Search Results - "Watson, Cynthia"
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Conditional deletion of Gata3 shows its essential function in TH1-TH2 responses
Published in Nature immunology (01-11-2004)“…Expression of the transcription factor GATA-3 is strongly associated with T helper type 2 (T(H)2) differentiation, but genetic evidence for its involvement in…”
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2
Intrarater and Interrater Reliability of Quantitative Ultrasound Speed of Sound by Trained Raters at the Distal Radius in Postmenopausal Women
Published in Journal of geriatric physical therapy (2001) (01-10-2024)“…Quantitative ultrasound (QUS) performed at the distal radius shows potential as an effective tool for evaluating fracture risk, especially in postmenopausal…”
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Community‐based monitoring, assessment and management of data‐limited inland fish stocks in North Rupununi, Guyana
Published in Fisheries management and ecology (01-04-2023)“…Inland fisheries are important for food security in communities around the world, especially in developing countries. In North Rupununi, Guyana, the state of…”
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Toxins and Other Bioactive Metabolites in Deep Chlorophyll Layers Containing the Cyanobacteria Planktothrix cf. isothrix in Two Georgian Bay Embayments, Lake Huron
Published in Toxins (27-06-2021)“…The understanding of deep chlorophyll layers (DCLs) in the Great Lakes-largely reported as a mix of picoplankton and mixotrophic nanoflagellates-is…”
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5
Efficient cytokine-induced IL-13 production by mast cells requires both IL-33 and IL-3
Published in Journal of allergy and clinical immunology (01-09-2013)“…Background IL-13 is a critical effector cytokine for allergic inflammation. It is produced by several cell types, including mast cells, basophils, and TH 2…”
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6
Prediabetes: Screening, Diagnosis, and Intervention
Published in Journal for nurse practitioners (01-03-2017)“…Prediabetes affects 86 million Americans, predisposing them to type 2 diabetes and cardiovascular disease. Evidence-based guidelines recommend risk factor…”
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Epidemiologic and Genomic Analysis of the Severe Acute Respiratory Syndrome Coronavirus 2 Epidemic in the Nebraska Region of the United States, March 2020-2021
Published in Frontiers in microbiology (18-05-2022)“…COVID-19 emerged at varying intervals in different regions of the United States in 2020. This report details the epidemiologic and genetic evolution of Severe…”
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8
Targeted sequencing for hereditary breast and ovarian cancer in BRCA1/2-negative families reveals complex genetic architecture and phenocopies
Published in HGG advances (18-07-2024)“…Approximately 20% of breast cancer cases are attributed to increased family risk, yet variation in BRCA1/2 can only explain 20%–25% of cases. Historically,…”
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In vitro data suggest a role for PMS2 Kozak sequence mutations in Lynch syndrome risk
Published in HGG advances (18-07-2024)“…Lynch syndrome (LS) is the most common hereditary cancer syndrome. Heterozygous loss-of-function variants in PMS2 are linked to LS. While these variants are…”
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Survey of Methylmercury Exposures and Risk Factors Among Indigenous Communities in Guyana, South America
Published in Journal of health & pollution (01-06-2020)“…Gold mining activities in forested areas across Guyana have been a common practice for more than a century. The intensification of artisanal and small-scale…”
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NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway
Published in Nature immunology (01-12-2000)“…Using a mouse model in which tumors show a growth-regression-recurrence pattern, we investigated the mechanisms for down-regulation of cytotoxic T…”
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12
Stat6 Is Necessary and Sufficient for IL-4's Role in Th2 Differentiation and Cell Expansion
Published in The Journal of immunology (1950) (15-06-2001)“…IL-4 plays a critical role in the differentiation of TCR-stimulated naive CD4 T cells to the Th2 phenotype. In response to IL-4, the IL-4R activates a set of…”
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Complete Genome Sequences of Six Staphylococcus pseudintermedius Strains from Dogs with Superficial Pyoderma in Georgia, USA
Published in Microbiology resource announcements (24-06-2021)“…Staphylococcus pseudintermedius is a pathogen of veterinary importance, as it is the major causative agent of superficial pyoderma in dogs. We present the…”
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Growth Factor Independent-1 Induced by IL-4 Regulates Th2 Cell Proliferation
Published in Immunity (Cambridge, Mass.) (01-05-2002)“…IL-4 is important in Th2 differentiation and in cell expansion. Stat6 is necessary and sufficient for both functions. Although Gata3 is critical for Th2…”
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Trophic ecology of Arapaima in Guyana: giant omnivores in Neotropical floodplains
Published in Neotropical Ichthyology (01-06-2013)“…Using stable nitrogen and carbon isotope signatures, we investigated the trophic ecology and identified potential prey fish groups supporting the giant…”
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Spatio-temporal connectivity of the aquatic microbiome associated with cyanobacterial blooms along a Great Lake riverine-lacustrine continuum
Published in Frontiers in microbiology (09-02-2023)“…Lake Erie is subject to recurring events of cyanobacterial harmful algal blooms (cHABs), but measures of nutrients and total phytoplankton biomass seem to be…”
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Deep Cyanobacteria Layers: An Overlooked Aspect of Managing Risks of Cyanobacteria
Published in Environmental science & technology (20-12-2022)“…The risk of human exposure to cyanotoxins is partially influenced by the location of toxin-producing cyanobacteria in waterbodies. Cyanotoxin production can…”
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In TH2 Cells the Il4 Gene Has a Series of Accessibility States Associated with Distinctive Probabilities of IL-4 Production
Published in Proceedings of the National Academy of Sciences - PNAS (06-08-2002)“…TH2 clones may produce very variable amounts of IL-4. Among six TH2 clones prepared from homozygous or heterozygous mice in which Gfp replaced the first exon…”
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Recovery, conservation status, and environmental effects on arapaima populations in Guyana
Published in Aquatic conservation (01-09-2021)“…Using population estimates that were made regularly between 2001 and 2013, the state of recovery of arapaima populations and their IUCN conservation status…”
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Student and faculty perceptions of effectiveness of online teaching modalities
Published in Nurse education today (01-01-2023)“…When the COVID-19 pandemic forced colleges and universities to rapidly transition from face-to-face teaching to online teaching/learning environments,…”
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