Search Results - "Weatherbee, James A"
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The role of shared receptor motifs and common stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15
Published in Immunity (Cambridge, Mass.) (01-04-1995)“…To understand the molecular bases for cytokine redundancy and plelotropy, we have compared the Stat proteins activated in peripheral blood lymphocytes (PBLs)…”
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Transforming Growth Factor β1: Three-Dimensional Structure in Solution and Comparison with the X-ray Structure of Transforming Growth Factor β2
Published in Biochemistry (Easton) (02-07-1996)“…The three-dimensional solution structure of human transforming growth factor β1 (TGF-β1) has been determined using multinuclear magnetic resonance spectroscopy…”
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Transforming growth factor .beta.1: Secondary structure as determined by heteronuclear magnetic resonance spectroscopy
Published in Biochemistry (Easton) (01-02-1993)Get full text
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Purification and reconstitution of HeLa cell microtubules
Published in Biochemistry (Easton) (19-08-1980)“…Microtubules from suspension cultures of HeLa cells have been purified by carrying them through four complete cycles of polymerization at 37 degrees C and…”
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Characterization of recombinant soluble human transforming growth factor-β receptor Type II (rhTGF-βsRII)
Published in Cytokine (Philadelphia, Pa.) (01-07-1995)“…Recombinant human transforming growth factor soluble receptor Type II (rhTGF-βsRII) corresponding to the 159 amino acid extracellular domain of hTGF-βRII has…”
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Heterodimers of Placenta Growth Factor/Vascular Endothelial Growth Factor
Published in The Journal of biological chemistry (09-02-1996)“…Here we show that the Escherichia coli expressed monomers of placenta growth factor (PLGF)129 and vascular endothelial growth factor (VEGF)165 can be re-folded…”
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A microtubule-associated protein in the mitotic spindle and the interphase nucleus
Published in Nature (London) (21-01-1982)Get full text
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Heterodimers of placenta growth factor/vascular endothelial growth factor. Endothelial activity, tumor cell expression, and high affinity binding to Flk-1/KDR
Published in The Journal of biological chemistry (09-02-1996)“…Here we show that the Escherichia coli expressed monomers of placenta growth factor (PLGF)129 and vascular endothelial growth factor (VEGF)165 can be re-folded…”
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gro-beta, a -C-X-C- chemokine, is an angiogenesis inhibitor that suppresses the growth of Lewis lung carcinoma in mice
Published in The Journal of experimental medicine (01-12-1995)“…We have found that two chemokines, recombinant gro-alpha and gro-beta, specifically inhibit growth factor-stimulated proliferation of capillary endothelial…”
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High-Resolution Solution Structure of the β Chemokine hMIP-1β by Multidimensional NMR
Published in Science (American Association for the Advancement of Science) (25-03-1994)“…The three-dimensional structure of a member of the β subfamily of chemokines, human macrophage inflammatory protein-1β (hMIP-1β), has been determined with the…”
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The Recombinant Proregion of Transforming Growth Factor β 1 (Latency-Associated Peptide) Inhibits Active Transforming Growth Factor β 1 in Transgenic Mice
Published in Proceedings of the National Academy of Sciences - PNAS (11-06-1996)“…All three isoforms of transforming growth factors β (TGF-β 1, TGF-β 2, and TGF-β 3) are secreted as latent complexes and activated extracellularly, leading to…”
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The transforming growth factor-beta system, a complex pattern of cross-reactive ligands and receptors
Published in Cell (13-02-1987)“…A new homodimer form of transforming growth factor-beta (TGF-beta), TGF-beta 2, has been identified in porcine blood platelets. TGF-beta 2 is homologous to…”
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Binding Affinity of Transforming Growth Factor-β for Its Type II Receptor Is Determined by the C-terminal Region of the Molecule
Published in The Journal of biological chemistry (29-11-1996)“…Transforming growth factor-β (TGF-β) isoforms have differential binding affinities for the TGF-β type II receptor (TβRII). In most cells, TGF-β1 and TGF-β3…”
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Circadian characteristics of circulating interleukin-6 in men
Published in Journal of allergy and clinical immunology (01-05-1995)“…Background: The cytokine interleukin-6 (IL-6) is a multifunctional small-peptide molecule that is produced by various types of lymphoid and nonlymphoid cells…”
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Transforming growth factor β1 : secondary structure as determined by heteronuclear magnetic resonance spectroscopy
Published in Biochemistry (Easton) (1993)Get full text
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Aggregation of the chemokine MIP-1 alpha is a dynamic and reversible phenomenon. Biochemical and biological analyses
Published in The Journal of biological chemistry (18-02-1994)“…Macrophage inhibitory protein (MIP)-1 alpha is a potent inhibitor of hemopoietic stem cell proliferation and is a member of a family of pro-inflammatory…”
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Binding Affinity of Transforming Growth Factor-β for Its Type II Receptor Is Determined by the C-terminal Region of the Molecule
Published in The Journal of biological chemistry (29-11-1996)“…Transforming growth factor-β (TGF-β) isoforms have differential binding affinities for the TGF-β type II receptor (TβRII). In most cells, TGF-β1 and…”
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Cell Locomotion in Vitro: Techniques and Observations . C. A. Middleton , J. A. Sharp
Published in The Quarterly review of biology (01-06-1985)Get full text
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Identification and Functional Analysis of Beta-Tubulin Genes by Site Specific Integrative Transformation in Aspergillus nidulans
Published in The Journal of cell biology (01-09-1985)“…We have cloned two different beta-tubulin sequences from the filamentous fungus Aspergillus nidulans. Each was used in the construction of transforming…”
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