Search Results - "Wattel, Alice"
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High extracellular inorganic phosphate concentration inhibits RANK-RANKL signaling in osteoclast-like cells
Published in Journal of cellular physiology (01-04-2008)“…In this work, we investigated the effect of inorganic phosphate (Pi) on the differentiation of monocyte/macrophage precursors into an “osteoclastic” phenotype,…”
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Stimulatory effect of naturally occurring flavonols quercetin and kaempferol on alkaline phosphatase activity in MG-63 human osteoblasts through ERK and estrogen receptor pathway
Published in Biochemical pharmacology (01-04-2004)“…Many plant-derived substances have estrogenic activities. Due to their ability to bind the estrogen receptor (ER), these compounds have the potential to…”
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Potent inhibitory effect of naturally occurring flavonoids quercetin and kaempferol on in vitro osteoclastic bone resorption
Published in Biochemical pharmacology (2003)“…Several recent studies have suggested that flavonols, a class of phytochemicals with many biological activities, might exert a protective effect against…”
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The Calcium-sensing Receptor Is Involved in Strontium Ranelate-induced Osteoclast Apoptosis
Published in The Journal of biological chemistry (02-01-2009)“…Strontium ranelate exerts both an anti-catabolic and an anabolic effect on bone cells. To further investigate the molecular mechanism whereby strontium…”
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Calcium-sensing Receptor Is Involved in Strontium Ranelate-induced Osteoclast Apoptosis: NEW INSIGHTS INTO THE ASSOCIATED SIGNALING PATHWAYS
Published in The Journal of biological chemistry (02-01-2009)“…Strontium ranelate exerts both an anti-catabolic and an anabolic effect on bone cells. To further investigate the molecular mechanism whereby strontium…”
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Strontium ranelate decreases receptor activator of nuclear factor-ΚB ligand-induced osteoclastic differentiation in vitro: involvement of the calcium-sensing receptor
Published in Molecular pharmacology (01-10-2010)“…Strontium ranelate exerts both an anticatabolic and an anabolic effect on bone cells. To further investigate the mechanism by which strontium ranelate inhibits…”
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Flavonoid quercetin decreases osteoclastic differentiation induced by RANKL via a mechanism involving NFκB and AP-1
Published in Journal of cellular biochemistry (15-05-2004)“…Flavonoids are micronutrients widely present in food of plant origin. They have been attributed pharmacological properties such as anticancer and prevention of…”
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Partnership between academic research and industry to study a new anti-osteoporotic drug
Published in M.S. Médecine sciences (01-06-2005)“…The activity of the osteoclast, the cell responsible for bone resorption, is subjected to different regulation factors. Amongst these, those issued from the…”
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