Search Results - "Watt, Fiona E."

Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management by Marshall, Michelle, Watt, Fiona E., Vincent, Tonia L., Dziedzic, Krysia

“…Osteoarthritis (OA) is a highly prevalent condition, and the hand is the most commonly affected site. Patients with hand OA frequently report symptoms of pain,…”
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Bone Angiogenesis and Vascular Niche Remodeling in Stress, Aging, and Diseases by Stucker, Sina, Chen, Junyu, Watt, Fiona E, Kusumbe, Anjali P

“…The bone marrow (BM) vascular niche microenvironments harbor stem and progenitor cells of various lineages. Bone angiogenesis is distinct and involves…”
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Could sex-specific subtypes of hand osteoarthritis exist? A retrospective study in women presenting to secondary care by Gulati, Malvika, Brewer, Gretchen, Judge, Andrew, Kennedy, Donna, Vincent, Tonia L, Watt, Fiona E

“…Hand osteoarthritis is more common in women, and its risk increases around the time of the menopause. We set out to describe the timing between menopause and…”
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A mixed-methods approach exploring acceptability and feasibility of trials designed to test drugs targeting prevention of post-traumatic osteoarthritis after knee injury by Kalsoum, Raneem, Minns Lowe, Catherine J, Gilbert, Sophie, McCaskie, Andrew W, Snow, Martyn, Wright, Karina, Bruce, Geoff, Mason, Deborah J, Watt, Fiona E

“…To explore key stakeholder views around feasibility and acceptability of trials seeking to prevent post-traumatic osteoarthritis (PTOA) following knee injury,…”
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Posttraumatic osteoarthritis: what have we learned to advance osteoarthritis? by Watt, Fiona E.

“…PURPOSE OF REVIEWCurrent thinking in the study of posttraumatic osteoarthritis (PTOA) is overviewedthe osteoarthritis which follows acute joint injury. The…”
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Toward designing human intervention studies to prevent osteoarthritis after knee injury: A report from an interdisciplinary OARSI 2023 workshop by Whittaker, Jackie L., Kalsoum, Raneem, Bilzon, James, Conaghan, Philip G., Crossley, Kay, Dodge, George R., Getgood, Alan, Li, Xiaojuan, Losina, Elena, Mason, Deborah J., Pietrosimone, Brian, Risberg, May Arna, Roemer, Frank, Felson, David, Culvenor, Adam G., Meuffels, Duncan, Gerwin, Nicole, Simon, Lee S., Lohmander, L. Stefan, Englund, Martin, Watt, Fiona E.

“…The global impact of osteoarthritis is growing. Currently no disease modifying osteoarthritis drugs/therapies exist, increasing the need for preventative…”
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Prevention of posttraumatic osteoarthritis at the time of injury: Where are we now, and where are we going? by Mason, Deborah, Englund, Martin, Watt, Fiona E.

“…This overview of progress made in preventing post‐traumatic osteoarthritis (PTOA) was delivered in a workshop at the Orthopaedics Research Society Annual…”
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Hand osteoarthritis, menopause and menopausal hormone therapy by Watt, Fiona E

“…Highlights • The clinical importance of symptomatic hand OA in post-menopausal women is highlighted. • The evidence for an association between the menopause…”
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The use of technology in the subcategorisation of osteoarthritis: a Delphi study approach by Mennan, Claire, Hopkins, Timothy, Channon, Alastair, Elliott, Mark, Johnstone, Brian, Kadir, Timor, Loughlin, John, Peffers, Mandy, Pitsillides, Andrew, Sofat, Nidhi, Stewart, Caroline, Watt, Fiona E., Zeggini, Eleftheria, Holt, Cathy, Roberts, Sally

“…This UK-wide OATech Network + consensus study utilised a Delphi approach to discern levels of awareness across an expert panel regarding the role of existing…”
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Cartilage Repair Activity during Joint-Preserving Treatment May Be Accompanied by Osteophyte Formation by Jansen, Mylène P., Mastbergen, Simon C., Watt, Fiona E., Willemse, Elske J., Vincent, Tonia L., Spruijt, Sander, Emans, Pieter J., Custers, Roel J. H., van Heerwaarden, Ronald J., Lafeber, Floris P. J. G.

