Search Results - "Weaver, J U"

Circulating endothelial progenitor cells, endothelial function, carotid intima-media thickness and circulating markers of endothelial dysfunction in people with type 1 diabetes without macrovascular disease or microalbuminuria by Sibal, L, Aldibbiat, A, Agarwal, S. C, Mitchell, G, Oates, C, Razvi, S, Weaver, J. U, Shaw, J. A, Home, P. D

“…Aims/hypothesis Type 1 diabetes is associated with premature arterial disease. Bone-marrow derived, circulating endothelial progenitor cells (EPCs) are…”
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Severe hyponatraemia: investigation and management in a district general hospital by Saeed, B O, Beaumont, D, Handley, G H, Weaver, J U

“…Aims: To study the incidence, investigation, and management of severe hyponatraemia (serum sodium < 120 mmol/litre) over a period of six months in a district…”
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The effect of low dose recombinant human growth hormone replacement on regional fat distribution, insulin sensitivity, and cardiovascular risk factors in hypopituitary adults by Weaver, J U, Monson, J P, Noonan, K, John, W G, Edwards, A, Evans, K A, Cunningham, J

“…GH deficiency is associated with increased cardiovascular morbidity, which may be determined by alterations in vascular risk factors. We report the effect of…”
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The influence of gender on the short and long-term effects of growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults: a 5-year study by Drake, W. M., Rodríguez-Arnao, J., Weaver, J. U., James, I. T., Coyte, D., Spector, T. D., Besser, G. M., Monson, J. P.

“…OBJECTIVES The objectives of this study were to investigate the effects of GH replacement therapy in hypopituitary adults with growth hormone deficiency (GHD)…”
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Design of new questionnaires to measure quality of life and treatment satisfaction in hypothyroidism by McMillan, C V, Bradley, C, Woodcock, A, Razvi, S, Weaver, J U

“…This paper reports work undertaken to design two new condition-specific questionnaires for use in hypothyroidism: the Underactive Thyroid-Dependent Quality of…”
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Serum fructosamine as a marker of 5-year risk of developing diabetes mellitus in patients exhibiting stress hyperglycaemia by Wahid, S. T., Sultan, J., Handley, G., Saeed, B. O., Weaver, J. U., Robinson, A. C. J.

“…Aims We examined whether the level of random serum glucose (RSG) in subjects exhibiting stress hyperglycaemia is a useful marker of the future risk of…”
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Appropriate insulin regimes for type 2 diabetes: a multicenter randomized crossover study by TAYLOR, Roy, DAVIES, Robert, FOX, Charles, SAMPSON, Michael, WEAVER, Jola U, WOOD, Linda

“…Appropriate insulin regimes for type 2 diabetes: a multicenter randomized crossover study. R Taylor , R Davies , C Fox , M Sampson , J U Weaver and L Wood…”
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Sexual dimorphism in 11 β hydroxysteroid dehydrogenase activity and its relation to fat distribution and insulin sensitivity; a study in hypopituitary subjects by Weaver, Jolanta U, Taylor, Norman F, Monson, John P, Wood, Peter J, Kelly, William F

“…OBJECTIVE Sexual dimorphism of 11 β hydroxysteroid dehydrogenase activity (11 β HSD) as measured by the urinary 11‐OH/11‐oxo cortisol metabolite ratio has been…”
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Influence of growth hormone on accretion of bone mass by Monson, J P, Drake, W M, Carroll, P V, Weaver, J U, Rodriguez-Arnao, J, Savage, M O

“…Growth hormone (GH) exerts important influences on bone metabolism during lifespan. During childhood, GH is a major determinant of acquisition of bone mass and…”
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Nateglinide alone or with metformin safely improves glycaemia to target in patients up to an age of 84 by Weaver, J. U., Robertson, D., Atkin, S. L.

