Search Results - "Waters, Katrina M."

Implications of Bioremediation of Polycyclic Aromatic Hydrocarbon-Contaminated Soils for Human Health and Cancer Risk by Davie-Martin, Cleo L., Stratton, Kelly G., Teeguarden, Justin G., Waters, Katrina M., Simonich, Staci L. Massey

“…Bioremediation uses soil microorganisms to degrade polycyclic aromatic hydrocarbons (PAHs) into less toxic compounds and can be performed in situ, without the…”
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How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology by Wittwehr, Clemens, Aladjov, Hristo, Ankley, Gerald, Byrne, Hugh J, de Knecht, Joop, Heinzle, Elmar, Klambauer, Günter, Landesmann, Brigitte, Luijten, Mirjam, MacKay, Cameron, Maxwell, Gavin, Meek, M E Bette, Paini, Alicia, Perkins, Edward, Sobanski, Tomasz, Villeneuve, Dan, Waters, Katrina M, Whelan, Maurice

“…Efforts are underway to transform regulatory toxicology and chemical safety assessment from a largely empirical science based on direct observation of apical…”
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Ion mobility spectrometry and the omics: Distinguishing isomers, molecular classes and contaminant ions in complex samples by Burnum-Johnson, Kristin E., Zheng, Xueyun, Dodds, James N., Ash, Jeremy, Fourches, Denis, Nicora, Carrie D., Wendler, Jason P., Metz, Thomas O., Waters, Katrina M., Jansson, Janet K., Smith, Richard D., Baker, Erin S.

“…Ion mobility spectrometry (IMS) is a widely used analytical technique providing rapid gas phase separations. IMS alone is useful, but its coupling with mass…”
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MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape by Menachery, Vineet D., Schäfer, Alexandra, Burnum-Johnson, Kristin E., Mitchell, Hugh D., Eisfeld, Amie J., Walters, Kevin B., Nicora, Carrie D., Purvine, Samuel O., Casey, Cameron P., Monroe, Matthew E., Weitz, Karl K., Stratton, Kelly G., Webb-Robertson, Bobbie-Jo M., Gralinski, Lisa E., Metz, Thomas O., Smith, Richard D., Waters, Katrina M., Sims, Amy C., Kawaoka, Yoshihiro, Baric, Ralph S.

“…Convergent evolution dictates that diverse groups of viruses will target both similar and distinct host pathways to manipulate the immune response and improve…”
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Hypergraph models of biological networks to identify genes critical to pathogenic viral response by Feng, Song, Heath, Emily, Jefferson, Brett, Joslyn, Cliff, Kvinge, Henry, Mitchell, Hugh D., Praggastis, Brenda, Eisfeld, Amie J., Sims, Amy C., Thackray, Larissa B., Fan, Shufang, Walters, Kevin B., Halfmann, Peter J., Westhoff-Smith, Danielle, Tan, Qing, Menachery, Vineet D., Sheahan, Timothy P., Cockrell, Adam S., Kocher, Jacob F., Stratton, Kelly G., Heller, Natalie C., Bramer, Lisa M., Diamond, Michael S., Baric, Ralph S., Waters, Katrina M., Kawaoka, Yoshihiro, McDermott, Jason E., Purvine, Emilie

“…Background Representing biological networks as graphs is a powerful approach to reveal underlying patterns, signatures, and critical components from…”
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Phenotypically anchored transcriptome profiling of developmental exposure to the antimicrobial agent, triclosan, reveals hepatotoxicity in embryonic zebrafish by Haggard, Derik E., Noyes, Pamela D., Waters, Katrina M., Tanguay, Robert L.

“…Triclosan (TCS) is an antimicrobial agent commonly found in a variety of personal care products and cosmetics. TCS readily enters the environment through…”
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Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework by Teeguarden, Justin G, Tan, Yu-Mei, Edwards, Stephen W, Leonard, Jeremy A, Anderson, Kim A, Corley, Richard A, Kile, Molly L, Simonich, Staci M, Stone, David, Tanguay, Robert L, Waters, Katrina M, Harper, Stacey L, Williams, David E

“…Driven by major scientific advances in analytical methods, biomonitoring, computation, and a newly articulated vision for a greater impact in public health,…”
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Gene co-expression network analysis in zebrafish reveals chemical class specific modules by Shankar, Prarthana, McClure, Ryan S, Waters, Katrina M, Tanguay, Robyn L

“…Zebrafish is a popular animal model used for high-throughput screening of chemical hazards, however, investigations of transcriptomic mechanisms of toxicity…”
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MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis by Menachery, Vineet D, Mitchell, Hugh D, Cockrell, Adam S, Gralinski, Lisa E, Yount, Jr, Boyd L, Graham, Rachel L, McAnarney, Eileen T, Douglas, Madeline G, Scobey, Trevor, Beall, Anne, Dinnon, 3rd, Kenneth, Kocher, Jacob F, Hale, Andrew E, Stratton, Kelly G, Waters, Katrina M, Baric, Ralph S

“…While dispensable for viral replication, coronavirus (CoV) accessory open reading frame (ORF) proteins often play critical roles during infection and…”
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Coupling Genome-wide Transcriptomics and Developmental Toxicity Profiles in Zebrafish to Characterize Polycyclic Aromatic Hydrocarbon (PAH) Hazard by Shankar, Prarthana, Geier, Mitra C, Truong, Lisa, McClure, Ryan S, Pande, Paritosh, Waters, Katrina M, Tanguay, Robert L

