Search Results - "Wazir, Junaid"
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Reinvigorating exhausted CD8+ cytotoxic T lymphocytes in the tumor microenvironment and current strategies in cancer immunotherapy
Published in Medicinal research reviews (01-01-2021)“…Immunotherapy has revolutionized the treatment of cancer in recent years and achieved overall success and long‐term clinical benefit in patients with a wide…”
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2
Comparative transcriptomic analysis of THP‐1‐derived macrophages infected with Mycobacterium tuberculosis H37Rv, H37Ra and BCG
Published in Journal of cellular and molecular medicine (01-11-2021)“…Tuberculosis (TB) remains a worldwide healthcare concern, and the exploration of the host‐pathogen interaction is essential to develop therapeutic modalities…”
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3
Phytotherapy and physical therapy in the management of chronic prostatitis–chronic pelvic pain syndrome
Published in International urology and nephrology (01-07-2019)“…Chronic prostatitis (CP)/chronic pelvic pain syndrome (CPPS) is one of the four category prostatitis, and the prevalence is over 90–95% in prostatitis. Because…”
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4
Respiratory exposure to PM2.5 soluble extract induced chronic lung injury by disturbing the phagocytosis function of macrophage
Published in Environmental science and pollution research international (01-02-2022)“…Exposure to airborne urban particles is a contributing factor for the development of multiple types of respiratory diseases; its pathological role as a cause…”
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5
An integrative transcriptome study reveals Ddit4/Redd1 as a key regulator of cancer cachexia in rodent models
Published in Cell death & disease (26-06-2021)“…Cancer cachexia is a multifactorial metabolic syndrome that causes up to 20% of cancer-related deaths. Muscle atrophy, the hallmark of cancer cachexia,…”
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6
Chronic prostatitis/chronic pelvic pain syndrome and prostate cancer: study of immune cells and cytokines
Published in Fundamental & clinical pharmacology (01-04-2020)“…Prostate cancer and prostatitis are both significant health concerns. A large number of studies have established that the occurrence of the two is closely…”
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Protective effect of α7 nicotinic acetylcholine receptor activation on experimental colitis and its mechanism
Published in Molecular medicine (Cambridge, Mass.) (04-09-2022)“…Abstract Background Inflammatory bowel disease (IBD) is a common chronic remitting disease with no satisfactory treatment. The aim of this study was to…”
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8
A comprehensive review of animal models for cancer cachexia: Implications for translational research
Published in Genes & diseases (01-11-2024)“…Cancer cachexia is a multifactorial syndrome characterized by progressive weight loss and a disease process that nutritional support cannot reverse. Although…”
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Experimental autoimmune prostatitis: different antigens induction and antigen-specific therapy
Published in International urology and nephrology (01-04-2021)“…Purpose Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) has uncertain etiology and lacks effective treatment. Autoimmunity is an important…”
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10
Targeting HSP90 Inhibits Proliferation and Induces Apoptosis Through AKT1/ERK Pathway in Lung Cancer
Published in Frontiers in pharmacology (14-01-2022)“…Lung cancer is one of the most common malignant cancers worldwide. Searching for specific cancer targets and developing efficient therapies with lower toxicity…”
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11
The effectiveness of Hedyotis diffusa Willd extract in a mouse model of experimental autoimmune prostatitis
Published in Andrologia (01-02-2021)“…Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a frustrating and often debilitating disease. Current studies have shown that Traditional Chinese…”
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12
Sulforaphane alleviates psoriasis by enhancing antioxidant defense through KEAP1-NRF2 Pathway activation and attenuating inflammatory signaling
Published in Cell death & disease (25-11-2023)“…Psoriasis is a chronic inflammatory skin disease that affects millions of people worldwide. Sulforaphane (SFN) has been shown to have anti-inflammatory and…”
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Therapeutic effects of Qianlie Tongli decoction on chronic prostatitis/chronic pelvic pain syndrome induced by peptide T2 in mice
Published in Journal of pharmacy and pharmacology (01-10-2020)“…Objectives This study was undertaken to reveal therapeutic effects and the preliminary mechanism of Chinese medicine formula Qianlie Tongli decoction (QTD) in…”
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14
Efficacy of acupuncture in the treatment of chronic prostatitis-chronic pelvic pain syndrome: a review of the literature
Published in International urology and nephrology (01-12-2019)“…Among one of the four category prostatitis, chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is the disease with unknown etiology and having 90–95%…”
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15
Herbal nutraceutical treatment of chronic prostatitis–chronic pelvic pain syndrome: a literature review
Published in International urology and nephrology (01-08-2021)“…Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is the most frequent form of prostatitis, and has a serious impact on patients’ quality of life, and…”
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16
Alpha-7 nicotinic acetylcholine receptor agonist alleviates psoriasis-like inflammation through inhibition of the STAT3 and NF-κB signaling pathway
Published in Cell death discovery (30-03-2022)“…Psoriasis is a chronic inflammatory cutaneous disease; it has been discovered that stimulation of the nervous system increases susceptibility to psoriasis…”
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Effect of Oral T2 Antigen on Chronic Prostatitis/Chronic Pelvic Pain Syndrome in Mice Model
Published in Inflammation (01-12-2019)“…The exact etiology and pathogenesis of chronic prostatitis (CP/CPPS) remain unclear. However, autoimmunity is a widely known theory. Precise treatment of…”
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18
Creatine modulates cellular energy metabolism and protects against cancer cachexia-associated muscle wasting
Published in Frontiers in pharmacology (07-12-2022)“…Cancer cachexia is a multifactorial syndrome defined by progressive loss of body weight with specific depletion of skeletal muscle and adipose tissue. Since…”
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2-Deoxy-D-glucose Alleviates Cancer Cachexia-Induced Muscle Wasting by Enhancing Ketone Metabolism and Inhibiting the Cori Cycle
Published in Cells (Basel, Switzerland) (25-09-2022)“…Cachexia is characterized by progressive weight loss accompanied by the loss of specific skeletal muscle and adipose tissue. Increased lactate production,…”
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Long-term exposure to PM2.5 aggravates pulmonary fibrosis and acute lung injury by disrupting Nrf2-mediated antioxidant function
Published in Environmental pollution (1987) (15-11-2022)“…Epidemiological studies have indicated that exposure to ambient air-borne fine particulate matter (PM2.5) is associated with many cardiopulmonary diseases;…”
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