Search Results - "Waubant, E."

Gut microbiota in early pediatric multiple sclerosis: a case−control study by Tremlett, H., Fadrosh, D. W., Faruqi, A. A., Zhu, F., Hart, J., Roalstad, S., Graves, J., Lynch, S., Waubant, E.

“…Background and purpose Alterations in the gut microbial community composition may be influential in neurological disease. Microbial community profiles were…”
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Fatigue and depression predict quality of life in patients with early multiple sclerosis: a longitudinal study by Nourbakhsh, B., Julian, L., Waubant, E.

“…Background and purpose The clinical predictors of health‐related quality of life (HRQoL) in multiple sclerosis (MS) have mainly been studied in patients with…”
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Systematic review of disease-modifying therapies to assess unmet needs in multiple sclerosis: tolerability and adherence by Giovannoni, G, Southam, E, Waubant, E

“…Reviews of therapeutic drugs usually focus on the highly selected and closely monitored patient populations from randomized controlled trials. The objective of…”
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Asymptomatic spinal cord lesions predict disease progression in radiologically isolated syndrome by OKUDA, D. T, MOWRY, E. M, CREE, B. A. C, CRABTREE, E. C, GOODIN, D. S, WAUBANT, E, PELLETIER, D

“…Technological advancements in neuroimaging and the increased use of these diagnostic modalities are responsible for the discovery of incidentally identified…”
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An open label study of the effects of rituximab in neuromyelitis optica by CREE, B. A. C, LAMB, S, MORGAN, K, CHEN, A, WAUBANT, E, GENAIN, C

“…Eight patients with worsening neuromyelitis optica were treated with rituximab to achieve B cell depletion. Treatment was well tolerated. Six of eight patients…”
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Incidence of acquired CNS demyelinating syndromes in a multiethnic cohort of children by LANGER-GOULD, A, ZHANG, J. L, CHUNG, J, YEUNG, Y, WAUBANT, E, YAO, J

“…To determine whether the incidence and clinical features of pediatric multiple sclerosis (MS) and other forms of pediatric acquired demyelinating syndromes…”
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Incidental MRI anomalies suggestive of multiple sclerosis : The radiologically isolated syndrome by OKUDA, D. T, MOWRY, E. M, BEHESHTIAN, A, WAUBANT, E, BARANZINI, S. E, GOODIN, D. S, HAUSER, S. L, PELLETIER, D

“…The discovery and broad application of MRI in medicine has led to an increased awareness in the number of patients with incidental white matter pathology in…”
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A consensus protocol for the standardization of cerebrospinal fluid collection and biobanking by TEUNISSEN, C. E, PETZOLD, A, HINTZEN, R. Q, HUGHES, S. G, JOHNSON, M. H, KRASULOVA, E, KUHLE, J, MAGNONE, M. C, RAJDA, C, REJDAK, K, SCHMIDT, H. K, VAN PESCH, V, BENNETT, J. L, WAUBANT, E, WOLF, C, GIOVANNONI, G, HEMMER, B, TUMANI, H, DEISENHAMMER, F, BERVEN, F. S, BRUNDIN, L, COMABELLA, M, FRANCIOTTA, D, FREDERIKSEN, J. L, FLEMING, J. O, FURLAN, R

“…There is a long history of research into body fluid biomarkers in neurodegenerative and neuroinflammatory diseases. However, only a few biomarkers in CSF are…”
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Modafinil for fatigue in MS : A randomized placebo-controlled double-blind study by STANKOFF, B, WAUBANT, E, CONFAVREUX, C, EDAN, G, DEBOUVERIE, M, RUMBACH, L, MOREAU, T, PELLETIER, J, LUBETZKI, C, CLANET, M

“…To assess whether modafinil, a wakefulness-promoting agent, is useful for fatigue in patients with multiple sclerosis (MS). Patients with MS with stable…”
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Switching first-line disease-modifying therapy after failure: impact on the course of relapsing–remitting multiple sclerosis by Gajofatto, A, Bacchetti, P, Grimes, B, High, A, Waubant, E

“…Background Options for non-responders to relapsing–remitting multiple sclerosis (RRMS) first-line disease-modifying therapies (DMT) are limited. We explored…”
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Central vein sign: A diagnostic biomarker in multiple sclerosis (CAVS-MS) study protocol for a prospective multicenter trial by Ontaneda, D., Sati, P., Raza, P., Kilbane, M., Gombos, E., Alvarez, E., Azevedo, C., Calabresi, P., Cohen, J.A., Freeman, L., Henry, R.G., Longbrake, E.E., Mitra, N., Illenberger, N., Schindler, M., Moreno-Dominguez, D., Ramos, M., Mowry, E., Oh, J., Rodrigues, P., Chahin, S., Kaisey, M., Waubant, E., Cutter, G., Shinohara, R., Reich, D.S., Solomon, A., Sicotte, N.L.

