Search Results - "Watkins, John W"

All-Cause Mortality of Low Birthweight Infants in Infancy, Childhood, and Adolescence: Population Study of England and Wales by Watkins, W John, Kotecha, Sarah J, Kotecha, Sailesh

“…Low birthweight (LBW) is associated with increased mortality in infancy, but its association with mortality in later childhood and adolescence is less clear…”
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Effect of preterm birth on later FEV1: a systematic review and meta-analysis by Kotecha, Sarah J, Edwards, Martin O, Watkins, W John, Henderson, A John, Paranjothy, Shantini, Dunstan, Frank D, Kotecha, Sailesh

“…Increasing evidence suggests that preterm birth affects later lung function. We systematically reviewed the literature to determine whether percentage…”
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Safety and Efficacy of High-Flow Nasal Cannula Therapy in Preterm Infants: A Meta-analysis by Kotecha, Sarah J, Adappa, Roshan, Gupta, Nakul, Watkins, W John, Kotecha, Sailesh, Chakraborty, Mallinath

“…High-flow therapy is the most recent, and popular, mode of respiratory support in neonates. However, the evidence supporting its efficacy and safety has not…”
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Association of early and current life factors with telomere length in preterm-born children by Kotecha, Ella A, Zhang, Lei, Aboklaish, Ali, Cousins, Michael, Hart, Kylie, Kotecha, Sarah J, Watkins, W. John, Kotecha, Sailesh

“…Background Telomeres shorten after each cell division. Since preterm-born babies are delivered early and often suffer from inflammatory conditions such as…”
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Early-term birth is a risk factor for wheezing in childhood: A cross-sectional population study by Edwards, Martin O., BM, MRCPCH, Kotecha, Sarah J., BSc, SRD, Lowe, John, BSc, Richards, Louise, MSc, Watkins, W. John, PhD, Kotecha, Sailesh, PhD, FRCPCH

“…Background Early term–born (37-38 weeks' gestation) infants have increased respiratory morbidity during the neonatal period compared with full term–born…”
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Physical Activity and Sedentary Behavior in Preterm-Born 7-Year Old Children by Lowe, John, Watkins, W John, Kotecha, Sarah J, Kotecha, Sailesh

“…Previous studies of preterm-born children (<37 weeks' gestation) have demonstrated decrements in lung function, exercise capacity, and increased respiratory…”
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Similarities of metabolomic disturbances in prematurity-associated obstructive lung disease to chronic obstructive pulmonary disease by Course, Christopher W., Lewis, Philip A., Kotecha, Sarah J., Cousins, Michael, Hart, Kylie, Heesom, Kate J., Watkins, W. John, Kotecha, Sailesh

“…Prematurity-associated lung disease (PLD) is a long-term consequence of preterm-birth. Since the underlying mechanisms of PLD remain poorly characterised, we…”
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Metabolic Regulators Nampt and Sirt6 Serially Participate in the Macrophage Interferon Antiviral Cascade by Dantoft, Widad, Robertson, Kevin A, Watkins, W John, Strobl, Birgit, Ghazal, Peter

“…Molecular determinants underlying interferon (IFN)-macrophage biology can help delineate enzyme systems, pathways and mechanisms for enabling host-directed…”
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Differential association of air pollution exposure with neonatal and postneonatal mortality in England and Wales: A cohort study by Kotecha, Sarah J, Watkins, W John, Lowe, John, Grigg, Jonathan, Kotecha, Sailesh

“…Many but not all studies suggest an association between air pollution exposure and infant mortality. We sought to investigate whether pollution exposure is…”
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Effect of late preterm birth on longitudinal lung spirometry in school age children and adolescents by Kotecha, Sarah J, Watkins, W John, Paranjothy, Shantini, Dunstan, Frank D, Henderson, A John, Kotecha, Sailesh

“…Rates of preterm birth have increased in most industrialised countries but data on later lung function of late preterm births are limited. A study was…”
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Evidence of abnormality in glutathione metabolism in the airways of preterm born children with a history of bronchopulmonary dysplasia by Course, Christopher W., Lewis, Philip A., Kotecha, Sarah J., Cousins, Michael, Hart, Kylie, Heesom, Kate J., Watkins, W. John, Kotecha, Sailesh

