Search Results - "Watsky, Eric"

Varenicline, an alpha 4 beta 2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Sustained-Release Bupropion and Placebo for Smoking Cessation: A Randomized Controlled Trial by Gonzales, David, Rennard, Stephen I, Nides, Mitchell, Oncken, Cheryl, Azoulay, Salomon, Billing, Clare B, Watsky, Eric J, Gong, Jason, Williams, Kathryn E, Reeves, Karen R

“…CONTEXT: The alpha 4 beta 2 nicotinic acetylcholine receptors (nAChRs) are linked to the reinforcing effects of nicotine and maintaining smoking behavior…”
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Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Sustained-Release Bupropion and Placebo for Smoking Cessation: A Randomized Controlled Trial by Gonzales, David, Rennard, Stephen I, Nides, Mitchell, Oncken, Cheryl, Azoulay, Salomon, Billing, Clare B, Watsky, Eric J, Gong, Jason, Williams, Kathryn E, Reeves, Karen R, Varenicline Phase 3 Study Group, for the

“…CONTEXT The α4β2 nicotinic acetylcholine receptors (nAChRs) are linked to the reinforcing effects of nicotine and maintaining smoking behavior. Varenicline, a…”
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Efficacy of Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Placebo or Sustained-Release Bupropion for Smoking Cessation: A Randomized Controlled Trial by Jorenby, Douglas E, Hays, J. Taylor, Rigotti, Nancy A, Azoulay, Salomon, Watsky, Eric J, Williams, Kathryn E, Billing, Clare B, Gong, Jason, Reeves, Karen R, Varenicline Phase 3 Study Group, for the

“…CONTEXT Varenicline, a partial agonist at the α4β2 nicotinic acetylcholine receptor, has the potential to aid smoking cessation by relieving nicotine…”
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Efficacy of Varenicline, an alpha 4 beta 2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Placebo or Sustained-Release Bupropion for Smoking Cessation: A Randomized Controlled Trial by Jorenby, Douglas E, Hays, JTaylor, Rigotti, Nancy A, Azoulay, Salomon, Watsky, Eric J, Williams, Kathryn E, Billing, Clare B, Gong, Jason, Reeves, Karen R

“…CONTEXT: Varenicline, a partial agonist at the alpha 4 beta 2 nicotinic acetylcholine receptor, has the potential to aid smoking cessation by relieving…”
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Meta-Regression Analysis of Placebo Response in Antipsychotic Trials, 1970–2010 by Agid, Ofer, Siu, Cynthia O., Potkin, Steven G., Kapur, Shitij, Watsky, Eric, Vanderburg, Douglas, Zipursky, Robert B., Remington, Gary

“…Placebo response has increased over the past few decades, and this temporal effect is explained by an increase of the number of sites per trial and by a…”
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A randomized evaluation of the effects of six antipsychotic agents on QTc, in the absence and presence of metabolic inhibition by HARRIGAN, Edmund P, MICELI, Jeffrey J, ANZIANO, Richard, WATSKY, Eric, REEVES, Karen R, CUTLER, Neal R, SRAMEK, T. John, SHIOVITZ, Thomas, MIDDLE, Michelle

“…Many drugs have been associated with QTc prolongation and, in some cases, this is augmented by concomitant administration with metabolic inhibitors. The…”
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Remission in schizophrenia: 196-week, double-blind treatment with ziprasidone vs. haloperidol by Potkin, Steven G., Weiden, Peter J., Loebel, Antony D., Warrington, Lewis E., Watsky, Eric J., Siu, Cynthia O.

“…To compare the remission rate and its time-course over 196 wk of double-blind treatment with an atypical antipsychotic, ziprasidone (80–160 mg/d given b.i.d.,…”
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36 Phase 1 clinical data for single-dose subcutaneous injection of RLYB116, a C5 blocking Affibody® molecule linked to an Albumod® albumin binding domain by Ma, Mark, Watsky, Eric

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Five-year efficacy and safety of asfotase alfa therapy for adults and adolescents with hypophosphatasia by Kishnani, Priya S., Rockman-Greenberg, Cheryl, Rauch, Frank, Bhatti, M. Tariq, Moseley, Scott, Denker, Andrew E., Watsky, Eric, Whyte, Michael P.

“…Hypophosphatasia (HPP) features low tissue-nonspecific alkaline phosphatase (TNSALP) isoenzyme activity resulting in extracellular accumulation of its…”
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Pharmacodynamics of asfotase alfa in adults with pediatric-onset hypophosphatasia by Seefried, Lothar, Kishnani, Priya S., Moseley, Scott, Denker, Andrew E., Watsky, Eric, Whyte, Michael P., Dahir, Kathryn M.