“…Aim:  To assess the effect of nateglinide on efficacy [fasting plasma glucose (FPG), postprandial plasma glucose (PPG) plasma glucose and HbA1c], tolerability…”
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Randomized controlled trial to assess the impact of continuous glucose monitoring on HbA1c in insulin-treated diabetes (MITRE Study) by Cooke, D., Hurel, S. J., Casbard, A., Steed, L., Walker, S., Meredith, S., Nunn, A. J., Manca, A., Sculpher, M., Barnard, M., Kerr, D., Weaver, J. U., Ahlquist, J., Newman, S. P.

“…Aims  To determine whether continuous glucose information provided through use of either the GlucoWatch G2 Biographer or the MiniMed continuous glucose…”
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Central obesity and hyperinsulinaemia in women are associated with polymorphism in the 5' flanking region of the human insulin gene by Weaver, J U, Kopelman, P G, Hitman, G A

“…Obesity is a multifactorial disease with a marked genetic component. The situation is further complicated by the heterogeneity of obesity demonstrated by the…”
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Decreased sex hormone binding globulin (SHBG) and insulin-like growth factor binding protein (IGFBP-1) in extreme obesity by Weaver, J U, Holly, J M, Kopelman, P G, Noonan, K, Giadom, C G, White, N, Virdee, S, Wass, J A

“…Obesity may be characterized by abnormal sex steroid secretion and reduced sex hormone binding globulin (SHBG) which in turn is related to fat distribution and…”
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Genetic contribution of polymorphism of the GLUT1 and GLUT4 genes to the susceptibility to type 2 (non-insulin-dependent) diabetes mellitus in different populations by PONTIROLI, A. E, CAPRA, F, KOPELMAN, P. G, MOHAN, V, VISWANATHAN, M, VEGLIA, F, FERRARI, M, XIANG, K. S, BELL, G. I, BARONI, M. G, GALTON, D. J, WEAVER, J. U, HITMAN, G. A

“…Polymorphic variation of genes encoding the glucose transporters glycoproteins (GLUT) may contribute to the genetic susceptibility to type 2…”
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Applicability of estimated glomerular filtration rate in stratifying chronic kidney disease by Khatami, Z., Handley, G., Narayanan, K., Weaver, J. U.

“…Objective. The aim of this audit was to evaluate the degree of glomerular filtration rate (GFR) among inpatients and outpatients in a District General…”
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The N363S polymorphism of the glucocorticoid receptor : Potential contribution to central obesity in men and lack of association with other risk factors for coronary heart disease and diabetes mellitus by DOBSON, Mark G, REDFERN, Christopher P. F, UNWIN, Nigel, WEAVER, Jolanta U

“…Considerable evidence suggests that diabetes mellitus and hypertension are influenced by genetic factors. Studies in humans have associated glucocorticoid…”
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An association between hypothalamic-pituitary dysfunction and peripheral endocrine function in extreme obesity by Weaver, J U, Noonan, K, Kopelman, P G

“…The aim was to investigate a possible relationship between measures of insulin secretion and glucose disposal and hypothalamic-pituitary function in extreme…”
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The effect of growth hormone replacement therapy on cortisol-cortisone interconversion in hypopituitary adults: evidence for growth hormone modulation of extrarenal 11β-hydroxysteroid dehydrogenase activity by Gelding, S. V., Taylor, N. F., Wood, P. J., Noonan, K., Weaver, J. U., Wood, D. F., Monson, J. P.

“…OBJECTIVE Growth hormone (GH) replacement therapy in hypopituitary adults has been associated with a decreased urinary ratio of 11‐hydroxy/11‐oxo‐cortisol…”
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Impaired prolactin secretion and body fat distribution in obesity by Weaver, J U, Noonan, K, Kopelman, P G, Coste, M

“…Human obesity shows clustering within families. The hypothesis for the presence of a major gene or genes acting in human obesity is supported by recent…”
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Subclinical hypothyroidism and cardiovascular risk by Razvi, S, Weaver, J U

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