Search Results - "Watson, J.N"

Shock outcome prediction before and after CPR: A comparative study of manual and automated active compression–decompression CPR by Box, M.S, Watson, J.N, Addison, P.S, Clegg, G.R, Robertson, C.E

“…Summary We report on a study designed to compare the relative efficacy of manual CPR (M-CPR) and automated mechanical CPR (ACD-CPR) provided by an active…”
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Wavelet transform analysis predicts outcome of DC cardioversion for atrial fibrillation patients by Watson, J.N, Addison, P.S, Uchaipichat, N, Shah, A.S, Grubb, N.R

“…Abstract The aim of this study was to examine whether wavelet transform analysis of the electrocardiogram (ECG) can improve the prediction of the maintenance…”
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The De‐Noising of Sonic Echo Test Data through Wavelet Transform Reconstruction by Watson, J.N., Addison, P.S., Sibbald, A.

“…This paper presents the results of feasibility study into the application of the wavelet transform signal processing method to sonic based non‐destructive…”
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Process Research and Scale-up of the κ-Opioid Receptor Agonist CJ-15,161 Drug Candidate by Brian M. Andresen, Brian C. Vanderplas, John L. Tucker, Janice E. Sieser, Maxime Riou, Teresa M. Makowski, Joel M. Hawkins, Melina Girardin, Arun Ghosh, Kristina Dupont-Gaudet, Nga M. Do, Keith M. DeVries, Michel Couturier, Stéphane Caron, Timothy J.N. Watson

“…This account depicts strategies adopted during the development of the κ-opioid receptor agonist CJ-15,161. While the original discovery synthesis was enabled…”
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LOW-OSCILLATION COMPLEX WAVELETS by ADDISON, P.S., WATSON, J.N., FENG, T.

“…In this paper we explore the use of two low-oscillation complex wavelets—Mexican hat and Morlet—as powerful feature detection tools for data analysis. These…”
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Evaluating arrhythmias in ECG signals using wavelet transforms by Addison, P.S., Watson, J.N., Clegg, G.R., Holzer, M., Sterz, F., Robertson, C.E.

“…Recent work has attempted to utilize wavelet techniques in the analysis of biomedical signals including ECGs. Here, the authors present an energy-based method…”
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T-Wave Alternans Found in Preventricular Tachyarrhythmias in CCU Patients Using a Wavelet Transform-Based Methodology by Romero, Inaki, Grubb, Neil R., Clegg, Gareth R., Robertson, Colin E., Addison, Paul S., Watson, James N.

“…Ventricular tachyarrhythmias are potentially lethal cardiac pathologies and the commonest cause of sudden cardiac death. Efforts to predict the onset of such…”
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Finding coordinated atrial activity during ventricular fibrillation using wavelet decomposition by Addison, P.S., Watson, J.N., Clegg, G.R., Steen, P.A., Robertson, C.E.

“…Until recently, the ECG recorded during ventricular fibrillation was thought to represent disorganized and unstructured electrical activity of the heart. Using…”
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The Synthesis and Crystal Structure of Doped Uranium Brannerite Phases U1−xMxTi2O6 (M=Ca2+, La3+, and Gd3+) by James, M., Watson, J.N.

“…Doped uranium brannerite phases (U1−xMxTi2O6; M=Ca2+, La3+ and Gd3+; x<0.5) were synthesized at 1400°C; the range of solid solution was found to vary depending…”
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The synthesis, crystal chemistry and structures of Y-doped brannerite (U 1− xY xTi 2O 6) and thorutite (Th 1− xY xTi 2O 6− δ) phases by James, M., Carter, M.L., Watson, J.N.

“…Yttrium-doped uranium brannerite (U 1− x Y x Ti 2O 6) and thorutite (Th 1− x Y x Ti 2O 6− δ ) phases were synthesized in air at 1400°C. Powder X-ray…”
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Practical issues in the evaluation of methods for the prediction of shock outcome success in out-of-hospital cardiac arrest patients by Watson, J.N., Addison, P.S., Clegg, G.R., Steen, P.A., Robertson, C.E.

“…There is a need for robust, effective predictors of the outcome from shock for out-of-hospital cardiac arrest patients. Such technology would enable the…”
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Asymmetric Catalysis in the Pharmaceutical Industry by Hawkins, Joel M., Watson, Timothy J. N.

“…The best catalyst from a chemical perspective is not necessarily the best catalyst from an overall economic perspective. In competing approaches to candoxatril…”
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The Selection and Control of Starting Materials Should be Governed by Science and Risk-Based Approaches by Watson, Timothy J. N., Nosal, Roger, Lepore, John, Montgomery, Frank

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Misunderstanding Design Space: a Robust Drug Product Control Strategy Is the Key to Quality Assurance by Watson, Timothy J. N., Nosal, Roger, Lepore, John, Montgomery, Frank

“…ICH guidelines Q8/11, Q9, and Q10 introduced risk-based approaches and enhanced scientific understanding as an opportunity to encourage continuous process…”
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Wavelet analysis of pulse oximeter waveform permits identification of unwell children by Leonard, P, Beattie, T F, Addison, P S, Watson, J N

“…Background: Children who are unwell often display signs of circulatory compromise. It has been observed that pronounced changes occur in the appearance of the…”
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Spectral-temporal filtering of NDT data using wavelet transform modulus maxima by Watson, J.N., Addison, P.S.

“…In this paper, a method is described for the filtering of non-destructive testing (NDT) signals. By employing wavelet transform modulus maxima filtering in the…”
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The Use of Glycidyl Ethers Involving Aziridinium Intermediates and Other Methodology for the Preparation of Enantiomerically Pure Drug Candidates by Ayers, Timothy A, Watson, Timothy J. N, Subotkowski, Witold, Daniel, John, Webster, Mark

“…An enantiospecific 1,2-amine migration process through an aziridinium intermediate involving ring-opening with potassium phthalimide derivatives to produce…”
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Secondary wavelet feature decoupling (SWFD) and its use in detecting patient respiration from the photoplethysmogram by Addison, P.S., Watson, J.N.

“…We describe a method for the identification of time-frequency features associated with patient respiration in the wavelet decomposition of the…”
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A Science and Risk Based Proposal for Understanding Scale and Equipment Dependencies of Small Molecule Drug Substance Manufacturing Processes by am Ende, David J., Seymour, Christine B., Watson, Timothy J. N.

“…ICH Q8(R2) established general guidelines around the Relationship of a Design Space to Scale and Equipment (Section 2.4.4); however, the guideline is not…”
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A Design Space Verification Protocol for a Small Molecule Drug Substance by Watson, Timothy J. N., Bonsignore, Holly, Callaghan-Manning, Eileen A., Colgan, Stephen T., Fitzsimons, Paul, Garcia, Thomas P., Groskoph, John G., Lynch, Michael P., Nosal, Roger, McMahon, Megan E., Singer, Robert A., Thomson, Nicholas M., Sluggett, Gregory W., Schulz, Darren J., Twohig, Shirley

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