“…Preterm-born children are at risk of long-term pulmonary deficits, including those who developed bronchopulmonary dysplasia (BPD) in infancy, however the…”
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Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity by Allen-Redpath, Keith, Aldrovandi, Maceler, Lauder, Sarah N., Gketsopoulou, Anastasia, Tyrrell, Victoria J., Slatter, David A., Andrews, Robert, Watkins, W. John, Atkinson, Georgia, McNeill, Eileen, Gilfedder, Anna, Protty, Majd, Burston, James, Johnson, Sam R. C., Rodrigues, Patricia R. S., Jones, Dylan O., Lee, Regent, Handa, Ashok, Channon, Keith, Obaji, Samya, Alvarez-Jarreta, Jorge, Krönke, Gerhard, Ackermann, Jochen, Jenkins, P. Vince, Collins, Peter W., O’Donnell, Valerie B.

“…Abdominal aortic aneurysm (AAA) is an inflammatory vascular disease with high mortality and limited treatment options. How blood lipids regulate AAA…”
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The effect of catch-up growth in the first year of life on later wheezing phenotypes by Kotecha, Sarah J, Lowe, John, Granell, Raquel, Watkins, W John, Henderson, A John, Kotecha, Sailesh

“…Although wheezing phenotypes have previously been accurately described using well-defined cohorts reporting longitudinal wheezing, early-life factors which…”
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Combination protein biomarkers predict multiple sclerosis diagnosis and outcomes by Kodosaki, Eleftheria, Watkins, W John, Loveless, Sam, Kreft, Karim L, Richards, Aidan, Anderson, Valerie, Hurler, Lisa, Robertson, Neil P, Zelek, Wioleta M, Tallantyre, Emma C

“…Establishing biomarkers to predict multiple sclerosis diagnosis and prognosis has been challenging using a single biomarker approach. We hypothesised that a…”
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Gene filtering strategies for machine learning guided biomarker discovery using neonatal sepsis RNA-seq data by Parkinson, Edward, Liberatore, Federico, Watkins, W John, Andrews, Robert, Edkins, Sarah, Hibbert, Julie, Strunk, Tobias, Currie, Andrew, Ghazal, Peter

“…Machine learning (ML) algorithms are powerful tools that are increasingly being used for sepsis biomarker discovery in RNA-Seq data. RNA-Seq datasets contain…”
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Characterizing the urinary proteome of prematurity-associated lung disease in school-aged children by Course, Christopher W, Lewis, Philip A, Kotecha, Sarah J, Cousins, Michael, Hart, Kylie, Watkins, W John, Heesom, Kate J, Kotecha, Sailesh

“…Although different phenotypes of lung disease after preterm birth have recently been described, the underlying mechanisms associated with each phenotype are…”
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Modulation of pulmonary desmosomes by inhaler therapy in preterm-born children with bronchopulmonary dysplasia by Course, Christopher W., Lewis, Philip A., Kotecha, Sarah J., Cousins, Michael, Hart, Kylie, Watkins, W. John, Heesom, Kate J., Kotecha, Sailesh

“…Despite evidence demonstrating persistent lung function deficits in preterm-born children, especially in those who had bronchopulmonary dysplasia (BPD) in…”
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Modelling predictive gender- and gestation-specific weight reference centiles for preterm infants using a population-based cohort study by Watkins, W. John, Farewell, Daniel, Banerjee, Sujoy, Nasef, Hesham, James, Anitha, Chakraborty, Mallinath

“…We aimed to model longitudinal data to create predictive growth charts for weight in preterm infants from birth till discharge, that took into account the…”
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Management of Prematurity-Associated Wheeze and Its Association with Atopy by Edwards, Martin O, Kotecha, Sarah J, Lowe, John, Richards, Louise, Watkins, W John, Kotecha, Sailesh

“…Although preterm birth is associated with respiratory morbidity in childhood, the role of family history of atopy and whether appropriate treatment has been…”
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Follow-up study of infants recruited to the randomised, placebo-controlled trial of azithromycin for the prevention of chronic lung disease of prematurity in preterm infants—study protocol for the AZTEC-FU study by Kotecha, Sarah J, Course, Christopher W, Jones, Kathryn E, Watkins, W. John, Berrington, Janet, Gillespie, David, Kotecha, Sailesh

“…Abstract Background Preterm birth, especially at less than 30 weeks’ gestation, is significantly associated with respiratory, neurodevelopmental and growth…”
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