“…Hypophosphatasia (HPP) is the rare, inherited, metabolic bone disease characterized by low activity of the tissue-nonspecific isoenzyme of alkaline phosphatase…”
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The effect of tafamidis on the QTc interval in healthy subjects by Klamerus, Karen J., Watsky, Eric, Moller, Robert, Wang, Ronnie, Riley, Steve

“…Aims The transthyretin (TTR) stabilizer, tafamidis, has demonstrated efficacy and safety in the treatment of TTR familial amyloid polyneuropathy (20 mg day−1)…”
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Placebo response trajectories in short-term and long-term antipsychotic trials in schizophrenia by Potkin, Steven, Agid, Ofer, Siu, Cynthia, Watsky, Eric, Vanderburg, Douglas, Remington, Gary

“…Abstract Increasing rates of placebo response have eroded placebo-control group differences in randomized controlled trials, although the reasons for this…”
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The effect of tafamidis on the QT c interval in healthy subjects by Klamerus, Karen J., Watsky, Eric, Moller, Robert, Wang, Ronnie, Riley, Steve

“…Aims The transthyretin (TTR) stabilizer, tafamidis, has demonstrated efficacy and safety in the treatment of TTR familial amyloid polyneuropathy (20 mg day −1…”
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Results from the single-use autoinjector for self-administration of subcutaneous interferon beta-1a in patients with relapsing multiple sclerosis (MOSAIC) study by Wray, Sibyl, Armstrong, Robert, Herrman, Craig, Calkwood, Jonathan, Cascione, Mark, Watsky, Eric, Hayward, Brooke, Mercer, Brian, Dangond, Fernando

“…Patients with multiple sclerosis (MS) often receive long-term injectable therapy, and difficulties associated with self-injection can affect treatment…”
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Efficacy and safety of the novel selective nicotinic acetylcholine receptor partial agonist, varenicline, for smoking cessation by Oncken, Cheryl, Gonzales, David, Nides, Mitchell, Rennard, Stephen, Watsky, Eric, Billing, Clare B, Anziano, Richard, Reeves, Karen

“…The selective nicotinic acetylcholine receptor partial agonist, varenicline tartrate, represents a novel type of therapy for smoking cessation. This study…”
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PLACEBO RESPONSE IN ANTIPSYCHOTIC TRIALS: A SYSTEMATIC REVIEW AND META-ANALYSIS by Agid, Ofer, Potkin, Steven, Remington, Gary, Kapur, Shitij, Vanderburg, Douglas, Watsky, Eric, Siu, Cynthia

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LONGITUDINAL TRAJECTORY ANALYSIS OF PLACEBO RESPONSE: SHORT-TERM AND LONG-TERM RANDOMIZED CONTROLLED TRIALS by Potkin, Steven, Agid, Ofer, Remington, Gary, Kapur, Shitij, Watsky, Eric, Vanderburg, Douglas, Siu, Cynthia

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A Post Hoc Analysis of Negative Symptoms and Psychosocial Function in Patients With Schizophrenia: A 40-Week Randomized, Double-Blind Study of Ziprasidone Versus Haloperidol Followed by a 3-Year Double-Blind Extension Trial by STAHL, Stephen M, MALLA, Ashok, NEWCOMER, John W, POTKIN, Steven G, WEIDEN, Peter J, HARVEY, Philip D, LOEBEL, Antony, WATSKY, Eric, SIU, Cynthia O, ROMANO, Steve

“…Schizophrenia is a persistent, lifelong illness such that enduring functional improvements may only occur over the course of years [corrected].This post hoc…”
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SYMPTOMATIC AND FUNCTIONAL RECOVERY INDEX FOR NEGATIVE SYMPTOMS IN A 40-WEEK RANDOMIZED, DOUBLE-BLIND STUDY OF ZIPRASIDONE VERSUS HALOPERIDOL FOLLOWED BY A 3-YEAR DOUBLE-BLIND EXTENSION TRIAL by Stahl, Stephen M, Malla, Ashok, Newcomer, John W, Potkin, Steven G, Weiden, Peter J, Harvey, Philip, Loebel, Antony, Watsky, Eric, Vanderburg, Douglas, Siu, Cynthia, Romano, Steve

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Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial by Jorenby, Douglas E, Hays, J Taylor, Rigotti, Nancy A, Azoulay, Salomon, Watsky, Eric J, Williams, Kathryn E, Billing, Clare B, Gong, Jason, Reeves, Karen R

“…Varenicline, a partial agonist at the alpha4beta2 nicotinic acetylcholine receptor, has the potential to aid smoking cessation by relieving nicotine withdrawal…”
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