B., Swan, J.M., Tagg, N., Talaga, R.L., Terekhov, A., Tetteh-Lartey, E., Thomas, J., Trendler, R., Trevor, J., Vaziri, K., Wai, L., Ward, C.P., Webb, R.C., Wehmann, A., White, R.F., Wojcicki, S.G., Yan, W.G., Yang, T., Yun, J.C., Zheng, H., Zwaska, R.

“…The Main Injector Neutrino Oscillation Search (MINOS) experiment uses an accelerator-produced neutrino beam to perform precision measurements of the neutrino…”
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Design and production of the high voltage electrode grids and electron extraction region for the LZ dual-phase xenon time projection chamber by Linehan, R., Mannino, R.L., Fan, A., Ignarra, C.M., Luitz, S., Skarpaas, K., Shutt, T.A., Akerib, D.S., Alsum, S.K., Anderson, T.J., Araújo, H.M., Arthurs, M., Auyeung, H., Bailey, A.J., Biesiadzinski, T.P., Breidenbach, M., Cherwinka, J.J., Conley, R.A., Genovesi, J., Gilchriese, M.G.D., Glaenzer, A., Gonda, T.G., Hanzel, K., Hoff, M.D., Ji, W., Kaboth, A.C., Kravitz, S., Kurita, N.R., Lambert, A.R., Lesko, K.T., Lorenzon, W., Majewski, P.A., Miller, E.H., Monzani, M.E., Palladino, K.J., Ratcliff, B.N., Saba, J.S., Santone, D., Shutt, G.W., Stifter, K., Szydagis, M., Tomás, A., Va’vra, J., Waldron, W.L., Webb, R.C., White, R.G., Whitis, T.J., Wilson, K., Wisniewski, W.J.

“…The dual-phase xenon time projection chamber (TPC) is a powerful tool for direct-detection experiments searching for WIMP dark matter, other dark matter…”
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Near-intrinsic energy resolution for 30-662 keV gamma rays in a high pressure xenon electroluminescent TPC by Álvarez Puerta, Vicente, Cervera Villanueva, Anselmo, Borges, F. I.G, Cárcel García, Sara, Castel, J, Cebrián, S, Condel, C.A.N, Dafni, T, Dias, T.H.V.T, Díaz Medina, José, Egorov, M, Esteve, R, Evtoukhovitch, P, Fernandes, L.M. P, Ferrario, Paola, Ferreira, A.L, Freitas, E.D.C, Gehman, V.M, Gil, A, Goldschmidt, A, Gómez, H, Gómez Cadenas, Juan José, González-Díaz, D, Gutiérrez, R.M, Hauptman, J, Hernando Morata, J.A, Herrera, D.C, Iguaz, F.J, Irastorza, I.G, Jinete, M.A, Labarga, L, Liubarsky, Igor, Lopes, J.A.M, Lorca Galindo, David, Losada, M, Luzón, G, Marí, A, Martín-Albo Simón, Justo, Martínez Pérez, Alberto, Miller, T, Moiseenko, A, Monrabal Capilla, Francesc, Monteiro, C.M.B, Mora, F.J, Moutinho, L.M, Muñoz Vidal, J, Natal Da Luz, H, Navarro, G, Nebot Guinot, Miquel, Nygren, D, Oliveira, C.A.B, Palma, R, Pérez, J, Pérez Aparicio, J.L, Renner, J, Ripoll Masferrer, Lluís, Rodríguez, A, Rodríguez Samaniego, Javier, Santos, F. P, Dos Santos, J. M.F, Segui, L, Serra Díaz-Cano, Luis, Shuman, D, Simón Estévez, Ander, Sofka, C, Sorel, Michel, Toledo, J.F, Tomás, A, Torrent, J, Tsamalaidze, Z, Vázquez, D, Veloso, J.F.C.A, Villar, J.A, Webb, R.C, White, J.T, Yahlali Haddou, Nadia

“…We present the design, data and results from the NEXT prototype for Double Beta and Dark Matter (NEXT-DBDM) detector, a high-pressure gaseous natural xenon…”
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Calcium handling by vascular myocytes in hypertension by Tostes, R C, Wilde, D W, Bendhack, L M, Webb, R C

“…Calcium ions (Ca2+) trigger the contraction of vascular myocytes and the level of free intracellular Ca2+ within the myocyte is precisely regulated by…”
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LUX trigger efficiency by Akerib, D.S., Alsum, S., Araújo, H.M., Bai, X., Balajthy, J., Beltrame, P., Bernard, E.P., Bernstein, A., Biesiadzinski, T.P., Boulton, E.M., B. Boxer, Brás, P., S. Burdin, Byram, D., Carmona-Benitez, M.C., Chan, C., Cutter, J.E., Davison, T.J.R., Druszkiewicz, E., Fallon, S.R., Fan, A., Fiorucci, S., Gaitskell, R.J., Genovesi, J., Ghag, C., Gilchriese, M.G.D., E. Grace, C. Gwilliam, Hall, C.R., Haselschwardt, S.J., Hertel, S.A., Hogan, D.P., Horn, M., Huang, D.Q., Ignarra, C.M., Jacobsen, R.G., Ji, W., Kamdin, K., Kazkaz, K., Khaitan, D., Knoche, R., E.V. Korolkova, S. Kravitz, V.A. Kudryavtsev, Lenardo, B.G., Lesko, K.T., Liao, J., J. Lin, Lindote, A., Lopes, M.I., Manalaysay, A., Mannino, R.L., Marangou, N., Marzioni, M.F., McKinsey, D.N., Mei, D.-M., Moongweluwan, M., Morad, J.A., Murphy, A.St.J., Nehrkorn, C., Nelson, H.N., Neves, F., Oliver-Mallory, K.C., Palladino, K.J., Pease, E.K., G. Rischbieter, Rhyne, C., P. Rossiter, Shaw, S., Shutt, T.A., Silva, C., Solmaz, M., Solovov, V.N., Sorensen, P., Sumner, T.J., Szydagis, M., Taylor, D.J., Taylor, W.C., Tennyson, B.P., Terman, P.A., Tiedt, D.R., To, W.H., Tripathi, M., Tvrznikova, L., Utku, U., Uvarov, S., Velan, V., Verbus, J.R., Webb, R.C., White, J.T., Whitis, T.J., Witherell, M.S., Wolfs, F.L.H., D. Woodward, Xu, J., Yazdani, K., Zhang, C.

