Search Results - "Watson, JD"

ProFunc: a server for predicting protein function from 3D structure by Laskowski, Roman A., Watson, James D., Thornton, Janet M.

“…ProFunc (http://www.ebi.ac.uk/thornton-srv/databases/ProFunc) is a web server for predicting the likely function of proteins whose 3D structure is known but…”
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A direct demonstration of functional specialization in human visual cortex by Zeki, S, Watson, JD, Lueck, CJ, Friston, KJ, Kennard, C, Frackowiak, RS

“…We have used positron emission tomography (PET), which measures regional cerebral blood flow (rCBF), to demonstrate directly the specialization of function in…”
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Predicting protein function from sequence and structural data by Watson, James D, Laskowski, Roman A, Thornton, Janet M

“…When a protein's function cannot be experimentally determined, it can often be inferred from sequence similarity. Should this process fail, analysis of the…”
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Protein Function Prediction Using Local 3D Templates by Laskowski, Roman A., Watson, James D., Thornton, Janet M.

“…The prediction of a protein's function from its 3D structure is becoming more and more important as the worldwide structural genomics initiatives gather pace…”
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Passion for DNA: Genes, Genomes, and Society by Watson, James D, Gratzer, Walter

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A novel main-chain anion-binding site in proteins: the nest. A particular combination of phi,psi values in successive residues gives rise to anion-binding sites that occur commonly and are found often at functionally important regions by Watson, James D, Milner-White, E James

“…Main-chain conformations where one amino acid residue can be described as gamma(R) (or alpha(R)) and an adjacent one as gamma(L) (or alpha(L)) mostly result in…”
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A Study of Multimodal Motherese: The Role of Temporal Synchrony between Verbal Labels and Gestures by Gogate, Lakshmi J., Bahrick, Lorraine E., Watson, Jilayne D.

“…This study examined European American and Hispanic American mothers' multimodal communication to their infants (N = 24). The infants were from three age groups…”
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Infection in permanent circulatory support: experience from the REMATCH trial by Holman, William L, Park, Soon J, Long, James W, Weinberg, Alan, Gupta, Lopa, Tierney, Anita R, Adamson, Robert M, Watson, John D, Raines, Edward P, Couper, Gregory S, Pagani, Francis D, Burton, Nelson A, Miller, Leslie W, Naka, Yoshifumi

“…This analysis of the REMATCH Trial focuses on infection, which was an important source of morbidity and mortality. We use the information to suggest ways to…”
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Identification of a new fibroblast growth factor receptor, FGFR5 by Sleeman, Matthew, Fraser, Jonathan, McDonald, Megan, Yuan, Shining, White, Damian, Grandison, Prudence, Kumble, Krishnanand, Watson, James D., Murison, J.Greg

“…A novel fibroblast growth factor receptor (FGFR), designated FGFR5, was identified from an EST database of a murine lymph node stromal cell cDNA library. The…”
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Analysis of Myc Bound Loci Identified by CpG Island Arrays Shows that Max Is Essential for Myc-Dependent Repression by Mao, Daniel Y.L., Watson, John D., Yan, Pearlly S., Barsyte-Lovejoy, Dalia, Khosravi, Fereshteh, Wong, W.Wei-Lynn, Farnham, Peggy J., Huang, Tim H.-M., Penn, Linda Z.

“…The c-myc proto-oncogene encodes a transcription factor, c-Myc, which is deregulated and/or overexpressed in many human cancers. Despite c-Myc's importance,…”
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Identifying Genes Regulated in a Myc-dependent Manner by Watson, John D., Oster, Sara K., Shago, Mary, Khosravi, Fereshteh, Penn, Linda Z.

“…The c-myc proto-oncogene can direct a diverse array of biological activities, including cell cycle progression, apoptosis, and differentiation. It is believed…”
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The Shwachman-Bodian-Diamond Syndrome Protein Family Is Involved in RNA Metabolism by Savchenko, Alexei, Krogan, Nevan, Cort, John R., Evdokimova, Elena, Lew, Jocelyne M., Yee, Adelinda A., Sánchez-Pulido, Luis, Andrade, Miguel A., Bochkarev, Alexey, Watson, James D., Kennedy, Michael A., Greenblatt, Jack, Hughes, Timothy, Arrowsmith, Cheryl H., Rommens, Johanna M., Edwards, Aled M.

“…A combination of structural, biochemical, and genetic studies in model organisms was used to infer a cellular role for the human protein (SBDS) responsible for…”
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Cloning of a T Cell Growth Factor That Interacts with the β Chain of the Interleukin-2 Receptor by Grabstein, Kenneth H., Eisenman, June, Shanebeck, Kurt, Rauch, Charles, Srinivasan, Subhashini, Fung, Victor, Beers, Courtney, Richardson, Jane, Schoenborn, Michael A., Ahdieh, Minoo, Johnson, Lisabeth, Alderson, Mark R., Watson, James D., Anderson, Dirk M., Giri, Judith G.

“…A cytokine was identified that stimulated the proliferation of T lymphocytes, and a complementary DNA clone encoding this new T cell growth factor was…”
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Cloning and Biological Activity of Epigen, a Novel Member of the Epidermal Growth Factor Superfamily by Strachan, Lorna, Murison, J. Greg, Prestidge, Ross L., Sleeman, Matthew A., Watson, James D., Kumble, Krishnanand D.

“…High throughput sequencing of a mouse keratinocyte library was used to identify an expressed sequence tag with homology to the epidermal growth factor (EGF)…”
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Hidradenitis suppurativa--a clinical review by Watson, J D

“…A retrospective review of 72 patients suffering from hidradenitis suppurativa treated surgically in one plastic surgery unit has been carried out. Treatment of…”
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Treatment of angina pectoris in the community: is medical therapy given a chance? by Kee, F, Gaffney, B, Canavan, C, Little, J, McConnell, W, Telford, AM, Watson, JD

“…To describe the routine management of patients with chronic stable angina by GPs in Northern Ireland and the factors which they perceived affected the success…”
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The conformations of polypeptide chains where the main-chain parts of successive residues are enantiomeric. Their occurrence in cation and anion-binding regions of proteins by Watson, James D, Milner-White, E James

“…We have investigated the shapes of polypeptides where successive residues have main-chain phi,psi conformations of opposite hand. A graph not unlike a…”
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CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells by MORRISSEY, P. J, CHARRIER, K, BRADDY, S, LIGGITT, D, WATSON, J. D

“…Purified CD4+ lymph node T cells were sorted into two populations on the basis of their expression of CD45RB (CD45RBhi and CD45RBlo) and injected into congenic…”
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Crystal Structure of Enterococcus faecalis SlyA-like Transcriptional Factor by Wu, Rui-Ying, Zhang, Rong-Guang, Zagnitko, Olga, Dementieva, Irina, Maltzev, Natalia, Watson, James D., Laskowski, Roman, Gornicki, Piotr, Joachimiak, Andrzej

“…The crystal structure of a SlyA transcriptional regulator at 1.6 Å resolution is presented, and structural relationships between members of the MarR/SlyA…”
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Genetic discrimination: time to act by Collins, Francis S, Watson, James D

“…Collins and Watson stress the need for the U.S. House of Representative to approve the Genetic Information Nondiscrimination Act of 2003 that would protect…”
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