Search Results - "Waters, Ryan"
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Encapsulation of an Enzyme Cascade within the Bacteriophage P22 Virus-Like Particle
Published in ACS chemical biology (21-02-2014)“…Developing methods for investigating coupled enzyme systems under conditions that mimic the cellular environment remains a significant challenge. Here we…”
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A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses
Published in Nature communications (22-01-2021)“…There is need for effective and affordable vaccines against SARS-CoV-2 to tackle the ongoing pandemic. In this study, we describe a protein nanoparticle…”
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Preliminary validation of direct detection of foot-and-mouth disease virus within clinical samples using reverse transcription loop-mediated isothermal amplification coupled with a simple lateral flow device for detection
Published in PloS one (28-08-2014)“…Rapid, field-based diagnostic assays are desirable tools for the control of foot-and-mouth disease (FMD). Current approaches involve either; 1) Detection of…”
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4
Natural History of Intracranial Arachnoid Cysts
Published in World neurosurgery (01-06-2019)“…Intracranial arachnoid cysts are a common incidental finding. Most of these remain asymptomatic with surgical intervention being reserved for those cysts…”
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5
The effects of interleukin-2 on immune response regulation
Published in Mathematical medicine and biology (14-03-2018)“…Abstract The immune system has many adaptive and dynamic components that are regulated to ensure appropriate, precise and rapid response to a foreign pathogen…”
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Assessment of the Welfare of Experimental Cattle and Pigs Using the Animal Welfare Assessment Grid
Published in Animals (Basel) (02-04-2021)“…The Animal Welfare Assessment Grid (AWAG) is a method for assessing quality of life, originally designed for experimental primates. This study adapts the AWAG…”
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Induced Europium Circularly Polarized Luminescence Monitors Reversible Drug Binding to Native α1‐Acid Glycoprotein
Published in ChemMedChem (03-02-2017)“…Alpha‐1‐acid glycoprotein (α1‐AGP) is an important blood plasma glycoprotein. Following an acute‐phase reaction such as stress, inflammation, burn, or…”
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Effect of Foot-and-Mouth Disease Virus Infection on the Frequency, Phenotype and Function of Circulating Dendritic Cells in Cattle
Published in PloS one (23-03-2016)“…Foot-and-mouth disease virus (FMDV) is a highly contagious virus that causes one of the most devastating diseases in cloven-hoofed animals. Disease symptoms…”
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Antibodies to the core proteins of Nairobi sheep disease virus/Ganjam virus reveal details of the distribution of the proteins in infected cells and tissues
Published in PloS one (23-04-2015)“…Nairobi sheep disease virus (NSDV; also called Ganjam virus in India) is a bunyavirus of the genus Nairovirus. It causes a haemorrhagic gastroenteritis in…”
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Detection of foot-and-mouth disease virus RNA using a closed loop-mediated isothermal amplification system
Published in Frontiers in microbiology (31-07-2024)“…Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals responsible for economic losses that amount to >$20 billion…”
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Porcine Respiratory Coronavirus as a Model for Acute Respiratory Coronavirus Disease
Published in Frontiers in immunology (28-03-2022)“…In the light of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, we have developed a porcine respiratory coronavirus (PRCV) model for…”
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Effect of mucosal adjuvant IL-1β on heterotypic immunity in a pig influenza model
Published in Frontiers in immunology (20-04-2023)“…T cell responses directed against highly conserved viral proteins contribute to the clearance of the influenza virus and confer broadly cross-reactive and…”
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Foot-and-mouth disease virus infection in the domestic dog (Canis lupus familiaris), Iran
Published in BMC veterinary research (01-02-2021)“…Foot-and-mouth disease (FMD) is a highly infectious viral disease, recognised to affect animals in the order Artiodactyla. The disease is rarely fatal in adult…”
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Enhanced sensitivity in detection of antiviral antibody responses using biotinylation of foot-and-mouth disease virus (FMDV) capsids
Published in Journal of immunological methods (01-11-2017)“…Analysis of the immune response to infection of livestock by foot-and-mouth disease virus (FMDV) is most often reported as the serum antibody response to the…”
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A Systematic Evaluation of High-Throughput Sequencing Approaches to Identify Low-Frequency Single Nucleotide Variants in Viral Populations
Published in Viruses (20-10-2020)“…High-throughput sequencing such as those provided by Illumina are an efficient way to understand sequence variation within viral populations. However,…”
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Cytokine gene polymorphisms and outcome after traumatic brain injury
Published in Journal of neurotrauma (15-10-2013)“…Clinical outcome after traumatic brain injury (TBI) is variable and cannot easily be predicted. There is increasing evidence to suggest that there may be…”
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17
Induced Europium Circularly Polarized Luminescence Monitors Reversible Drug Binding to Native α 1 -Acid Glycoprotein
Published in ChemMedChem (03-02-2017)“…Alpha-1-acid glycoprotein (α -AGP) is an important blood plasma glycoprotein. Following an acute-phase reaction such as stress, inflammation, burn, or…”
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18
Development and Evaluation of Molecular Pen-Side Assays without Prior RNA Extraction for Peste des Petits Ruminants (PPR) and Foot and Mouth Disease (FMD)
Published in Viruses (17-04-2022)“…Animal diseases such as peste des petits ruminants (PPR) and foot and mouth disease (FMD) cause significant economic losses in endemic countries and fast,…”
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Development of a High-Throughput ex-Vivo Burn Wound Model Using Porcine Skin, and Its Application to Evaluate New Approaches to Control Wound Infection
Published in Frontiers in cellular and infection microbiology (15-06-2018)“…Biofilm formation in wounds is considered a major barrier to successful treatment, and has been associated with the transition of wounds to a chronic…”
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Investigating intra-host and intra-herd sequence diversity of foot-and-mouth disease virus
Published in Infection, genetics and evolution (01-10-2016)“…Due to the poor-fidelity of the enzymes involved in RNA genome replication, foot-and-mouth disease (FMD) virus samples comprise of unique polymorphic…”
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