“…Knee joint distraction (KJD) treatment has shown cartilage repair and clinical improvement in patients with osteoarthritis, as has high tibial osteotomy (HTO)…”
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Hand Osteoarthritis: investigating Pain Effects of estrogen-containing therapy (HOPE-e): a protocol for a feasibility randomised placebo-controlled trial by Marian, Ioana R, Goff, Megan, Williams, Jennifer A E, Gulati, Malvika, Chester-Jones, Mae, Francis, Anne, Watson, Marion, Vincent, Tonia L, Woollacott, Sue, Mackworth-Young, Charles, Glover, Victoria, Furniss, Dominic, Gardiner, Matthew, Lamb, Sarah E, Vincent, Katy, Barber, Vicki S, Black, Joanna, Dutton, Susan J, Watt, Fiona E

“…Hand osteoarthritis (OA) is a common condition, causing pain, stiffness and reduced quality of life. Incidence is higher amongst women, particularly around the…”
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Development of medical therapeutics in osteoarthritis: time for action to improve patient care by Sofat, Nidhi, Watt, Fiona E, Tan, Ai Lyn

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Osteoarthritis and associated comorbidities: new answers and more questions by Watt, Fiona E, Wise, Elspeth M

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Acute Molecular Changes in Synovial Fluid Following Human Knee Injury: Association With Early Clinical Outcomes by Watt, Fiona E., Paterson, Erin, Freidin, Andrew, Kenny, Mark, Judge, Andrew, Saklatvala, Jeremy, Williams, Andy, Vincent, Tonia L.

“…Objective To investigate whether molecules found to be up‐regulated within hours of surgical joint destabilization in the mouse are also elevated in the…”
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Making the most of the waiting room: Electronic patient engagement, a mixed methods study by Coathup, Victoria, Finlay, Teresa, Teare, Harriet JA, Kaye, Jane, South, Matthew, Watt, Fiona E, Luqmani, Raashid

“…Objective The purpose of this study was to explore whether patients with musculoskeletal conditions would agree to use digital technologies to learn about…”
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The Effect of Acute Knee Injuries and Related Knee Surgery on Serum Levels of Pro- and Anti-inflammatory Lipid Mediators and Their Associations With Knee Symptoms by Turnbull, James, Jha, Rakesh R., Barrett, David A., Valdes, Ana M., Alderson, Jennifer, Williams, Andrew, Vincent, Tonia L., Watt, Fiona E., Chapman, Victoria

“…Background: Despite an acute knee injury being a major risk factor for osteoarthritis, the factors that initiate and maintain this risk of longer-term knee…”
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Hydroxychloroquine Effectiveness in Reducing Symptoms of Hand Osteoarthritis: A Randomized Trial by Kingsbury, Sarah R, Tharmanathan, Puvan, Keding, Ada, Ronaldson, Sarah J, Grainger, Andrew, Wakefield, Richard J, Arundel, Catherine, Birrell, Fraser, Doherty, Michael, Vincent, Tonia, Watt, Fiona E, Dziedzic, Krysia, O'Neill, Terence W, Arden, Nigel K, Scott, David L, Dickson, John, Garrood, Toby, Green, Michael, Menon, Ajit, Sheeran, Tom, Torgerson, David, Conaghan, Philip G

“…Synovitis is believed to play a role in producing symptoms in persons with hand osteoarthritis, but data on slow-acting anti-inflammatory treatments are…”
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The influence of sex hormones on musculoskeletal pain and osteoarthritis by Gulati, Malvika, Dursun, Eren, Vincent, Katy, Watt, Fiona E

“…The association of female sex with certain rheumatic symptoms and diseases is now indisputable. Some of the most striking examples of this association occur in…”
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Association of serum biomarkers with radiographic knee osteoarthritis, knee pain and function in a young, male, trauma-exposed population – Findings from the ADVANCE study by O’Sullivan, Oliver, Stocks, Joanne, Schofield, Susie, Bilzon, James, Boos, Christopher J., Bull, Anthony M.J., Fear, Nicola T., Watt, Fiona E., Bennett, Alexander N., Kluzek, Stefan, Valdes, Ana M.

“…The ArmeD SerVices TrAuma RehabilitatioN OutComE (ADVANCE) study is investigating long-term combat-injury outcomes; this sub-study aims to understand the…”
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Artificial intelligence in osteoarthritis: repair by knee joint distraction shows association of pain, radiographic and immunological outcomes by Jansen, Mylène P, Salzlechner, Christoph, Barnes, Eleanor, DiFranco, Matthew D, Custers, Roel J H, Watt, Fiona E, Vincent, Tonia L, Mastbergen, Simon C

“…Abstract Objectives Knee joint distraction (KJD) has been associated with clinical and structural improvement and SF marker changes. The current objective was…”
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