Search Results - "Watson, Rachel"

Molecular aspects of skin ageing by Naylor, Elizabeth C, Watson, Rachel E.B, Sherratt, Michael J

“…Abstract Ageing of human skin may result from both the passage of time (intrinsic ageing) and from cumulative exposure to external influences (extrinsic…”
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Inflammaging and the Skin by Pilkington, Suzanne M., Bulfone-Paus, Silvia, Griffiths, Christopher E.M., Watson, Rachel E.B.

“…As global life expectancy continues to rise, we are challenged with maintaining health into old age. One strategy is to target the chronic low-level…”
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Skin ageing and topical rejuvenation strategies by Griffiths, Tamara W, Watson, Rachel E B, Langton, Abigail K

“…Abstract Skin ageing is a complex process involving the additive effects of skin’s interaction with its external environment, predominantly chronic sun…”
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Age-Associated Skin Conditions and Diseases: Current Perspectives and Future Options by Blume-Peytavi, Ulrike, Kottner, Jan, Sterry, Wolfram, Hodin, Michael W, Griffiths, Tamara W, Watson, Rachel E B, Hay, Roderick J, Griffiths, Christopher E M

“…The International League of Dermatological Societies (ILDS), a global, not-for-profit organization representing 157 dermatological societies worldwide, has…”
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Menopause induces changes to the stratum corneum ceramide profile, which are prevented by hormone replacement therapy by Kendall, Alexandra C., Pilkington, Suzanne M., Wray, Jonathan R., Newton, Victoria L., Griffiths, Christopher E. M., Bell, Mike, Watson, Rachel E. B., Nicolaou, Anna

“…The menopause can lead to epidermal changes that are alleviated by hormone replacement therapy (HRT). We hypothesise that these changes could relate to altered…”
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Expanding growers' choice of plant disease management options can promote suboptimal social outcomes by Murray‐Watson, Rachel E., Cunniffe, Nik J.

“…Previous models of growers' decision‐making during epidemics have unrealistically limited disease management choices to just two options. Here, we expand…”
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Damage to skin extracellular matrix induced by UV exposure by Watson, Rachel E B, Gibbs, Neil K, Griffiths, Christopher E M, Sherratt, Michael J

“…Chronic exposure to environmental ultraviolet radiation (UVR) plays a key role in both photocarcinogenesis and induction of accelerated skin aging. Although…”
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Ageing significantly impacts the biomechanical function and structural composition of skin by Langton, Abigail K., Graham, Helen K., Griffiths, Christopher E. M., Watson, Rachel E. B.

“…Skin ageing is a complex process involving the additive effects of skin's interaction with its external environment, predominantly chronic sun exposure, upon a…”
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Peptide location fingerprinting reveals modification‐associated biomarker candidates of ageing in human tissue proteomes by Ozols, Matiss, Eckersley, Alexander, Mellody, Kieran T., Mallikarjun, Venkatesh, Warwood, Stacey, O'Cualain, Ronan, Knight, David, Watson, Rachel E. B., Griffiths, Christopher E. M., Swift, Joe, Sherratt, Michael J.

“…Although dysfunctional protein homeostasis (proteostasis) is a key factor in many age‐related diseases, the untargeted identification of structurally modified…”
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How the epidemiology of disease-resistant and disease-tolerant varieties affects grower behaviour by Murray-Watson, Rachel E, Cunniffe, Nik J

“…Population-scale effects of resistant or tolerant crop varieties have received little consideration from epidemiologists. When growers deploy tolerant crop,…”
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Structural and compositional diversity of fibrillin microfibrils in human tissues by Eckersley, Alexander, Mellody, Kieran T., Pilkington, Suzanne, Griffiths, Christopher E.M., Watson, Rachel E.B., O’Cualain, Ronan, Baldock, Clair, Knight, David, Sherratt, Michael J.

