Search Results - "Wear, Douglas J"
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Production and characterization of chimeric monoclonal antibodies against Burkholderia pseudomallei and B. mallei using the DHFR expression system
Published in PloS one (09-05-2011)“…Burkholderia pseudomallei (BP) and B. mallei (BM) are closely related gram-negative, facultative anaerobic bacteria which cause life-threatening melioidosis in…”
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Medulloblastoma and Brucellosis - Molecular Evidence of Brucella sp in Association with Central Nervous System Cancer
Published in Journal of Cancer (01-01-2011)“…Neurobrucellosis has been reported to cause lesions in a number of different locations in the central nervous system. Histologically or radiologically, these…”
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Sequential real-time PCR assays applied to identification of genomic signatures in formalin-fixed paraffin-embedded tissues: a case report about brucella-induced osteomyelitis
Published in Military medicine (01-01-2013)“…Brucellosis is a zoonotic infection transmitted from animals to human by ingestion of infected food products, direct contact with an infected animal, or…”
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Development of hydrolysis probe-based real-time PCR for identification of virulent gene targets of Burkholderia pseudomallei and B. mallei--a retrospective study on archival cases of service members with melioidosis and glanders
Published in Military medicine (01-02-2012)“…Burkholderia pseudomallei and B. mallei are two highly pathogenic bacteria responsible for melioidosis and glanders, respectively. Our laboratory developed…”
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Improvement of anti- Burkholderia mouse monoclonal antibody from various phage-displayed single-chain antibody libraries
Published in Journal of immunological methods (30-09-2011)“…To improve anti- Burkholderia monoclonal antibody (MAb) binding affinity, six single chain variable fragments (scFvs) constructed previously were used as…”
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Construction and molecular characterization of mouse single-chain variable fragment antibodies against Burkholderia mallei and Burkholderia pseudomallei
Published in Journal of immunological methods (28-02-2011)“…We have selected two lipopolysaccharide (LPS) specific Burkholderia mallei mouse monoclonal antibodies (mAbs) and four anti-capsular B. pseudomallei-specific…”
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Cat scratch disease: a bacterial infection
Published in Science (American Association for the Advancement of Science) (30-09-1983)“…Histopathologic examination of lymph nodes from 39 patients with clinical and pathological criteria for cat scratch disease revealed delicate pleomorphic…”
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Mycoplasmas and Oncogenesis: Persistent Infection and Multistage Malignant Transformation
Published in Proceedings of the National Academy of Sciences - PNAS (24-10-1995)“…Oncogenic potential of human mycoplasmas was studied using cultured mouse embryo cells, C3H/10T1/2 (C3H). Mycoplasma fermentans and Mycoplasma penetrans,…”
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Cat-Scratch Disease: Isolation and Culture of the Bacterial Agent
Published in JAMA : the journal of the American Medical Association (04-03-1988)“…A gram-negative bacterium or its cell wall—defective variants were isolated from lymph nodes of ten patients with cat-scratch disease. Cultured bacteria were…”
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Mycoplasma hominis Lipid-Associated Membrane Protein Antigens for Effective Detection of M. hominis-Specific Antibodies in Humans
Published in Clinical infectious diseases (15-05-2003)“…Lipid-associated membrane proteins (LAMPs) from 14 Mycoplasma hominis isolates or strains share similar protein and antigenicity profiles. Of 31 human…”
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Enhancement of HIV-1 Cytocidal Effects in CD4$^+$ Lymphocytes by the AIDS-Associated Mycoplasma
Published in Science (American Association for the Advancement of Science) (01-03-1991)“…Coinfection with Mycoplasma fermentans (incognitus strain) enhances the ability of human immunodeficiency virus type-1 (HIV-1) to induce cytopathic effects on…”
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Mycoplasmal infections alter gene expression in cultured human prostatic and cervical epithelial cells
Published in FEMS immunology and medical microbiology (01-01-2000)“…Abstract To better understand how infections by mycoplasmas affect gene expression in human cells, we quantitatively measured the transcripts of 38 cytokine…”
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Demonstration of de novo HIV type 1 production by detection of multiply spliced and unspliced HIV type 1 RNA in paraffin-embedded tonsils
Published in AIDS research and human retroviruses (20-07-2002)“…HIV-1 infection of tonsils takes place when virus spreads systemically, and may occur when tonsillar tissue serves as the initial portal of HIV-1 entry. The…”
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Case 22-1992: Pathogenesis of Cat Scratch Disease
Published in The New England journal of medicine (26-11-1992)“…To the Editor: Case Record 22–1992 (May 28 issue) 1 described a 6 1/2-year-old girl with a diagnosis of cat scratch disease. The addendum noted that Afipia…”
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Mycoplasma penetrans infections and seroconversion in patients with AIDS: identification of major mycoplasmal antigens targeted by host antibody response
Published in FEMS immunology and medical microbiology (01-06-2005)“…We examined Mycoplasma penetrans-specific antibodies in sera of five male homosexual AIDS patients from whom M. penetrans was isolated during the disease…”
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Identification of Mycoplasma incognitus infection in patients with AIDS: an immunohistochemical, in situ hybridization and ultrastructural study
Published in The American journal of tropical medicine and hygiene (01-11-1989)“…Monoclonal antibodies (Mabs) were developed against antigens from a pure culture of Mycoplasma incognitus grown in modified SP-4 medium. All the Mabs obtained…”
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Virus-like infectious agent (VLIA) is a novel pathogenic mycoplasma: Mycoplasma incognitus
Published in The American journal of tropical medicine and hygiene (01-11-1989)“…The newly recognized pathogenic virus-like infectious agent (VLIA), originally reported in patients with AIDS but also known to be pathogenic in previously…”
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Encephalitis in Newborn Hamsters after Intracerebral Injection of Attenuated Human Measles Virus
Published in Nature (London) (26-09-1970)Get full text
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Association of the virus-like infectious agent originally reported in patients with AIDS with acute fatal disease in previously healthy non-AIDS patients
Published in The American journal of tropical medicine and hygiene (01-09-1989)“…We studied 6 patients from 6 different geographic areas who presented with acute flu-like illnesses. The patients developed persistent fevers, lymphadenopathy…”
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Smallpox: The Greatest Killer: Smallpox in History
Published in JAMA : the journal of the American Medical Association (05-03-2003)Get full text
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