Search Results - "Webb, G. C"

Identification and Characterization of New Inhibitors of the Escherichia coli MurA Enzyme by BAUM, Ellen Z, MONTENEGRO, Deborah A, LICATA, Lisa, TURCHI, Ignatius, WEBB, Glenda C, FOLENO, Barbara D, BUSH, Karen

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Substituted Salicylanilides as Inhibitors of Two-Component Regulatory Systems in Bacteria by Macielag, Mark J, Demers, James P, Fraga-Spano, Stephanie A, Hlasta, Dennis J, Johnson, Sigmond G, Kanojia, Ramesh M, Russell, Ronald K, Sui, Zhihua, Weidner-Wells, Michele A, Werblood, Harvey, Foleno, Barbara D, Goldschmidt, Raul M, Loeloff, Michael J, Webb, Glenda C, Barrett, John F

“…A new class of inhibitors of the two-component regulatory systems (TCS) of bacteria was discovered based on the salicylanilide screening hits, closantel (1)…”
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p53 cellular tumor antigen: analysis of mRNA levels in normal adult tissues, embryos, and tumors by ROGEL, A, POPLIKER, M, WEBB, C. G, OREN, M

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Molecular cloning of a cDNA and chromosomal localization of a human theta-class glutathione S-transferase gene ( GSTT2) to chromosome 22 by Tan, K.L., Webb, G.C., Baker, R.T., Board, P.G.

“…Until recently the Theta-class glutathione S-transferases (GSTs) were largely overlooked due to their low activity with the model substrate…”
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Molecular Organization of the Cytokine Gene Cluster, Involving the Human IL-3, IL-4, IL-5, and GM-CSF Genes, on Human Chromosome 5 by Leeuwen, B.H. van, Martinson, M.E., Webb, G.C., Young, I.G.

“…The human genes for the hematopoietic growth factors interleukin-3 (IL-3), IL-5, and granulocyte-macrophage col-ony-stimulating factor (GM-CSF) have been…”
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Isolation of a cDNA clone and localization of the human glutathione S-transferase 3 genes to chromosome bands 11q13 and 12q13-14 by Board, P G, Webb, G C, Coggan, M

“…A partial cDNA clone of the glutathione S-transferase 3 gene (GST3) was obtained by screening a lambda gt11 human lung cDNA library with antiserum to human…”
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The mouse homeobox gene, Gbx2 : Genomic organization and expression in pluripotent cells in vitro and in vivo by CHAPMAN, G, REMISZEWSKI, J. L, WEBB, G. C, SCHULZ, T. C, BOTTEMA, C. D. K, RATHJEN, P. D

“…The Gbx2 homeodomain is widely conserved in metazoans. We investigated the mouse Gbx2 locus by isolation and characterization of genomic clones and by physical…”
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Isolation of a cDNA Clone and Localization of Human Glutathione S-Transferase 2 Genes to Chromosome Band 6p12 by Philip G. Board, Webb, Graham C.

“…The glutathione S-transferases (GST) (glutathione transferase; EC 2.5.1.18) are a family of enzymes responsible for the metabolism of a broad range of…”
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Genetic Interactions Between a pep7 Mutation and the PEP12 and VPS45 Genes: Evidence for a Novel SNARE Component in Transport Between the Saccharomyces cerevisiae Golgi Complex and Endosome by Webb, G. C, Hoedt, M, Poole, L. J, Jones, E. W

“…The PEP7 gene from Saccharomyces cerevisiae encodes a 59-kD hydrophilic polypeptide that is required for transport of soluble vacuolar hydrolase precursors…”
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Novel inhibitors of bacterial two-component systems with gram positive antibacterial activity: Pharmacophore identification based on the screening hit closantel by Hlasta, Dennis J., Demers, James P., Foleno, Barbara D., Fraga-Spano, Stephanie A., Guan, Jihua, Hilliard, Jamese J., Macielag, Mark J., Ohemeng, Kwasi A., Sheppard, Cheryl M., Sui, Zhihua, Webb, Glenda C., Weidner-Wells, Michele A., Werblood, Harvey, Barrett, John F.

