Search Results - "Watson, Chris"

A randomized trial of normothermic preservation in liver transplantation by Nasralla, David, Coussios, Constantin C., Mergental, Hynek, Akhtar, M. Zeeshan, Butler, Andrew J., Ceresa, Carlo D. L., Chiocchia, Virginia, Dutton, Susan J., García-Valdecasas, Juan Carlos, Heaton, Nigel, Imber, Charles, Jassem, Wayel, Jochmans, Ina, Karani, John, Knight, Simon R., Kocabayoglu, Peri, Malagò, Massimo, Mirza, Darius, Morris, Peter J., Pallan, Arvind, Paul, Andreas, Pavel, Mihai, Perera, M. Thamara P. R., Pirenne, Jacques, Ravikumar, Reena, Russell, Leslie, Upponi, Sara, Watson, Chris J. E., Weissenbacher, Annemarie, Ploeg, Rutger J., Friend, Peter J.

“…Liver transplantation is a highly successful treatment, but is severely limited by the shortage in donor organs. However, many potential donor organs cannot be…”
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Detection of Fe i in the atmosphere of the ultra-hot Jupiter WASP-121b, and a new likelihood-based approach for Doppler-resolved spectroscopy by Gibson, Neale P, Merritt, Stephanie, Nugroho, Stevanus K, Cubillos, Patricio E, de Mooij, Ernst J W, Mikal-Evans, Thomas, Fossati, Luca, Lothringer, Joshua, Nikolov, Nikolay, Sing, David K, Spake, Jessica J, Watson, Chris A, Wilson, Jamie

“…ABSTRACT High-resolution Doppler-resolved spectroscopy has opened up a new window into the atmospheres of both transiting and non-transiting exoplanets. Here,…”
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Diabetic Nephropathy: a Tangled Web to Unweave by Magee, Corey, Grieve, David J., Watson, Chris J., Brazil, Derek P.

“…Diabetic nephropathy (DN) is currently the leading cause of end-stage renal disease globally. Given the increasing incidence of diabetes, many experts hold the…”
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Searching for thermal inversion agents in the transmission spectrum of KELT-20b/MASCARA-2b: detection of neutral iron and ionised calcium H&K lines by Nugroho, Stevanus K, Gibson, Neale P, de Mooij, Ernst J W, Watson, Chris A, Kawahara, Hajime, Merritt, Stephanie

“…ABSTRACT We analyse the transmission spectra of KELT-20b/MASCARA-2b to search for possible thermal inversion agents. The data consist of three transits…”
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An inventory of atomic species in the atmosphere of WASP-121b using UVES high-resolution spectroscopy by Merritt, Stephanie R, Gibson, Neale P, Nugroho, Stevanus K, de Mooij, Ernst J W, Hooton, Matthew J, Lothringer, Joshua D, Matthews, Shannon M, Mikal-Evans, Thomas, Nikolov, Nikolay, Sing, David K, Watson, Chris A

“…ABSTRACT Ultrahot Jupiters (UHJs) present excellent targets for atmospheric characterization. Their hot dayside temperatures (T ≳ 2200 K) strongly suppress the…”
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Reactive oxygen species signalling in the diabetic heart: emerging prospect for therapeutic targeting by Wilson, Adam J, Gill, Eleanor K, Abudalo, Rawan A, Edgar, Kevin S, Watson, Chris J, Grieve, David J

“…Despite being first described 45 years ago, the existence of a distinct diabetic cardiomyopathy remains controversial. Nonetheless, it is widely accepted that…”
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MicroRNA signatures differentiate preserved from reduced ejection fraction heart failure by Watson, Chris J., Gupta, Shashi K., O'Connell, Eoin, Thum, Sabrina, Glezeva, Nadezhda, Fendrich, Jasmin, Gallagher, Joe, Ledwidge, Mark, Grote-Levi, Lea, McDonald, Kenneth, Thum, Thomas

“…Aims Differentiation of heart failure with reduced (HFrEF) or preserved (HFpEF) ejection fraction independent of echocardiography is challenging in the…”
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Hypoxia-induced DNA hypermethylation in human pulmonary fibroblasts is associated with Thy-1 promoter methylation and the development of a pro-fibrotic phenotype by Robinson, Claire M, Neary, Roisin, Levendale, Ashleigh, Watson, Chris J, Baugh, John A

“…Pulmonary fibrosis is a debilitating and lethal disease with no effective treatment options. Understanding the pathological processes at play will direct the…”
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Circulating biomarkers for management of cancer therapeutics-related cardiac dysfunction by Tonry, Claire, Russell-Hallinan, Adam, McCune, Claire, Collier, Patrick, Harbinson, Mark, Dixon, Lana, Watson, Chris J

“…Abstract Cancer therapeutics-related cardiac dysfunction (CTRCD) has emerged as a major cause of morbidity and mortality in cancer survivors. Effective…”
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Seroprevalence of SARS-CoV-2 antibodies in children: a prospective multicentre cohort study by Waterfield, Thomas, Watson, Chris, Moore, Rebecca, Ferris, Kathryn, Tonry, Claire, Watt, Alison, McGinn, Claire, Foster, Steven, Evans, Jennifer, Lyttle, Mark David, Ahmad, Shazaad, Ladhani, Shamez, Corr, Michael, McFetridge, Lisa, Mitchell, Hannah, Brown, Kevin, Amirthalingam, Gayatri, Maney, Julie-Ann, Christie, Sharon

