Search Results - "Watson, E J"
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Phagocytosis increases an oxidative metabolic and immune suppressive signature in tumor macrophages
Published in The Journal of experimental medicine (05-06-2023)“…Phagocytosis is a key macrophage function, but how phagocytosis shapes tumor-associated macrophage (TAM) phenotypes and heterogeneity in solid tumors remains…”
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Anthropogenic modification of forests means only 40% of remaining forests have high ecosystem integrity
Published in Nature communications (08-12-2020)“…Many global environmental agendas, including halting biodiversity loss, reversing land degradation, and limiting climate change, depend upon retaining forests…”
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A pilot study evaluating GSK1070806 inhibition of interleukin-18 in renal transplant delayed graft function
Published in PloS one (08-03-2021)“…Delayed graft function (DGF) following renal transplantation is a manifestation of acute kidney injury (AKI) leading to poor long-term outcome. Current…”
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Defatting of donor transplant livers during normothermic perfusion-a randomised clinical trial: study protocol for the DeFat study
Published in Current controlled trials in cardiovascular medicine (17-06-2024)“…Liver disease is the third leading cause of premature death in the UK. Transplantation is the only successful treatment for end-stage liver disease but is…”
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From “Gut Feeling” to Objectivity: Machine Preservation of the Liver as a Tool to Assess Organ Viability
Published in Current transplantation reports (2018)“…Purpose of Review The purpose of this review was to summarise how machine perfusion could contribute to viability assessment of donor livers. Recent Findings…”
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Spatial priorities for conserving the most intact biodiverse forests within Central Africa
Published in Environmental research letters (01-09-2020)“…The forests of Central Africa contain some of Earth's few remaining intact forests. These forests are increasingly threatened by infrastructure development,…”
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Sphingosine kinase activity is not required for tumor cell viability
Published in PloS one (05-07-2013)“…Sphingosine kinases (SPHKs) are enzymes that phosphorylate the lipid sphingosine, leading to the formation of sphingosine-1-phosphate (S1P). In addition to the…”
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In Situ Normothermic Regional Perfusion for Controlled Donation After Circulatory Death—The United Kingdom Experience
Published in American journal of transplantation (01-12-2014)“…Organs recovered from donors after circulatory death (DCD) suffer warm ischemia before cold storage which may prejudice graft survival and result in a greater…”
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Comparison of equilibrium and non-equilibrium distribution coefficients for the human drug carbamazepine in soil
Published in Chemosphere (Oxford) (2014)“…The distribution coefficient (KD) for the human drug carbamazepine was measured using a non-equilibrium technique. Repacked soil columns were prepared using an…”
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A comprehensive study of chromosome 16q in invasive ductal and lobular breast carcinoma using array CGH
Published in Oncogene (19-10-2006)“…We analysed chromosome 16q in 106 breast cancers using tiling-path array-comparative genomic hybridization (aCGH). About 80% of ductal cancers (IDCs) and all…”
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Author Correction: Anthropogenic modification of forests means only 40% of remaining forests have high ecosystem integrity
Published in Nature communications (20-01-2021)“…A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-20999-7…”
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Changes in quality of life (QoL) and other patient-reported outcome measures (PROMs) in living-donor and deceased-donor kidney transplant recipients and those awaiting transplantation in the UK ATTOM programme: a longitudinal cohort questionnaire survey with additional qualitative interviews
Published in BMJ open (14-04-2021)“…ObjectiveTo examine quality of life (QoL) and other patient-reported outcome measures (PROMs) in kidney transplant recipients and those awaiting…”
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Integration of high-resolution array comparative genomic hybridization analysis of chromosome 16q with expression array data refines common regions of loss at 16q23-qter and identifies underlying candidate tumor suppressor genes in prostate cancer
Published in Oncogene (22-04-2004)“…We have constructed a high-resolution genomic microarray of human chromosome 16q, and used it for comparative genomic hybridization analysis of 16 prostate…”
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Erythropoietin receptor transcription is neither elevated nor predictive of surface expression in human tumour cells
Published in British journal of cancer (25-03-2008)“…Erythropoietin receptor (EpoR) has been reported to be overexpressed in tumours and has raised safety concerns regarding the use of erythropoiesis-stimulating…”
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Donor kidney disease and transplant outcome for kidneys donated after cardiac death
Published in British journal of surgery (01-03-2009)“…Background: Although outcomes of kidney transplants following donation after cardiac death (DCD) and donation after brainstem death (DBD) are similar,…”
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Preimplant Normothermic Liver Perfusion of a Suboptimal Liver Donated After Circulatory Death
Published in American journal of transplantation (01-01-2016)“…Livers retrieved after circulatory death are associated with an increased incidence of primary nonfunction, early allograft dysfunction, and biliary…”
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Organ Transplants From Deceased Donors With Primary Brain Tumors and Risk of Cancer Transmission
Published in JAMA surgery (01-05-2023)“…Cancer transmission is a known risk for recipients of organ transplants. Many people wait a long time for a suitable transplant; some never receive one…”
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Distribution and presentation of Lyme borreliosis in Scotland - analysis of data from a national testing laboratory
Published in The Journal of the Royal College of Physicians of Edinburgh (01-01-2015)“…This study examines the distribution of laboratory-confirmed cases of Lyme borreliosis in Scotland and the clinical spectrum of presentations within NHS…”
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Spring Succession of Necrophilous Insects on Wildlife Carcasses in Louisiana
Published in Journal of medical entomology (01-05-2003)“…Seven fresh animal carcasses were monitored throughout decomposition in a mixed flatwood forest in East Baton Rouge Parish, LA from 1 April to 1 July 1999…”
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