“…This SAR study has shown that the salicylanilide is the pharmacophore for inhibition of the bacterial two-component system. Hydrophobic substituents improve…”
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SAR studies of diaryltriazoles against bacterial two-component regulatory systems and their antibacterial activities by Sui, Zhihua, Guan, Jihua, Hlasta, Dennis J., Macielag, Mark J., Foleno, Barbara D., Goldschmidt, Raul M., Loeloff, Michael J., Webb, Glenda C., Barrett, John F.

“…A series of diaryltriazole analogs was discovered to inhibit bacterial two-component regulatory systems in our primary assays, KinA/SpoOF and NRII/NRI. They…”
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SOLH, a human homologue of the Drosophila melanogaster small optic lobes gene is a member of the calpain and zinc-finger gene families and maps to human chromosome 16p13.3 near CATM (cataract with microphthalmia) by KAMEI, M, WEBB, G. C, YOUNG, I. G, CAMPBELL, H. D

“…Mutations in the Drosophila melanogaster small optic lobes (sol) gene cause a sever reduction in the neuropiles of the medulla and lobula complexes of the…”
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Characterization of the EphA1 Receptor Tyrosine Kinase: Expression in Epithelial Tissues by Coulthard, Mark G., Lickliter, Jason D., Subanesan, Nadesapillai, Chen, Ke, Webb, Graham C., Lowry, Amanda J., Koblar, Simon, Bottema, Cynthia D.K., Boyd, Andrew W.

“…Abstract The Eph family of receptor tyrosine kinases plays a crucial role during development and is implicated in oncogenesis. Using a partial cDNA clone of an…”
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Expression profiling of pancreatic beta-cells: glucose regulation of secretory and metabolic pathway genes by WEBB, Gene C, AKBAR, Murtaza S, CHONGJIAN ZHAO, STEINER, Donald F

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Chromosomal mapping of the human Mu class glutathione S-transferases to 1p13 by Ross, V L, Board, P G, Webb, G C

“…The chromosomal localization of the human Mu class glutathione S-transferase (GST) genes has been complicated by two factors; the total number of genes is…”
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Structure of the 5' flanking region of the gene encoding human parathyroid-hormone-related protein (PTHrP) by Suva, L J, Mather, K A, Gillespie, M T, Webb, G C, Ng, K W, Winslow, G A, Wood, W I, Martin, T J, Hudson, P J

“…We have characterized a human genomic clone that contains the 5' coding and 5' flanking sequences of the human parathyroid hormone-related protein gene…”
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The gene encoding human glutathione synthetase (GSS) maps the long arm of chromosome 20 at band 11.2 by WEBB, G. C, VASKA, V. L, GALI, R. R, FORD, J. H, BOARD, P. G

“…Two forms of glutathione synthetase deficiency have been described. While one form is mild, causing hemolytic anemia, the other more severe form causes…”
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Characterization of a cDNA and Gene Encoding the Mouse Theta Class Glutathione Transferase mGSTT2 and Its Localization to Chromosome 10B5–C1 by Whittington, A.T., Webb, G.C., Baker, R.T., Board, P.G.

“…In this study, we have isolated and characterized a gene and cDNA encoding a mouse Theta class GST. The gene,mGSTT2,spans approximately 3.1 kb and is composed…”
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Physical mapping of the stearoyl-CoA desaturase (SCD) locus in sheep by Kuchel, H., Siebert, B. D., Bottema, C. D. K., Webb, G. C., Crawford, A. M., Duncan, S. J., McDonald, P. A., McEwan, J. C., Pitchford, W. S.

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Genetic variability at the human tumor necrosis factor loci by Webb, GC, Chaplin, DD

“…Variability in the structure of the human tumor necrosis factor (TNF-alpha) or lymphotoxin (TNF-beta) genes may contribute to the functional polymorphism of…”
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