“…Polycyclic Aromatic Hydrocarbons (PAHs) are diverse environmental pollutants associated with adverse human health effects. Many studies focus on the…”
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Multi-platform ’Omics Analysis of Human Ebola Virus Disease Pathogenesis by Eisfeld, Amie J., Halfmann, Peter J., Wendler, Jason P., Kyle, Jennifer E., Burnum-Johnson, Kristin E., Peralta, Zuleyma, Maemura, Tadashi, Walters, Kevin B., Watanabe, Tokiko, Fukuyama, Satoshi, Yamashita, Makoto, Jacobs, Jon M., Kim, Young-Mo, Casey, Cameron P., Stratton, Kelly G., Webb-Robertson, Bobbie-Jo M., Gritsenko, Marina A., Monroe, Matthew E., Weitz, Karl K., Shukla, Anil K., Tian, Mingyuan, Neumann, Gabriele, Reed, Jennifer L., van Bakel, Harm, Metz, Thomas O., Smith, Richard D., Waters, Katrina M., N'jai, Alhaji, Sahr, Foday, Kawaoka, Yoshihiro

“…The pathogenesis of human Ebola virus disease (EVD) is complex. EVD is characterized by high levels of virus replication and dissemination, dysregulated immune…”
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Modeling PAH Mixture Interactions in a Human In Vitro Organotypic Respiratory Model by Colvin, Victoria C, Bramer, Lisa M, Rivera, Brianna N, Pennington, Jamie M, Waters, Katrina M, Tilton, Susan C

“…One of the most significant challenges in human health risk assessment is to evaluate hazards from exposure to environmental chemical mixtures. Polycyclic…”
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Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury by Gralinski, Lisa E, Bankhead, 3rd, Armand, Jeng, Sophia, Menachery, Vineet D, Proll, Sean, Belisle, Sarah E, Matzke, Melissa, Webb-Robertson, Bobbie-Jo M, Luna, Maria L, Shukla, Anil K, Ferris, Martin T, Bolles, Meagan, Chang, Jean, Aicher, Lauri, Waters, Katrina M, Smith, Richard D, Metz, Thomas O, Law, G Lynn, Katze, Michael G, McWeeney, Shannon, Baric, Ralph S

“…Systems biology offers considerable promise in uncovering novel pathways by which viruses and other microbial pathogens interact with host signaling and…”
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Evaluating predictive relationships between wristbands and urine for assessment of personal PAH exposure by Dixon, Holly M., Bramer, Lisa M., Scott, Richard P., Calero, Lehyla, Holmes, Darrell, Gibson, Elizabeth A., Cavalier, Haleigh M., Rohlman, Diana, Miller, Rachel L., Calafat, Antonia M., Kincl, Laurel, Waters, Katrina M., Herbstman, Julie B., Anderson, Kim A.

“…•Novel application of descriptive statistics and supervised statistical learning.•Found significant associations between PAH and OH-PAH concentrations.•Used…”
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Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses by Menachery, Vineet D, Eisfeld, Amie J, Schäfer, Alexandra, Josset, Laurence, Sims, Amy C, Proll, Sean, Fan, Shufang, Li, Chengjun, Neumann, Gabriele, Tilton, Susan C, Chang, Jean, Gralinski, Lisa E, Long, Casey, Green, Richard, Williams, Christopher M, Weiss, Jeffrey, Matzke, Melissa M, Webb-Robertson, Bobbie-Jo, Schepmoes, Athena A, Shukla, Anil K, Metz, Thomas O, Smith, Richard D, Waters, Katrina M, Katze, Michael G, Kawaoka, Yoshihiro, Baric, Ralph S

“…The broad range and diversity of interferon-stimulated genes (ISGs) function to induce an antiviral state within the host, impeding viral pathogenesis. While…”
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Transcriptomic and phenotypic profiling in developing zebrafish exposed to thyroid hormone receptor agonists by Haggard, Derik E., Noyes, Pamela D., Waters, Katrina M., Tanguay, Robert L.

“…•Transcriptomics was performed in zebrafish exposed to 25 endocrine active chemicals.•A unique transcriptional signature for thyroid receptor agonists was…”
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Relative Influence of Trans-Pacific and Regional Atmospheric Transport of PAHs in the Pacific Northwest, U.S by Lafontaine, Scott, Schrlau, Jill, Butler, Jack, Jia, Yuling, Harper, Barbara, Harris, Stuart, Bramer, Lisa M, Waters, Katrina M, Harding, Anna, Simonich, Staci L. Massey

“…The relative influences of trans-Pacific and regional atmospheric transport on measured concentrations of polycyclic aromatic hydrocarbons (PAHs), PAH…”
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Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse by Siddens, Lisbeth K., Larkin, Andrew, Krueger, Sharon K., Bradfield, Christopher A., Waters, Katrina M., Tilton, Susan C., Pereira, Cliff B., Löhr, Christiane V., Arlt, Volker M., Phillips, David H., Williams, David E., Baird, William M.

“…The polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene (BaP), was compared to dibenzo[def,p]chrysene (DBC) and combinations of three environmental PAH…”
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Impact of acute temperature and air pollution exposures on adult lung function: A panel study of asthmatics by Evoy, Richard, Kincl, Laurel, Rohlman, Diana, Bramer, Lisa M, Dixon, Holly M, Hystad, Perry, Bae, Harold, Barton, Michael, Phillips, Aaron, Miller, Rachel L, Waters, Katrina M, Herbstman, Julie B, Anderson, Kim A

“…Background Individuals with respiratory conditions, such as asthma, are particularly susceptible to adverse health effects associated with higher levels of…”
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Structurally distinct polycyclic aromatic hydrocarbons induce differential transcriptional responses in developing zebrafish by Goodale, Britton C., Tilton, Susan C., Corvi, Margaret M., Wilson, Glenn R., Janszen, Derek B., Anderson, Kim A., Waters, Katrina M., Tanguay, Robert L.

“…Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in the environment as components of fossil fuels and by-products of combustion. These multi-ring…”
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