Search Results - "Webb, Andrew E."
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Insights into the Evolution of Longevity from the Bowhead Whale Genome
Published in Cell reports (Cambridge) (06-01-2015)“…The bowhead whale (Balaena mysticetus) is estimated to live over 200 years and is possibly the longest-living mammal. These animals should possess protective…”
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Return to the Sea, Get Huge, Beat Cancer: An Analysis of Cetacean Genomes Including an Assembly for the Humpback Whale (Megaptera novaeangliae)
Published in Molecular biology and evolution (01-08-2019)“…Cetaceans are a clade of highly specialized aquatic mammals that include the largest animals that have ever lived. The largest whales can have ∼1,000× more…”
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NAPS: Integrating pose estimation and tag-based tracking
Published in Methods in ecology and evolution (01-10-2023)“…1. Significant advances in computational ethology have allowed the quantification of behaviour in unprecedented detail. Tracking animals in social groups,…”
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Erratum to: Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response
Published in BMC evolutionary biology (12-06-2017)“…“Upon publication of the original article [1], it was noticed that there was an error in the author name. The author’s name should be "Micheal Mac Aogain"…”
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VESPA: Very large-scale Evolutionary and Selective Pressure Analyses
Published in PeerJ. Computer science (05-06-2017)“…Large-scale molecular evolutionary analyses of protein coding sequences requires a number of preparatory inter-related steps from finding gene families, to…”
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Developmental transcriptomes predict adult social behaviours in the socially flexible sweat bee, Lasioglossum baleicum
Published in Molecular ecology (18-12-2023)“…Natural variation can provide important insights into the genetic and environmental factors that shape social behaviour and its evolution. The sweat bee,…”
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Heterogeneous models place the root of the placental mammal phylogeny
Published in Molecular biology and evolution (01-09-2013)“…Heterogeneity among life traits in mammals has resulted in considerable phylogenetic conflict, particularly concerning the position of the placental root…”
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Adaptive Evolution as a Predictor of Species-Specific Innate Immune Response
Published in Molecular biology and evolution (01-07-2015)“…It has been proposed that positive selection may be associated with protein functional change. For example, human and macaque have different outcomes to HIV…”
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Adaptive Evolution in TRIF Leads to Discordance between Human and Mouse Innate Immune Signaling
Published in Genome biology and evolution (01-12-2021)“…Abstract The TIR domain-containing adapter inducing IFN-β (TRIF) protein is an innate immune system protein that mediates the MyD88-independent toll-like…”
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Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response
Published in BMC evolutionary biology (23-03-2017)“…Clostridium difficile is a nosocomial pathogen prevalent in hospitals worldwide and increasingly common in the community. Sequence differences have been shown…”
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Convergent and complementary selection shaped gains and losses of eusociality in sweat bees
Published in Nature ecology & evolution (01-04-2023)“…Sweat bees have repeatedly gained and lost eusociality, a transition from individual to group reproduction. Here we generate chromosome-length genome…”
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Gene Fusions Derived by Transcriptional Readthrough are Driven by Segmental Duplication in Human
Published in Genome biology and evolution (01-09-2019)“…Gene fusion occurs when two or more individual genes with independent open reading frames becoming juxtaposed under the same open reading frame creating a new…”
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Repeated Shifts in Sociality Are Associated With Fine-tuning of Highly Conserved and Lineage-Specific Enhancers in a Socially Flexible Bee
Published in Molecular biology and evolution (01-11-2024)“…Comparative genomic studies of social insects suggest that changes in gene regulation are associated with evolutionary transitions in social behavior, but the…”
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Return to the sea, get huge, beat cancer: an analysis of cetacean genomes including an asssembly for the humpback whale (megaptera novaeangliae)
Published in Molecular biology and evolution (2019)“…Cetaceans are a clade of highly specialized aquatic mammals that include the largest animals that have ever lived. The largest whales can have ∼1,000× more…”
Get full text
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Ca^2+ signaling during vertebrate somitogenesis
Published in Acta pharmacologica Sinica (2006)“…A variety of Ca^2+ signals, in the form of intercellular pulses and waves, have been reported to be associated with the various sequential stages of…”
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Expression and reconstitution of the bioluminescent Ca2+ reporter aequorin in human embryonic stem cells, and exploration of the presence of functional IP3 and ryanodine receptors during the early stages of their differentiation into cardiomyocytes
Published in Science China. Life sciences (01-08-2016)“…In order to develop a novel method of visualizing possible Ca2+ signaling during the early differentiation of hESCs into cardi- omyocytes and avoid some of the…”
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