“…•Approximately one in five patients with MS do not have the disease.•The central vein differentiates multiple sclerosis from other white matter lesions.•The…”
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Vitamin D in clinically isolated syndrome: evidence for possible neuroprotection by Mowry, E. M., Pelletier, D., Gao, Z., Howell, M. D., Zamvil, S. S., Waubant, E.

“…Background and purpose Vitamin D status has been associated with inflammatory activity in multiple sclerosis (MS), but it is not known if it is associated with…”
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Common viruses associated with lower pediatric multiple sclerosis risk by WAUBANT, E, MOWRY, E. M, BELMAN, A, MILAZZO, M, GORMAN, M, WEINSTOCK-GUTTMAN, B, RODRIGUEZ, M, OKSENBERG, J. R, JAMES, J. A, KRUPP, L, CHITNIS, T, YEH, E. A, KUNTZ, N, NESS, J, CHABAS, D, STROBER, J, MCDONALD, J

“…Because common viruses are encountered during childhood, pediatric multiple sclerosis (MS) offers a unique opportunity to investigate the influence of these…”
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Neurite Orientation Dispersion and Density Imaging for Assessing Acute Inflammation and Lesion Evolution in MS by Sacco, S, Caverzasi, E, Papinutto, N, Cordano, C, Bischof, A, Gundel, T, Cheng, S, Asteggiano, C, Kirkish, G, Mallott, J, Stern, W A, Bastianello, S, Bove, R M, Gelfand, J M, Goodin, D S, Green, A J, Waubant, E, Wilson, M R, Zamvil, S S, Cree, B A, Hauser, S L, Henry, R G

“…MR imaging is essential for MS diagnosis and management, yet it has limitations in assessing axonal damage and remyelination. Gadolinium-based contrast agents…”
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Longitudinal evaluation of cognitive functioning in pediatric multiple sclerosis: report from the US Pediatric Multiple Sclerosis Network by Charvet, LE, O’Donnell, EH, Belman, AL, Chitnis, T, Ness, JM, Parrish, J, Patterson, M, Rodriguez, M, Waubant, E, Weinstock-Guttman, B, Krupp, LB

“…Background: Approximately one-third of those with pediatric-onset multiple sclerosis (MS) experience cognitive impairment. Less is known concerning their…”
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Younger children with MS have a distinct CSF inflammatory profile at disease onset by CHABAS, D, NESS, J, RODRIGUEZ, M, WEINSTOCK-GUTTMAN, B, KRUPP, L. B, WAUBANT, E, BELMAN, A, YEH, E. A, KUNTZ, N, GORMAN, M. P, STROBER, J. B, DE KOUCHKOVSKY, I, MCCULLOCH, C, CHITNIS, T

“…The clinical and MRI presentation differs between earlier- and later-onset pediatric multiple sclerosis (MS), whereas the effect of age on the CSF inflammatory…”
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NMDA receptor encephalitis mimicking seronegative neuromyelitis optica by Kruer, M C, Koch, T K, Bourdette, D N, Chabas, D, Waubant, E, Mueller, S, Moscarello, M A, Dalmau, J, Woltjer, R L, Adamus, G

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Vanishing MS T2-bright lesions before puberty : A distinct MRI phenotype? by CHABAS, D, CASTILLO-TRIVINO, T, MOWRY, E. M, STROBER, J. B, GLENN, O. A, WAUBANT, E

“…Multiple sclerosis (MS) onset before puberty may have a distinct clinical presentation. Pediatric patients with MS may less often meet MRI diagnostic criteria…”
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Composite end points to assess delay of disability progression by MS treatments by Zhang, J, Waubant, E, Cutter, G, Wolinsky, JS, Leppert, D

“…Background: The Expanded Disability Status Scale (EDSS) has low sensitivity and reliability for detecting sustained disability progression (SDP) in multiple…”
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Genotype-Phenotype Correlations in Multiple Sclerosis: "HLA" Genes Influence Disease Severity Inferred by [superscript 1]HMR Spectroscopy and MRI Measures by Okuda, D. T, Srinivasan, R, Oksenberg, J. R, Goodin, D. S, Baranzini, S. E, Beheshtian, A, Waubant, E, Zamvil, S. S, Leppert, D, Qualley, P, Lincoln, R, Gomez, R, Caillier, S, George, M, Wang, J, Nelson, S. J, Cree, B. A. C, Hauser, S. L, Pelletier, D

“…Genetic susceptibility to multiple sclerosis (MS) is associated with the human leukocyte antigen (HLA) "DRB1*1501" allele. Here we show a clear association…”
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