“…The Large Underground Xenon experiment (LUX) searches for dark matter using a dual-phase xenon detector. LUX uses a custom-developed trigger system for event…”
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Ionization and scintillation of nuclear recoils in gaseous xenon by Renner, J., Gehman, V.M., Goldschmidt, A., Matis, H.S., Miller, T., Nakajima, Y., Nygren, D., Oliveira, C.A.B., Shuman, D., Álvarez, V., Borges, F.I.G., Cárcel, S., Castel, J., Cebrián, S., Cervera, A., Conde, C.A.N., Dafni, T., Dias, T.H.V.T., Díaz, J., Esteve, R., Evtoukhovitch, P., Fernandes, L.M.P., Ferrario, P., Ferreira, A.L., Freitas, E.D.C., Gil, A., Gómez, H., Gómez-Cadenas, J.J., González-Díaz, D., Gutiérrez, R.M., Hauptman, J., Hernando Morata, J.A., Herrera, D.C., Iguaz, F.J., Irastorza, I.G., Jinete, M.A., Labarga, L., Laing, A., Liubarsky, I., Lopes, J.A.M., Lorca, D., Losada, M., Luzón, G., Marí, A., Martín-Albo, J., Martínez, A., Moiseenko, A., Monrabal, F., Monserrate, M., Monteiro, C.M.B., Mora, F.J., Moutinho, L.M., Muñoz Vidal, J., Natal da Luz, H., Navarro, G., Nebot-Guinot, M., Palma, R., Pérez, J., Pérez Aparicio, J.L., Ripoll, L., Rodríguez, A., Rodríguez, J., Santos, F.P., dos Santos, J.M.F., Seguí, L., Serra, L., Simón, A., Sofka, C., Sorel, M., Toledo, J.F., Tomás, A., Torrent, J., Tsamalaidze, Z., Veloso, J.F.C.A., Villar, J.A., Webb, R.C., White, J., Yahlali, N.

“…Ionization and scintillation produced by nuclear recoils in gaseous xenon at approximately 14bar have been simultaneously observed in an electroluminescent…”
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Extracellular signal-regulated kinase (ERK) inhibition decreases arginase activity and improves corpora cavernosal relaxation in streptozotocin (STZ)-induced diabetic mice by Nunes, K.P., Toque, H.A., Caldwell, R.B., Caldwell, R.W., Webb, R.C.

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The effects of cyclopiazonic acid on intracellular Ca2+ in aortic smooth muscle cells from DOCA-hypertensive rats by Tostes, R C, Wilde, D W, Bendhack, L M, Webb, R C

“…We tested the hypothesis that cyclopiazonic acid (CPA), an inhibitor of the sarcoplasmic reticulum (SR) Ca(2+)-ATPase, increases intracellular Ca2+…”
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Tx2-6 toxin of the Phoneutria nigriventer spider potentiates rat erectile function by Nunes, K.P., Costa-Gonçalves, A., Lanza, L.F., Cortes, S.F., Cordeiro, M.N., Richardson, M., Pimenta, A.M.C., Webb, R.C., Leite, R., De Lima, M.E.

“…The venom of the spider Phoneutria nigriventer contains several toxins that have bioactivity in mammals and insects. Accidents involving humans are…”
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Results of the material screening program of the NEXT experiment by Dafni, T., Álvarez, V., Bandac, I., Bettini, A., Borges, F.I.G.M., Camargo, M., Cárcel, S., Cebrián, S., Cervera, A., Conde, C.A.N., Díaz, J., Esteve, R., Fernandes, L.M.P., Fernández, M., Ferrario, P., Ferreira, A.L., Freitas, E.D.C., Gehman, V.M., Goldschmidt, A., Gómez, H., Gómez-Cadenas, J.J., González-Díaz, D., Gutiérrez, R.M., Hauptman, J., Hernando Morata, J.A., Herrera, D.C., Iguaz, F.J., Irastorza, I.G., Labarga, L., Laing, A., Liubarsky, I., Lorca, D., Losada, M., Luzón, G., Marí, A., Martín-Albo, J., Martínez, A., Martínez-Lema, G., Miller, T., Monrabal, F., Monserrate, M., Monteiro, C.M.B., Mora, F.J., Moutinho, L.M., Muñoz Vidal, J., Nebot-Guinot, M., Nygren, D., Oliveira, C.A.B., Pérez, J., Pérez Aparicio, J.L., Renner, J., Ripoll, L., Rodríguez, A., Rodríguez, J., Santos, F.P., dos Santos, J.M.F., Segui, L., Serra, L., Shuman, D., Simón, A., Sofka, C., Sorel, M., Toledo, J.F., Torrent, J., Tsamalaidze, Z., Veloso, J.F.C.A., Villar, J.A., Webb, R.C., White, J.T., Yahlali, N.

“…The Neutrino Experiment with a Xenon TPC (NEXT), intended to investigate neutrinoless double beta decay, requires extremely low background levels. An extensive…”
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