“…BackgroundStudies based on molecular testing of oral/nasal swabs underestimate SARS-CoV-2 infection due to issues with test sensitivity, test timing and…”
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A Spectroscopic Thermometer: Individual Vibrational Band Spectroscopy with the Example of OH in the Atmosphere of WASP-33b by Wright, Sam O. M., Nugroho, Stevanus K., Brogi, Matteo, Gibson, Neale P., de Mooij, Ernst J. W., Waldmann, Ingo, Tennyson, Jonathan, Kawahara, Hajime, Kuzuhara, Masayuki, Hirano, Teruyuki, Kotani, Takayuki, Kawashima, Yui, Masuda, Kento, Birkby, Jayne L., Watson, Chris A., Tamura, Motohide, Zwintz, Konstanze, Harakawa, Hiroki, Kudo, Tomoyuki, Hodapp, Klaus, Jacobson, Shane, Konishi, Mihoko, Kurokawa, Takashi, Nishikawa, Jun, Omiya, Masashi, Serizawa, Takuma, Ueda, Akitoshi, Vievard, Sébastien, Yurchenko, Sergei N.

“…Abstract Individual vibrational band spectroscopy presents an opportunity to examine exoplanet atmospheres in detail, by distinguishing where the vibrational…”
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Gemini/GMOS optical transmission spectroscopy of WASP-121b: signs of variability in an ultra-hot Jupiter? by Wilson, Jamie, Gibson, Neale P, Lothringer, Joshua D, Sing, David K, Mikal-Evans, Thomas, de Mooij, Ernst J W, Nikolov, Nikolay, Watson, Chris A

“…ABSTRACT We present ground-based, spectroscopic observations of two transits of the ultra-hot Jupiter WASP-121b covering the wavelength range ≈500–950 nm using…”
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Hypoxia-induced epigenetic modifications are associated with cardiac tissue fibrosis and the development of a myofibroblast-like phenotype by Watson, Chris J, Collier, Patrick, Tea, Isaac, Neary, Roisin, Watson, Jenny A, Robinson, Claire, Phelan, Dermot, Ledwidge, Mark T, McDonald, Kenneth M, McCann, Amanda, Sharaf, Osama, Baugh, John A

“…Ischemia caused by coronary artery disease and myocardial infarction leads to aberrant ventricular remodeling and cardiac fibrosis. This occurs partly through…”
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Diabetes and complications of the heart in Sub-Saharan Africa: An urgent need for improved awareness, diagnostics and management by Glezeva, Nadezhda, Chisale, Master, McDonald, Kenneth, Ledwidge, Mark, Gallagher, Joe, Watson, Chris J.

“…•Diabetes is a growing global phenomenon particularly in low and middle income countries in Africa.•Studies have shown that diabetic cardiomyopathy is highly…”
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Fundamental control of grade‐specific colorectal cancer morphology by Src regulation of ezrin–centrosome engagement by Rainey, Lisa, Deevi, Ravi K, McClements, Jane, Khawaja, Hajrah, Watson, Chris J, Roudier, Martine, Van Schaeybroeck, Sandra, Campbell, Frederick C

“…The phenotypic spectrum of colorectal cancer (CRC) is remarkably diverse, with seemingly endless variations in cell shape, mitotic figures and multicellular…”
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Biomarker profiling for risk of future heart failure (HFpEF) development by Watson, Chris J, Gallagher, Joe, Wilkinson, Mark, Russell-Hallinan, Adam, Tea, Isaac, James, Stephanie, O'Reilly, James, O'Connell, Eoin, Zhou, Shuaiwei, Ledwidge, Mark, McDonald, Ken

“…The purpose of this study was to investigate the utility of BNP, hsTroponin-I, interleukin-6, sST2, and galectin-3 in predicting the future development of new…”
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What do patients want from a digital device that supports heart failure self-management? by McCune, Claire, McNulty, Anne, Tonry, Claire, Fitzsimons, Donna, Thompson, David R., Watson, Jenny A., Watson, Chris J., Dixon, Lana, Hill, Loreena

“…To assess patients’ needs and the factors determining their acceptance of an e-Health intervention. Purposive sample of patients with heart failure, attending…”
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Epigenetic Therapy for the Treatment of Hypertension-Induced Cardiac Hypertrophy and Fibrosis by Watson, Chris J, Horgan, Stephen, Neary, Roisin, Glezeva, Nadezhda, Tea, Isaac, Corrigan, Niamh, McDonald, Ken, Ledwidge, Mark, Baugh, John

“…The development of heart failure is associated with changes in the size, shape, and structure of the heart that has a negative impact on cardiac function…”
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FKBPL is associated with metabolic parameters and is a novel determinant of cardiovascular disease by Januszewski, Andrzej S., Watson, Chris J., O’Neill, Vikki, McDonald, Kenneth, Ledwidge, Mark, Robson, Tracy, Jenkins, Alicia J., Keech, Anthony C., McClements, Lana

“…Type 2 diabetes (T2D) is associated with increased risk of cardiovascular disease (CVD). As disturbed angiogenesis and endothelial dysfunction are strongly…”
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Targeted DNA Methylation Profiling of Human Cardiac Tissue Reveals Novel Epigenetic Traits and Gene Deregulation Across Different Heart Failure Patient Subtypes by Glezeva, Nadezhda, Moran, Bruce, Collier, Patrick, Moravec, Christine S, Phelan, Dermot, Donnellan, Eoin, Russell-Hallinan, Adam, O'Connor, Darran P, Gallagher, William M, Gallagher, Joe, McDonald, Kenneth, Ledwidge, Mark, Baugh, John, Das, Sudipto, Watson, Chris J

“…Limited knowledge exists of the extent of epigenetic alterations, such as DNA methylation, in heart failure (HF). We conducted targeted DNA methylation…”
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