Search Results - "Wattler, S"

The dominant alopecia phenotypes Bareskin, Rex-denuded, and Reduced Coat 2 are caused by mutations in gasdermin 3 by Runkel, F., Marquardt, A., Stoeger, C., Kochmann, E., Simon, D., Kohnke, B., Korthaus, D., Wattler, F., Fuchs, H., Hrabé de Angelis, M., Stumm, G., Nehls, M., Wattler, S., Franz, T., Augustin, M.

“…Reduced Coat 2 ( Rco2) is an ENU-induced mutation affecting hair follicle morphogenesis by an abnormal and protracted catagen. We describe chromosomal mapping…”
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Efficient and fast targeted production of murine models based on ENU mutagenesis by Augustin, M, Sedlmeier, R, Peters, T, Huffstadt, U, Kochmann, E, Simon, D, Schöniger, M, Garke-Mayerthaler, S, Laufs, J, Mayhaus, M, Franke, S, Klose, M, Graupner, A, Kurzmann, M, Zinser, C, Wolf, A, Voelkel, M, Kellner, M, Kilian, M, Seelig, S, Koppius, A, Teubner, A, Korthaus, D, Nehls, M, Wattler, S

“…Mice with targeted genetic alterations are the most effective tools for deciphering organismal gene function. We generated an ENU-based parallel C3HeB/FeJ…”
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Structural and phylogenetic characterization of human SLURP-1, the first secreted mammalian member of the Ly-6/uPAR protein superfamily by ADERMANN, KNUT, WATTLER, FRANK, WATTLER, SIGRID, HEINE, GABRIELE, MEYER, MARKUS, FORSSMANN, WOLF-GEORG, NEHLS, MICHAEL

“…Members of the Ly-6/uPAR protein family share one or several repeat units of the Ly-6/uPAR domain that is defined by a distinct disulfide bonding pattern…”
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A Combined Analysis of Genomic and Primary Protein Structure Defines the Phylogenetic Relationship of New Members of the T-Box Family by Wattler, Sigrid, Russ, Andreas, Evans, Martin, Nehls, Michael

“…T-box genes form an ancient family of putative transcriptional regulators characterized by a region of homology to the DNA-binding domain of the murine…”
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Synergistic interaction of two independent genetic loci causes extreme elevation of serum IgA in mice by Schneider, B, Hanke, P, Jagla, W, Wattler, S, Nehls, M, Grosse, J, Schröder, A, Laufs, J

“…Understanding the molecular regulation of immunoglobulin A (IgA) expression is important as it plays an essential role in the first-line defence through…”
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Failure to Degrade Poly(ADP-Ribose) Causes Increased Sensitivity to Cytotoxicity and Early Embryonic Lethality by Koh, David W., Lawler, Ann M., Poitras, Marc F., Sasaki, Masayuki, Wattler, Sigrid, Nehls, Michael C., Stöger, Tobias, Poirier, Guy G., Dawson, Valina L., Dawson, Ted M., Snyder, Solomon H.

“…The metabolism of poly(ADP-ribose) (PAR) is critical for genomic stability in multicellular eukaryotes. Here, we show that the failure to degrade PAR by means…”
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Mutations in Dynein Link Motor Neuron Degeneration to Defects in Retrograde Transport by Hafezparast, Majid, Klocke, Rainer, Ruhrberg, Christiana, Marquardt, Andreas, Ahmad-Annuar, Azlina, Bowen, Samantha, Lalli, Giovanna, Witherden, Abi S., Hummerich, Holger, Nicholson, Sharon, Morgan, P. Jeffrey, Oozageer, Ravi, Priestley, John V., Averill, Sharon, King, Von R., Ball, Simon, Peters, Jo, Toda, Takashi, Yamamoto, Ayumu, Hiraoka, Yasushi, Augustin, Martin, Korthaus, Dirk, Wattler, Sigrid, Wabnitz, Philipp, Dickneite, Carmen, Lampel, Stefan, Boehme, Florian, Peraus, Gisela, Popp, Andreas, Rudelius, Martina, Schlegel, Juergen, Fuchs, Helmut, de Angelis, Martin Hrabe, Schiavo, Giampietro, Shima, David T., Russ, Andreas P., Stumm, Gabriele, Martin, Joanne E., Elizabeth M. C. Fisher

