Search Results - "Weaver, Samantha R"

Elevating serotonin pre-partum alters the Holstein dairy cow hepatic adaptation to lactation by Weaver, Samantha R, Prichard, Allan S, Maerz, Noah L, Prichard, Austin P, Endres, Elizabeth L, Hernández-Castellano, Lorenzo E, Akins, Matthew S, Bruckmaier, Rupert M, Hernandez, Laura L

“…Serotonin is known to regulate energy and calcium homeostasis in several mammalian species. The objective of this study was to determine if pre-partum…”
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Impact of Fluoxetine Treatment and Folic Acid Supplementation on the Mammary Gland Transcriptome During Peak Lactation by Sheftel, Celeste M, Liu, Lihe, Field, Sena L, Weaver, Samantha R, Vezina, Chad M, Peñagaricano, Francisco, Hernandez, Laura L

“…Serotonin is a key regulator of mammary gland homeostasis during lactation. Selective serotonin reuptake inhibitors (SSRIs) are commonly used to treat…”
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Elevated serotonin coordinates mammary metabolism in dairy cows by Connelly, Meghan K., Weaver, Samantha R., Kuehnl, Jordan M., Fricke, Hannah P., Klister, Marisa, Hernandez, Laura

“…Serotonin plays a diverse role in maternal and mammary metabolism. Recent research in the dairy cow has shown a relationship between serotonin and calcium,…”
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Serotonin Deficiency Rescues Lactation on Day 1 in Mice Fed a High Fat Diet by Weaver, Samantha R, Bohrer, Justin C, Prichard, Allan S, Perez, Paola K, Streckenbach, Liana J, Olson, Jake M, Cook, Mark E, Hernandez, Laura L

“…Obesity is an inflammatory state associated with delayed lactogenesis stage II and altered mammary gland morphology. Serotonin mediates inflammation and…”
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Phlpp1 alters the murine chondrocyte phospho-proteome during endochondral bone formation by Weaver, Samantha R., Peralta-Herrera, Eduardo, Torres, Haydee M., Jessen, Erik, Bradley, Elizabeth W., Westendorf, Jennifer J.

“…Appendicular skeletal growth and bone mass acquisition are controlled by a variety of growth factors, hormones, and mechanical forces in a dynamic process…”
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Inhibition of Phlpp1 preserves the mechanical integrity of articular cartilage in a murine model of post-traumatic osteoarthritis by Arnold, Katherine M., Weaver, Samantha R., Zars, Elizabeth L., Tschumperlin, Daniel J., Westendorf, Jennifer J.

“…Phlpp1 inhibition is a potential therapeutic strategy for cartilage regeneration and prevention of post-traumatic osteoarthritis (PTOA). To understand how…”
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Inflammatory Processes Affecting Bone Health and Repair by Torres, Haydee M., Arnold, Katherine M., Oviedo, Manuela, Westendorf, Jennifer J., Weaver, Samantha R.

“…Purpose of Review The purpose of this article is to review the current understanding of inflammatory processes on bone, including direct impacts of…”
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Pleckstrin homology (PH) domain and Leucine Rich Repeat Phosphatase 1 (Phlpp1) Suppresses Parathyroid Hormone Receptor 1 (Pth1r) Expression and Signaling During Bone Growth by Weaver, Samantha R, Taylor, Earnest L, Zars, Elizabeth L, Arnold, Katherine M, Bradley, Elizabeth W, Westendorf, Jennifer J

“…ABSTRACT Endochondral ossification is tightly controlled by a coordinated network of signaling cascades including parathyroid hormone (PTH). Pleckstrin…”
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Could use of Selective Serotonin Reuptake Inhibitors During Lactation Cause Persistent Effects on Maternal Bone? by Weaver, Samantha R., Hernandez, Laura L.

“…The lactating mammary gland elegantly coordinates maternal homeostasis to provide calcium for milk. During lactation, the monoamine serotonin regulates the…”
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Pleckstrin homology (PH) domain and leucine rich repeat phosphatase 1 (Phlpp1) suppresses parathyroid hormone receptor 1 (Pth1r) expression and signaling during bone growth by Weaver, Samantha R., Taylor, Earnest L., Zars, Elizabeth L., Arnold, Katherine M., Bradley, Elizabeth W., Westendorf, Jennifer J.

