Search Results - "Weaver, Michael R."
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MnTE-2-PyP reduces prostate cancer growth and metastasis by suppressing p300 activity and p300/HIF-1/CREB binding to the promoter region of the PAI-1 gene
Published in Free radical biology & medicine (01-05-2016)“…To improve radiation therapy-induced quality of life impairments for prostate cancer patients, the development of radio-protectors is needed. Our previous work…”
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FABP5 deficiency enhances susceptibility to H1N1 influenza A virus-induced lung inflammation
Published in American journal of physiology. Lung cellular and molecular physiology (01-07-2013)“…The early inflammatory response to influenza A virus infection contributes to severe lung disease and continues to pose a serious threat to human health. The…”
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Impact of fatty acid binding protein 5-deficiency on COPD exacerbations and cigarette smoke-induced inflammatory response to bacterial infection
Published in Clinical and translational medicine (15-03-2019)“…Background Although cigarette smoking (CS) is by far the most important risk factor of chronic obstructive pulmonary disease (COPD), repeated and sustained…”
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Effect of pH on the Structure and Dynamics of Wormlike Micelles in an Amino Acid-Derived Surfactant Composition
Published in Langmuir (13-04-2021)“…We studied the impact of pH as a thickening mechanism on the structure and dynamics of wormlike micelles in a mixture of sodium lauroyl sarcosinate (SLSar) and…”
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Schwann cell interactions during the development of the peripheral nervous system
Published in Developmental neurobiology (Hoboken, N.J.) (01-07-2021)“…Schwann cells play a critical role in the development of the peripheral nervous system (PNS), establishing important relationships both with the extracellular…”
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The metalloporphyrin antioxidant, MnTE-2-PyP, inhibits Th2 cell immune responses in an asthma model
Published in International journal of molecular sciences (01-08-2012)“…MnTE-2-PyP, a superoxide dismutase mimetic, inhibited OVA-induced airway inflammation in mice suggesting an effect on Th2 responsiveness. Thus, we hypothesized…”
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The Hippo pathway: Horizons for innovative treatments of peripheral nerve diseases
Published in Journal of the peripheral nervous system (01-03-2021)“…Initially identified in Drosophila, the Hippo signaling pathway regulates how cells respond to their environment by controlling proliferation, migration and…”
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MnTE‐2‐PyP disrupts Staphylococcus aureus biofilms in a novel fracture model
Published in Journal of orthopaedic research (01-11-2021)“…Biofilm‐associated infections in orthopedic surgery lead to worse clinical outcomes and greater morbidity and mortality. The scope of the problem encompasses…”
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Impact of Acellular Dermal Matrix on Postsurgical Wound Fluid Biomarkers in Prosthetic Breast Reconstruction
Published in Annals of plastic surgery (01-12-2018)“…BACKGROUNDDespite the widespread practice of using biologic scaffolds for soft tissue reinforcement over prosthetic implants, the impact of acellular dermal…”
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An oxidative environment promotes growth of Mycobacterium abscessus
Published in Free radical biology & medicine (01-12-2010)“…Mycobacterium abscessus infections, particularly those causing chronic lung diseases, are becoming more prevalent worldwide. M. abscessus infections are…”
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Endogenous enzymes (NOX and ECSOD) regulate smoke-induced oxidative stress
Published in Free radical biology & medicine (15-12-2010)“…Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the United States and the incidence is increasing as the population ages…”
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A Common Polymorphism in Extracellular Superoxide Dismutase Affects Cardiopulmonary Disease Risk by Altering Protein Distribution
Published in Circulation. Cardiovascular genetics (01-10-2014)“…BACKGROUND—The enzyme extracellular superoxide dismutase (EC-SOD; SOD3) is a major antioxidant defense in lung and vasculature. A nonsynonomous…”
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The R213G polymorphism in SOD3 protects against allergic airway inflammation
Published in JCI insight (07-09-2017)“…Oxidative stress is important in the pathogenesis of allergic asthma. Extracellular superoxide dismutase (EC-SOD; SOD3) is the major antioxidant in lungs, but…”
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Anticipating colloidal instabilities in cationic vesicle dispersions by measuring collective motions with dynamic light scattering
Published in Journal of colloid and interface science (15-04-2006)“…Vesicle dispersions are useful for many applications from medicinal to consumer products. However, using these dispersions requires some knowledge of and…”
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MnTE‐2‐PyP disrupts S taphylococcus aureus biofilms in a novel fracture model
Published in Journal of orthopaedic research (01-11-2021)“…Abstract Biofilm‐associated infections in orthopedic surgery lead to worse clinical outcomes and greater morbidity and mortality. The scope of the problem…”
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23 - MnTE-2-PyP Inhibits Prostate Tumor Growth and Metastasis by Inhibiting p300 Activity
Published in Free radical biology & medicine (01-11-2013)Get full text
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MnTE-2-PyP Inhibits Prostate Tumor Growth and Metastasis by Inhibiting p300 Activity
Published in Free radical biology & medicine (01-11-2013)Get full text
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The SOD Mimetic, MnTE-2-PyP, Inhibits Prostate Tumor Growth and Metastasis
Published in Free radical biology & medicine (01-11-2012)Get full text
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