“…Degenerative disorders of motor neurons include a range of progressive fatal diseases such as amyotrophic lateral sclerosis (ALS), spinal-bulbar muscular…”
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Diverse Psychotomimetics Act through a Common Signaling Pathway by Svenningsson, Per, Tzavara, Eleni T., Carruthers, Robert, Rachleff, Ilan, Wattler, Sigrid, Nehls, Michael, McKinzie, David L., Fienberg, Allen A., Nomikos, George G., Greengard, Paul

“…Three distinct classes of drugs: dopaminergic agonists (such as D-amphetamine), serotonergic agonists (such as LSD), and glutamatergic antagonists (such as…”
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Eomesodermin is required for mouse trophoblast development and mesoderm formation by Russ, Andreas P, Wattler, Sigrid, Colledge, William H, Aparicio, Samuel A. J. R, Carlton, Mark B. L, Pearce, Jonathan J, Barton, Sheila C, Surani, M. Azim, Ryan, Kenneth, Nehls, Michael C, Wilson, Valerie, Evans, Martin J

“…The earliest cell fate decision in the mammalian embryo separates the extra-embryonic trophoblast lineage, which forms the fetal portion of the placenta, from…”
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Isolation and biochemical characterization of LEAP‐2, a novel blood peptide expressed in the liver by Krause, Alexander, Sillard, Rannar, Kleemeier, Burkhard, Klüver, Enno, Maronde, Erik, Conejo‐García, José Ramon, Forssmann, Wolf Georg, Schulz‐Knappe, Peter, Nehls, Michael C., Wattler, Frank, Wattler, Sigrid, Adermann, Knut

“…The human genome contains numerous genes whose protein products are unknown in terms of structure, interaction partner, expression, and function. To unravel…”
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Mouse β-Defensin 3 Is an Inducible Antimicrobial Peptide Expressed in the Epithelia of Multiple Organs by BALS, R, XIAORONG WANG, MEEGALLA, R. L, WATTLER, S, WEINER, D. J, NEHLS, M. C, WILSON, J. M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Construction of gene targeting vectors from lambda KOS genomic libraries by Wattler, S, Kelly, M, Nehls, M

“…We describe a highly redundant murine genomic library in a new lambda phage, lambda knockout shuttle (lambda KOS) that facilitates the very rapid construction…”
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Identification of a Mammalian Angiopoietin-Related Protein Expressed Specifically in Liver by Conklin, Darrell, Gilbertson, Debra, Taft, David W., Maurer, Mark F., Whitmore, Theodore E., Smith, Deborah L., Walker, Kathleen M., Chen, Lennie H., Wattler, Sigrid, Nehls, Michael, Lewis, Kenneth B.

“…Based on searches of EST databases for signal sequences and amphipathic helices, we have identified and cloned an angiopoietin-like gene, ANGPTL3. Multiple…”
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Random mutagenesis in the mouse as a tool in drug discovery by Russ, Andreas, Stumm, Gabriele, Augustin, Martin, Sedlmeier, Reinhard, Wattler, Sigrid, Nehls, Michael

“…The flood of raw information generated by large-scale data acquisition technologies in genomics, microarrays and proteomics is changing the early stages of the…”
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N-ethyl-N-nitrosourea-based generation of mouse models for mutant G protein-coupled receptors by Grosse, Johannes, Tarnow, Patrick, Rompler, Holger, Schneider, Boris, Sedlmeier, Reinhard, Huffstadt, Ulrike, Korthaus, Dirk, Nehls, Michael, Wattler, Sigrid, Schoneberg, Torsten, Biebermann, Heike, Augustin, Martin

“…1 Ingenium Pharmaceuticals AG, Martinsried 2 Charité Campus Virchow Klinikum, Institute of Pediatric Endocrinology, Humboldt University, Berlin 3 Institute of…”
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Structure and regulation of the salivary gland secretion protein gene Sgs-1 of Drosophila melanogaster by Roth, G.E, Wattler, S, Bornschein, H, Lehmann, M, Korge, G

“…The Drosophila melanogaster gene Sgs-1 belongs to the secretion protein genes, which are coordinately expressed in salivary glands of third instar larvae…”
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Cloning, Chromosomal Location, and Expression Analysis of Murine Smarce1-Related, a New Member of the High-Mobility 365 Group Gene Family by Wattler, Frank, Wattler, Sigrid, Kelly, Mike, Skinner, Henry B., Nehls, Michael

“…Proteins containing high-mobility group (HMG) domains are segregated into two major groups. Members of one group are identified by the presence of more than…”
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