Search Results - "Way, Kerrie J."
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Identification of PKC-isoform-specific biological actions using pharmacological approaches
Published in Trends in Pharmacological Sciences (01-05-2000)“…The protein kinase C (PKC) family consists of at least 12 isoforms that possess distinct differences in structure, substrate requirement, expression and…”
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Activation of Vascular Protein Kinase C-β Inhibits Akt-Dependent Endothelial Nitric Oxide Synthase Function in Obesity-Associated Insulin Resistance
Published in Diabetes (New York, N.Y.) (01-03-2006)“…Activation of Vascular Protein Kinase C-β Inhibits Akt-Dependent Endothelial Nitric Oxide Synthase Function in Obesity-Associated Insulin Resistance Keiko…”
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Expression of Connective Tissue Growth Factor Is Increased in Injured Myocardium Associated With Protein Kinase C β2 Activation and Diabetes
Published in Diabetes (New York, N.Y.) (01-09-2002)“…Expression of Connective Tissue Growth Factor Is Increased in Injured Myocardium Associated With Protein Kinase C β2 Activation and Diabetes Kerrie J. Way 1 ,…”
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The generation and properties of human macrophage populations from hemopoietic stem cells
Published in Journal of leukocyte biology (01-05-2009)“…Information about the development and function of human macrophage lineage populations, such as osteoclasts, is limited because of the lack of defined in vitro…”
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Regulation of Vascular Endothelial Growth Factor Expression and Vascularization in the Myocardium by Insulin Receptor and PI3K/Akt Pathways in Insulin Resistance and Ischemia
Published in Arteriosclerosis, thrombosis, and vascular biology (01-04-2006)“…OBJECTIVE—This study characterized the role of insulin receptors and resistance on vascular endothelial growth factor (VEGF) expression and myocardial…”
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Differential Regulation of Angiotensin II-induced Expression of Connective Tissue Growth Factor by Protein Kinase C Isoforms in the Myocardium
Published in The Journal of biological chemistry (22-04-2005)“…Protein kinase C (PKC) and angiotensin II (AngII) can regulate cardiac function in pathological conditions such as in diabetes or ischemic heart disease. We…”
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The effect of tissue type-plasminogen activator deletion and associated fibrin(ogen) deposition on macrophage localization in peritoneal inflammation
Published in Thrombosis and haemostasis (01-04-2006)“…There are two plasminogen activators (PAs), urokinase type-PA (u-PA) and tissue type-PA (t-PA). While u-PA is considered to be involved in cellular migration…”
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Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic states: A possible explanation for impaired collateral formation in cardiac tissue
Published in Circulation (New York, N.Y.) (22-01-2002)“…Inadequate angiogenic response to ischemia in the myocardium of diabetic patients could result in poor collateral formation. Yet, excessive neovascularization…”
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Urokinase-type plasminogen activator and arthritis progression: role in systemic disease with immune complex involvement
Published in Arthritis research & therapy (01-01-2010)“…Urokinase-type plasminogen activator (u-PA) has been implicated in fibrinolysis, cell migration, latent cytokine activation, cell activation, T-cell…”
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Applications of inhibitors for protein kinase C and their isoforms
Published in Methods in molecular biology (Clifton, N.J.) (2003)Get more information
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The effects of diabetes on nitric oxide-mediated responses in rat corpus cavernosum
Published in European journal of pharmacology (02-07-1999)“…Nitric oxide (NO)-mediated responses were investigated in corpora cavernosa isolated from 8-week diabetic rats. Relaxations to field stimulation were abolished…”
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Insulin reversal of impaired nitrergic transmission in the anococcygeus muscle from diabetic rats
Published in Pharmacology (01-09-1999)“…The aim of this study was to investigate whether insulin could reverse the impairment in nitrergic neurotransmission in the anococcygeus muscle from…”
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The aldose reductase inhibitor sorbinil does not prevent the impairment in nitric oxide-mediated neurotransmission in anococcygeus muscle from diabetic rats
Published in European journal of pharmacology (27-12-1996)“…This study investigated whether increased polyol pathway activity could contribute to alterations in nitrergic neurotransmission in anococcygeus muscles from…”
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Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic states: A possible explanation for impaired
Published in Circulation (New York, N.Y.) (22-01-2002)“…BACKGROUND: Inadequate angiogenic response to ischemia in the myocardium of diabetic patients could result in poor collateral formation. Yet, excessive…”
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15
Activation of vascular protein kinase C-[beta] inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance
Published in Diabetes (New York, N.Y.) (01-03-2006)“…Activation of protein kinase C (PKC) in vascular tissue is associated with endothelial dysfunction and insulin resistance. However, the effect of vascular PKC…”
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Expression of connective tissue growth factor is increased in injured myocardium associated with protein kinase C beta2 activation and diabetes
Published in Diabetes (New York, N.Y.) (01-09-2002)“…Protein kinase C (PKC) beta isoform activity is increased in myocardium of diabetic rodents and heart failure patients. Transgenic mice overexpressing PKCbeta2…”
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Effect of diabetes and elevated glucose on nitric oxide‐mediated neurotransmission in rat anococcygeus muscle
Published in British journal of pharmacology (01-06-1995)“…1 Nitric oxide (NO)‐mediated neurotransmission is impaired in anococcygeus muscle from 8‐week streptozotocin‐induced diabetic rats. This study investigated the…”
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Diabetes does not alter the activity and localisation of nitric oxide synthase in the rat anococcygeus muscle
Published in Journal of the autonomic nervous system (16-04-1999)“…Functional studies have revealed diabetes specifically impairs smooth muscle reactivity to nitric oxide in the rat anococcygeus muscle. The present study was…”
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