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Peripartum Fluoxetine Reduces Maternal Trabecular Bone After Weaning and Elevates Mammary Gland Serotonin and PTHrP by Weaver, Samantha R, Fricke, Hannah P, Xie, Cynthia, Lipinski, Robert J, Vezina, Chad M, Charles, Julia F, Hernandez, Laura L

“…Abstract Selective serotonin reuptake inhibitors (SSRIs) have been linked to osteopenia and fracture risk; however, their long-term impact on bone health is…”
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GIRK3 deletion facilitates kappa opioid signaling in chondrocytes, delays vascularization and promotes bone lengthening in mice by Taylor, Earnest L., Weaver, Samantha R., Lorang, Ian M., Arnold, Katherine M., Bradley, Elizabeth W., Marron Fernandez de Velasco, Ezequiel, Wickman, Kevin, Westendorf, Jennifer J.

“…Long bones are formed and repaired through the process of endochondral ossification. Activation of G protein-coupled receptor (GPCR) signaling pathways is…”
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In utero and lactational exposure to the Selective Serotonin Reuptake Inhibitor fluoxetine compromises pup bones at weaning by Weaver, Samantha R., Xie, Cynthia, Charles, Julia F., Hernandez, Laura L.

“…Selective Serotonin Reuptake Inhibitors (SSRIs) such as fluoxetine are widely prescribed to pregnant and breastfeeding women, yet the effects of peripartum…”
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Characterization of mammary-specific disruptions for Tph1 and Lrp5 during murine lactation by Weaver, Samantha R., Jury, Nicholas J., Gregerson, Karen A., Horseman, Nelson D., Hernandez, Laura L.

“…Serotonin is a homeostatic regulator of the mammary gland during lactation. The contribution of mammary-derived serotonin to circulating serum serotonin…”
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Increasing serotonin concentrations alter calcium and energy metabolism in dairy cows by Laporta, Jimena, Moore, Spencer A E, Weaver, Samantha R, Cronick, Callyssa M, Olsen, Megan, Prichard, Austin P, Schnell, Brian P, Crenshaw, Thomas D, Peñagaricano, Francisco, Bruckmaier, Rupert M, Hernandez, Laura L

“…A 4×4 Latin square design in which varied doses (0, 0.5, 1.0, and 1.5 mg/kg) of 5-hydroxy-l-tryptophan (5-HTP, a serotonin precursor) were intravenously…”
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Elevation of circulating serotonin improves calcium dynamics in the peripartum dairy cow by Weaver, Samantha R, Prichard, Austin P, Endres, Elizabeth L, Newhouse, Stefanie A, Peters, Tonia L, Crump, Peter M, Akins, Matthew S, Crenshaw, Thomas D, Bruckmaier, Rupert M, Hernandez, Laura L

“…Hypocalcemia is a metabolic disorder that affects dairy cows during the transition from pregnancy to lactation. Twelve multiparous Holstein cows and twelve…”
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Serotonin Regulates Calcium Homeostasis in Lactation by Epigenetic Activation of Hedgehog Signaling by Laporta, Jimena, Keil, Kimberly P, Weaver, Samantha R, Cronick, Callyssa M, Prichard, Austin P, Crenshaw, Thomas D, Heyne, Galen W, Vezina, Chad M, Lipinski, Robert J, Hernandez, Laura L

“…Calcium homeostasis during lactation is critical for maternal and neonatal health. We previously showed that nonneuronal/peripheral serotonin…”
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Peripartum dietary supplementation of a small-molecule inhibitor of tryptophan hydroxylase 1 compromises infant, but not maternal, bone by Weaver, Samantha R, Fricke, Hannah P, Xie, Cynthia, Aiello, Robert J, Charles, Julia F, Hernandez, Laura L

“…Long-term effects of breastfeeding on maternal bone are not fully understood. Excessive maternal bone loss stimulated by serotonin signaling during lactation…”
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Effect of induced hypocalcemia in nonlactating, nonpregnant Holstein cows fed negative DCAD with low, medium, or high concentrations of calcium by Amundson, Laura A, Rowson, Angela D, Crump, Peter M, Prichard, Austin P, Cheng, Adrienne A, Wimmler, Collin E, Klister, Marisa, Weaver, Samantha R, Bascom, Scott S, Nuzback, Dennis E, Zanzalari, Ken P, Hernandez, Laura L

“…Abstract The main objective of this study was to determine how feeding different dietary calcium (Ca) concentrations in combination with a negative dietary…”
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Girk3 deletion increases osteoblast maturation and bone mass accrual in adult male mice by Weaver, Samantha R, Torres, Haydee M, Arnold, Katherine M, Zars, Elizabeth L, Peralta-Herrera, Eduardo, Taylor, Earnest L, Yu, Kanglun, Marron Fernandez de Velasco, Ezequiel, Wickman, Kevin, McGee-Lawrence, Meghan E, Bradley, Elizabeth W, Westendorf, Jennifer J

“…Osteoporosis and other metabolic bone diseases are prevalent in the aging population. While bone has the capacity to regenerate throughout life, bone formation…”
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