Search Results - "Weaver, T. E."
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1
Efficacy of the topical nasal steroid budesonide on improving sleep and daytime somnolence in patients with perennial allergic rhinitis
Published in Allergy (Copenhagen) (01-05-2003)“…Background: Improving quality of life is considered to be a major endpoint and motivation for clinical intervention in patients with perennial allergic…”
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An instrument to measure functional status outcomes for disorders of excessive sleepiness
Published in Sleep (New York, N.Y.) (01-10-1997)“…This article reports the development of the functional outcomes of sleep questionnaire (FOSQ). This is the first self-report measure designed to assess the…”
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Function and regulation of expression of pulmonary surfactant-associated proteins
Published in Biochemical journal (15-01-1991)Get full text
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Human surfactant protein B: structure, function, regulation, and genetic disease
Published in Physiological reviews (01-10-1995)“…Elucidation of the structure and function of the hydrophobic surfactant protein (SP-B) and the SP-B gene has provided critical insight into surfactant…”
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Association of peri‐operative prescription of non‐steroidal anti‐inflammatory drugs with continued prescription of opioids after total knee arthroplasty: a retrospective claims‐based cohort study
Published in Anaesthesia (01-07-2024)“…Summary Non‐steroidal anti‐inflammatory drugs (NSAIDs) are one of the mainstays of multimodal pain management. While effective for acute pain control, recent…”
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Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice
Published in Proceedings of the National Academy of Sciences - PNAS (15-08-1995)“…Surfactant protein B (SP-B) is an 8.7-kDa, hydrophobic protein that enhances the spreading and stability of surfactant phospholipids in the alveolus. To…”
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7
Outcome measurement in sleep medicine practice and research. Part 2: assessment of neurobehavioral performance and mood
Published in Sleep Medicine Reviews (01-06-2001)“…Neurobehavioral performance and alterations in mood consequent to sleep disorders and their treatment has recently been the focus of clinical investigations…”
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Book Review Journal Article -
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Bacterial Killing Is Enhanced by Expression of Lysozyme in the Lungs of Transgenic Mice
Published in The Journal of immunology (1950) (15-11-2000)“…To assess the role of lysozyme in pulmonary host defense in vivo, transgenic mice expressing rat lysozyme cDNA in distal respiratory epithelial cells were…”
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Night-to-night variability in CPAP use over the first three months of treatment
Published in Sleep (New York, N.Y.) (01-04-1997)“…The purpose of this study was to examine the relationship between night-to-night variability and nightly duration of continuous positive airway pressure (CPAP)…”
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10
Proteolytic generation and aggregation of peptides from transmembrane regions: lung surfactant protein C and amyloid beta-peptide
Published in Cellular and molecular life sciences : CMLS (01-02-2004)“…The formation of amyloid fibrils is associated with several devastating diseases in humans and animals, including e.g. Alzheimer's disease (AD) and the…”
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Bacterial killing is enhanced by exogenous administration of lysozyme in the lungs
Published in Respiratory medicine and research (01-11-2019)“…Lysozyme, a 14-kDa protein, is one of the most abundant antimicrobials in the lungs. Its concentration in airway surface sufficient to kill several bacterial…”
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Lamellar Body Formation in Normal and Surfactant Protein B-Deficient Fetal Mice
Published in Laboratory investigation (01-03-2000)“…Surfactant protein B (SP-B) −/− mice die of lethal respiratory distress syndrome shortly after birth. Alveolar type II epithelial cells in SP-B–deficient mice…”
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Journal Article Conference Proceeding -
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Intracellular processing of pulmonary surfactant protein B in an endosomal/lysosomal compartment
Published in The American journal of physiology (01-10-1992)“…The hydrophobic surfactant protein B (SP-B) is synthesized in alveolar type II cells as a 40-kDa precursor protein that is processed via 39- and 23-kDa…”
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Neurobehavioral consequences of arousals
Published in Sleep (New York, N.Y.) (01-12-1996)“…The neurobehavioral deficits of obstructive sleep apnea syndrome (OSAS) are often attributed to the rate of respiratory disturbance or rate of arousals during…”
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Conference Proceeding Journal Article -
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Posttranslational processing of surfactant protein C in rat type II cells
Published in The American journal of physiology (01-12-1995)“…Pulmonary surfactant consists of phospholipids and proteins that form a stable monolayer at the surface of the alveoli to prevent lung collapse. Surfactant…”
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16
Processing of surfactant protein B proprotein by a cathepsin D-like protease
Published in The American journal of physiology (01-07-1992)“…Surfactant protein B (SP-B) is a hydrophobic peptide of relative molecular weight (M(r)) = 8,000 that is associated with pulmonary surfactant phospholipids…”
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Differential effects of epidermal growth factor and transforming growth factor-beta on synthesis of Mr = 35,000 surfactant-associated protein in fetal lung
Published in The Journal of biological chemistry (05-06-1987)“…Differentiation of pulmonary Type II epithelial cells in late gestation is associated with the synthesis of pulmonary surfactant required for adaptation to air…”
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Adherence to continuous positive airway pressure therapy: the challenge to effective treatment
Published in Proceedings of the American Thoracic Society (15-02-2008)“…Despite the high efficacy of continuous positive airway pressure (CPAP) to reverse upper airway obstruction in sleep apnea, treatment effectiveness is limited…”
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19
Single-step purification/solubilization of recombinant proteins: application to surfactant protein B
Published in BioTechniques (01-05-1996)Get full text
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cDNA, deduced polypeptide structure and chromosomal assignment of human pulmonary surfactant proteolipid, SPL(pVal)
Published in The Journal of biological chemistry (05-01-1988)“…In hyaline membrane disease of premature infants, lack of surfactant leads to pulmonary atelectasis and respiratory distress. Hydrophobic surfactant proteins…”
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