Search Results - "Weaver, Simon"
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Preparative capillary electrophoresis (CE) fractionation of protein digests improves protein and peptide identification in bottom-up proteomics
Published in Analytical methods (17-03-2022)“…Reversed-phase liquid chromatography (RPLC) is widely used to reduce sample complexity prior to mass spectrometry (MS) analysis in bottom-up proteomics…”
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PrIntMap-R: An Online Application for Intraprotein Intensity and Peptide Visualization from Bottom-Up Proteomics
Published in Journal of proteome research (03-02-2023)“…Bottom-up proteomics (BUP) produces rich data, but visualization and analysis are time-consuming and often require programming skills. Many tools analyze these…”
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Activity: Teaching Coding in R through Discipline-Focused Problem-Solving in an Analytical Chemistry Course
Published in Journal of chemical education (09-08-2022)“…Students completing undergraduate majors in chemistry are not typically required to undergo formal training in computer programming or coding. As a result,…”
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An N-acetyltransferase required for ESAT-6 N-terminal acetylation and virulence in Mycobacterium marinum
Published in mBio (31-10-2023)“…N-terminal acetylation is a protein modification that broadly impacts basic cellular function and disease in higher organisms. Although bacterial proteins are…”
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Characterization of DNA aptamer-protein binding using fluorescence anisotropy assays in low-volume, high-efficiency plates
Published in Analytical methods (18-03-2021)“…Aptamers have many useful attributes including specific binding to molecular targets. After aptamers are identified, their target binding must be…”
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A Revised Molecular Model of Ovarian Cancer Biomarker CA125 (MUC16) Enabled by Long-read Sequencing
Published in Cancer research communications (31-01-2024)“…The biomarker CA125, a peptide epitope located in several tandem repeats of the mucin MUC16, is the gold standard for monitoring regression and recurrence of…”
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The loss of the PDIM/PGL virulence lipids causes differential secretion of ESX-1 substrates in Mycobacterium marinum
Published in mSphere (29-05-2024)“…The mycobacterial cell envelope is a major virulence determinant in pathogenic mycobacteria. Specific outer lipids play roles in pathogenesis, modulating the…”
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N-terminal proteomics of Mycobacterium marinum using bottom-up label-free quantitative analysis in data-dependent acquisition mode on a timsTOF Pro mass spectrometer
Published in Microbiology resource announcements (11-04-2024)“…N-terminal acetylation in is correlated with pathogenic activity. We used genomics and bottom-up proteomics to identify protein Emp1 as the sole…”
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Simultaneous N‑Deglycosylation and Digestion of Complex Samples on S‑Traps Enables Efficient Glycosite Hypothesis Generation
Published in ACS omega (31-01-2023)“…N-linked glycosylation is an important post-translational modification that is difficult to identify and quantify in traditional bottom-up proteomics…”
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A rhetorical discourse analysis of online anti-Muslim and anti-Semitic jokes
Published in Ethnic and racial studies (01-03-2013)“…Constructed with linguistic devices that resemble metaphor and other rhetorical devices, humour has the inbuilt ability to support racism in various readings…”
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Editorial for special issue on education and humour: Education and humour as tools for social awareness and critical consciousness in contemporary classrooms
Published in European journal of humour research (01-11-2015)“…This is a collection of international papers on the roles that humour can play in education. It brings together authors from Australia, Canada, Colombia, the…”
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The 'Other' Laughs Back: Humour and Resistance in Anti-racist Comedy
Published in Sociology (Oxford) (01-02-2010)“…This article outlines the 'reverse discourses' of black, African-American and Afro-Caribbean comedians in the UK and USA. These reverse discourses appear in…”
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On the importance of the dynamics of humour and comedy for constructionism and reflexivity in social science research methodology
Published in International journal of social research methodology (03-09-2022)“…Humour and comedy have gained increased significance in academic research in recent years. This article examines the importance of humour and comedy as…”
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Jokes, rhetoric and embodied racism: a rhetorical discourse analysis of the logics of racist jokes on the internet
Published in Ethnicities (01-12-2011)“…This article outlines the racist rhetoric employed in anti-black jokes on five internet websites. It is argued that racist jokes can act as important…”
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Institutional Complexity and Individual Responses: Delineating the Boundaries of Partial Autonomy
Published in Organization studies (01-01-2017)“…Research highlights how coexisting institutional logics can sometimes offer opportunities for agency to enterprising actors in organizational fields. But…”
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A qualitative study of families of a child with a nut allergy
Published in Chronic illness (01-12-2011)“…Objectives: The aim of this study was to explore, using qualitative methods, the experiences of children and their parents living with nut allergy. Methods:…”
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Liquid racism and the ambiguity of Ali G
Published in European journal of cultural studies (01-06-2011)“…This article analyses Ali G through the concept of ‘liquid racism’. As a polysemic and elusive form, liquid racism requires reflexivity in order to critique it…”
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Liquid Racism and the Danish Prophet Muhammad Cartoons
Published in Current sociology (01-09-2010)“…This article examines reactions to the October 2005 publication of the Prophet Muhammad cartoons in the Danish newspaper Jyllands-Posten. It does so by using…”
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Developing a rhetorical analysis of racist humour: examining anti-black jokes on the Internet
Published in Social semiotics (01-11-2010)“…Racist humour is frequently the subject of media and public debate in relation to issues of offence and acceptability. Despite this, little has been done to…”
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