Search Results - "Wawrzynski, James"

Systemic gene therapy rescues retinal dysfunction and hearing loss in a model of Norrie disease by Pauzuolyte, Valda, Patel, Aara, Wawrzynski, James R, Ingham, Neil J, Leong, Yeh Chwan, Karda, Rajvinder, Bitner‐Glindzicz, Maria, Berger, Wolfgang, Waddington, Simon N, Steel, Karen P, Sowden, Jane C

“…Abstract Deafness affects 5% of the world's population, yet there is a lack of treatments to prevent hearing loss due to genetic causes. Norrie disease is a…”
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Feasibility of Human Factors Immersive Simulation Training in Ophthalmology: The London Pilot by Saleh, George M, Wawrzynski, James R, Saha, Kamran, Smith, Phillip, Flanagan, Declan, Hingorani, Melanie, John, Clinton, Sullivan, Paul

“…Human factors training can enhance teamworking and reduce error. It is used regularly in certain medical disciplines, but its use has not been established for…”
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Spectrum of Mutations in NDP Resulting in Ocular Disease; a Systematic Review by Wawrzynski, James, Patel, Aara, Badran, Abdul, Dowell, Isaac, Henderson, Robert, Sowden, Jane C

“…The inner retina is supplied by three intraretinal capillary plexi whereas the outer retina is supplied by the choroidal circulation: NDP is essential for…”
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Evolution and Applications of Artificial Intelligence to Cataract Surgery by Lindegger, Daniel Josef, Wawrzynski, James, Saleh, George Michael

“…Despite significant recent advances in artificial intelligence (AI) technology within several ophthalmic subspecialties, AI seems to be underutilized in the…”
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Optical Coherence Tomography Imaging of the Proximal Lacrimal System by Wawrzynski, James R., Smith, Julie, Sharma, Anant, Saleh, George M.

“…Abstract Introduction: There are currently no routinely used imaging modalities for the proximal lacrimal system. Optical Coherence Tomography (OCT) is a safe…”
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Antagonism at NMDA receptors, but not β-adrenergic receptors, disrupts the reconsolidation of pavlovian conditioned approach and instrumental transfer for ethanol-associated conditioned stimuli by Milton, Amy L., Schramm, Moritz J. W., Wawrzynski, James R., Gore, Felicity, Oikonomou-Mpegeti, Faye, Wang, Nancy Q., Samuel, Daniel, Economidou, Daina, Everitt, Barry J.

“…Rationale Reconsolidation is the process by which memories require restabilisation following destabilisation at retrieval. Since even old, well-established…”
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Reply: Comments on surgical iridotomy technique by Sharma, Anant, FRCOphth, Wawrzynski, James, MB, BChir

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Shunt Testing In Vivo: Observational Study of Problems with Ventricular Catheter by Czosnyka, Zofia H, Sinha, Rohitiwa, Morgan, James A D, Wawrzynski, James R, Price, Steven J, Garnett, Matthew, Pickard, John D, Czosnyka, M

“…Most shunt obstructions happen at the inlet of the ventricular catheter. Three hundred six infusion studies from 2007 to 2011 were classified as having a…”
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An Automated Detection System for Microaneurysms That Is Effective across Different Racial Groups by Tang, Hongying, Smith, Phillip, Hu, Yin, Wang, Su, Al Turk, Lutfiah Ismail, Peto, Tunde, Caputo, Silvestro, Wawrzynski, James, Saleh, George M., Da Cruz, Lyndon

“…Patients without diabetic retinopathy (DR) represent a large proportion of the caseload seen by the DR screening service so reliable recognition of the absence…”
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Man versus Machine: Software Training for Surgeons- An Objective Evaluation of Human and Computer-Based Training Tools for Cataract Surgical Performance by Saleh, George M., Caputo, Silvestro, Tang, Hongying, Wawrzynski, James, Jones, Simon, Sharma, Anant, Emeriewen, Krisztina, Smith, Phillip, Din, Nizar, Sullivan, Paul

“…This study aimed to address two queries: firstly, the relationship between two cataract surgical feedback tools for training, one human and one software based,…”
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Intravitreal enzyme replacement for inherited retinal diseases by Rodriguez-Martinez, Ana Catalina, Wawrzynski, James, Henderson, Robert H

“…This paper provides an update on intravitreal (IVT) enzyme replacement therapy (ERT) in metabolic retinal diseases; particularly neuronal ceroid lipofuscinosis…”
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Acute Angle Closure in Knobloch Syndrome by Wawrzynski, James, Than, Jonathan, Gillam, Matthew, Foster, Paul J.

“…We report cases of acute angle closure in two young highly myopic siblings with Knobloch syndrome. To our knowledge, this is the first report of acute angle…”
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Acute Angle Closure in Knobloch Syndrome by Wawrzynski, James, Than, Jonathan, Gillam, Matthew, Foster, Paul J.

“…We report cases of acute angle closure in 2 young highly myopic siblings with Knobloch syndrome. To our knowledge, this is the first report of acute angle…”
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First in man study of intravitreal tripeptidyl peptidase 1 for CLN2 retinopathy by Wawrzynski, James, Martinez, Ana Rodriguez, Thompson, Dorothy Ann, Ram, Dipak, Bowman, Richard, Whiteley, Rebecca, Gan, Chin, Harding, Louise, Mortensen, Amanda, Mills, Philippa, Gissen, Paul, Henderson, Robert H.

“…Background/Objectives CLN2 Batten Disease is a fatal neurodegenerative condition of childhood associated with retinal dystrophy and blindness…”
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Reply by Sharma, Anant, Wawrzynski, James, Bishop, David S.

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Automated feature-based grading and progression analysis of diabetic retinopathy by Al-Turk, Lutfiah, Wawrzynski, James, Wang, Su, Krause, Paul, Saleh, George M., Alsawadi, Hend, Alshamrani, Abdulrahman Zaid, Peto, Tunde, Bastawrous, Andrew, Li, Jingren, Tang, Hongying Lilian

“…Background In diabetic retinopathy (DR) screening programmes feature-based grading guidelines are used by human graders. However, recent deep learning…”
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Novel non-sense mutation in RP2 (c.843_844insT/p.Arg282fs) is associated with a severe phenotype of retinitis pigmentosa without evidence of primary retinal pigment epithelium involvement by Horner, Faye, Wawrzynski, James, MacLaren, Robert E

“…Retinitis pigmentosa (RP) relates to a heterogeneous group of rod-cone dystrophies of varying genetic aetiology. There is currently great interest in gene…”
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Evidence Based Prediction and Progression Monitoring on Retinal Images from Three Nations by Al Turk, Lutfiah, Wang, Su, Krause, Paul, Wawrzynski, James, Saleh, George M, Alsawadi, Hend, Alshamrani, Abdulrahman Zaid, Peto, Tunde, Bastawrous, Andrew, Li, Jingren, Tang, Hongying Lilian

“…The aim of this work is to demonstrate how a retinal image analysis system, DAPHNE, supports the optimization of diabetic retinopathy (DR) screening programs…”
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Scaling the punctum and canaliculus in patients undergoing punctoplasty surgery: A prospective cohort study by Nesaratnam, Nisha, Emeriewen, Krisztina, Smith, Julie, David, Beena, Wawrzynski, James, Sharma, Anant, Saleh, George M

“…Optical Coherence Tomography (OCT) is a safe and non-invasive method of high-resolution cross-sectional imaging of tissue microstructures using infrared…”
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Reply by Sharma, Anant, FRCOphth, Wawrzynski, James, MB, BChir, Bishop, David S., BA

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