“…Elastic fibers comprising fibrillin microfibrils and elastin are present in many tissues, including the skin, lungs, and arteries, where they confer elasticity…”
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A randomized controlled trial of green tea catechins in protection against ultraviolet radiation-induced cutaneous inflammation by Farrar, Mark D, Nicolaou, Anna, Clarke, Kayleigh A, Mason, Sarah, Massey, Karen A, Dew, Tristan P, Watson, Rachel E B, Williamson, Gary, Rhodes, Lesley E

“…Safe systemic protection from the health hazards of ultraviolet radiation (UVR) in sunlight is desirable. Green tea is consumed globally and is reported to…”
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Remodelling of fibrillin-rich microfibrils by solar-simulated radiation: impact of skin ethnicity by Langton, Abigail K, Hann, Mark, Costello, Patrick, Halai, Poonam, Griffiths, Christopher E M, Sherratt, Michael J, Watson, Rachel E B

“…Fibrillin-rich microfibrils (FRMs) constitute integral components of the dermal elastic fibre network with a distinctive ultrastructural 'beads-on-a-string'…”
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Frontiers in translational systemic sclerosis research: A focus on the unmet 'cutaneous' clinical needs (Viewpoint) by Herrick, Ariane L., Shukla, Rudresh, Watson, Rachel E. B.

“…This viewpoint considers four cutaneous unmet clinical needs of patients with systemic sclerosis (SSc), namely the rapidly progressive skin thickening…”
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The Averted Gaze: Audre Lorde’s Zami and the Death of Emmett Till by Watson, Rachel

“…This essay considers Audre Lorde’s Zami: A New Spelling of My Name (1982) as an example of the neoliberal turn to memoir that both complicates and exemplifies…”
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Fractional Sunburn Threshold UVR Doses Generate Equivalent Vitamin D and DNA Damage in Skin Types I–VI but with Epidermal DNA Damage Gradient Correlated to Skin Darkness by Shih, Barbara B., Farrar, Mark D., Cooke, Marcus S., Osman, Joanne, Langton, Abigail K., Kift, Richard, Webb, Ann R., Berry, Jacqueline L., Watson, Rachel E.B., Vail, Andy, de Gruijl, Frank R., Rhodes, Lesley E.

“…Public health guidance recommends limiting sun exposure to sub-sunburn levels, but it is unknown whether these can gain vitamin D (for musculoskeletal health)…”
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Dynamics of the human skin mediator lipidome in response to dietary ω‐3 fatty acid supplementation by Kendall, Alexandra C., Pilkington, Suzanne M., Murphy, Sharon A., Carratore, Francesco Del, Sunarwidhi, Anggit L., Kiezel‐Tsugunova, Magdalena, Urquhart, Paula, Watson, Rachel E. B., Breitling, Rainer, Rhodes, Lesley E., Nicolaou, Anna

“…Nutritional supplementation with fish oil or ω‐3 (n‐3) polyunsaturated fatty acids (PUFAs) has potential benefits for skin inflammation. Although the…”
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Prediction, screening and characterization of novel bioactive tetrapeptide matrikines for skin rejuvenation by Jariwala, Nathan, Ozols, Matiss, Eckersley, Alexander, Mambwe, Bezaleel, Watson, Rachel E B, Zeef, Leo, Gilmore, Andrew, Debelle, Laurent, Bell, Mike, Bradley, Eleanor J, Doush, Yegor, Keenan, Amy, Courage, Carole, Leroux, Richard, Peschard, Olivier, Mondon, Philippe, Ringenbach, Caroline, Bernard, Laure, Pitois, Aurelien, Sherratt, Michael J

“…Extracellular matrices play a critical role in tissue structure and function and aberrant remodelling of these matrices is a hallmark of many age-related…”
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Oral green tea catechin metabolites are incorporated into human skin and protect against UV radiation-induced cutaneous inflammation in association with reduced production of pro-inflammatory eicosanoid 12-hydroxyeicosatetraenoic acid by Rhodes, Lesley E., Darby, Gemma, Massey, Karen A., Clarke, Kayleigh A., Dew, Tristan P., Farrar, Mark D., Bennett, Susan, Watson, Rachel E. B., Williamson, Gary, Nicolaou, Anna

“…Green tea catechins (GTC) reduce UV radiation (UVR)-induced inflammation in experimental models, but human studies are scarce and their cutaneous…”
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The impact of intrinsic ageing on the protein composition of the dermal-epidermal junction by Langton, Abigail K., Halai, Poonam, Griffiths, Christopher E.M., Sherratt, Michael J., Watson, Rachel E.B.

“…The dermal-epidermal junction of human skin exhibits age-related remodelling, resulting in a flattened appearance and reduced surface area. Despite this, a…”
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