Search Results - "Watters, Dianne J"
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Ferritin functions as a proinflammatory cytokine via iron‐independent protein kinase C zeta/nuclear factor kappaB–regulated signaling in rat hepatic stellate cells
Published in Hepatology (Baltimore, Md.) (01-03-2009)“…Circulating ferritin levels reflect body iron stores and are elevated with inflammation in chronic liver injury. H‐ferritin exhibits a number of extrahepatic…”
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2
Neurodegeneration in ataxia‐telangiectasia: Multiple roles of ATM kinase in cellular homeostasis
Published in Developmental dynamics (01-01-2018)“…Ataxia‐telangiectasia (A‐T) is characterized by neuronal degeneration, cancer, diabetes, immune deficiency, and increased sensitivity to ionizing radiation…”
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3
Ascidian Toxins with Potential for Drug Development
Published in Marine drugs (13-05-2018)“…Ascidians (tunicates) are invertebrate chordates, and prolific producers of a wide variety of biologically active secondary metabolites from cyclic peptides to…”
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4
The CIMP Phenotype in BRAF Mutant Serrated Polyps from a Prospective Colonoscopy Patient Cohort
Published in Gastroenterology research and practice (01-01-2014)“…Colorectal cancers arising via the serrated pathway are often associated with BRAF V600E mutation, CpG island methylator phenotype (CIMP), and microsatellite…”
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5
Calpain activation is upstream of caspases in radiation-induced apoptosis
Published in Cell death and differentiation (01-12-1998)“…The molecular events involved in apoptosis induced by ionizing radiation remain unresolved. In this paper we show that the cleavage of fodrin to a 150 kDa…”
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Undergraduate biochemistry student difficulties with topics requiring mathematical skills: use of an online maths skills support site
Published in Journal of biological education (15-03-2022)“…A number of areas of difficulty in basic numeracy and mathematical skills were identified, which hinder students' success in a foundational biochemistry…”
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7
Online quiz for STEM assumed knowledge self-assessment by first year science students: a pilot study
Published in International journal of mathematical education in science and technology (28-05-2023)“…This study aimed to adapt the Get Set2 quiz and design a diagnostic quiz for implementation under assumed knowledge admissions into university science degrees…”
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8
Heteroatom‐Interchanged Isomers of Lissoclinamide 5: Copper(II) Complexation, Halide Binding, and Biological Activity
Published in European journal of organic chemistry (29-03-2018)“…Cyclic peptides, especially those produced by marine cyanobacteria symbionts, are considered to play an important ecological role in host defence. Chemists…”
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Approaches to Learning by Students in the Biological Sciences: Implications for Teaching
Published in International journal of science education (15-01-2007)“…This study is an investigation of the epistemological beliefs and study habits of students undertaking first-year courses in Biological Chemistry and…”
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10
Iron loading and oxidative stress in the Atm-/- mouse liver
Published in American journal of physiology: Gastrointestinal and liver physiology (01-04-2011)“…Ataxia-Telangiectasia (A-T) is an autosomal recessive disorder resulting in a myriad of abnormalities, including progressive neurodegeneration and cancer…”
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11
An Investigation into Student Perceptions towards Mathematics and Their Performance in First Year Chemistry: Introduction of Online Maths Skills Support
Published in Chemistry education research and practice (01-01-2016)“…An online Maths Skills Site was developed as an integrated support programme for first year Chemistry students, the content of which, was based on an analysis…”
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12
Oxidative stress in ataxia telangiectasia
Published in Redox report : communications in free radical research (01-01-2003)“…Ataxia telangiectasia is one of a group of recessive hereditary genomic instability disorders and is characterized by progressive neurodegeneration,…”
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13
Student understanding of pH: “i don't know what the log actually is, i only know where the button is on my calculator”
Published in Biochemistry and molecular biology education (01-07-2006)“…In foundation biochemistry and biological chemistry courses, a major problem area that has been identified is students' lack of understanding of pH, acids,…”
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14
Resistance to radiation-induced apoptosis in Burkitt's lymphoma cells is associated with defective ceramide signaling
Published in Cancer research (Chicago, Ill.) (15-08-1997)“…Increased sensitivity to ionizing radiation has been shown to be due to defects in double-strand break repair and mutations in the proteins that detect DNA…”
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15
Critical targets of protein kinase C in differentiation of tumour cells
Published in Biochemical pharmacology (01-08-1999)“…The ultimate target of pharmacological research is to find new drugs for treating human diseases such as cancer. Agents causing differentiation and thus growth…”
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16
Sub-structure syntheses and relative stereochemistry in the bistramide (bistratene) series of marine metabolites
Published in Tetrahedron letters (14-01-2002)“…The (6 R*,9 S*,11 S*) and (22 S*,23 R*,27 R*,31 R*) stereochemistry, respectively, of the tetrahydropyranyl and spiroacetal moieties in bistramide A ( 1 ) have…”
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17
Stimulation of protein kinase C-dependent and -independent signaling pathways by bistratene A in intestinal epithelial cells
Published in Biochemical pharmacology (01-05-2001)“…The marine toxin bistratene A (BisA) potently induces cytostasis and differentiation in a variety of systems. Evidence that BisA is a selective activator of…”
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18
Ferritin functions as a proinflammatory cytokine via iron-independent PKC-ζ/NFκB-regulated signalling in rat hepatic stellate cells
Published in Hepatology (Baltimore, Md.) (01-03-2009)“…Circulating ferritin levels reflect body iron stores and are elevated with inflammation in chronic liver injury. H-ferritin exhibits a number of extrahepatic…”
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19
Radioresistant Burkitt's lymphoma cells exhibit defective mapk signalling: Apoptosis and Cell Death
Published in Drug development research (2001)Get full text
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20
Bistratene A Induces a Microtubule-Dependent Block in Cytokinesis and Altered Stathmin Expression in HL60 Cells
Published in Biochemical and biophysical research communications (24-06-1999)“…Bistratene A is a cyclic polyether which affects cell cycle progression and can induce phosphorylation of cellular proteins. Treatment of HL60 cells with 100…”
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