Search Results - "Waters, J J"
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Epidemiology, Biology, and Impact of Clonal Pseudomonas aeruginosa Infections in Cystic Fibrosis
Published in Clinical microbiology reviews (01-10-2018)“…Chronic lower airway infection with is a major contributor to morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF)…”
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Pharmacokinetic and Pharmacodynamic Considerations for Drugs Binding to Alpha-1-Acid Glycoprotein
Published in Pharmaceutical research (01-02-2019)“…According to the free drug hypothesis only the unbound drug is available to act at physiological sites of action, and as such the importance of plasma protein…”
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3
Intercalant-independent transition temperature in superconducting black phosphorus
Published in Nature communications (12-04-2017)“…Research on black phosphorus has been experiencing a renaissance over the last years, after the demonstration that few-layer crystals exhibit high carrier…”
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JAK2 activation by growth hormone and other cytokines
Published in Biochemical journal (15-02-2015)“…Growth hormone (GH) and structurally related cytokines regulate a great number of physiological and pathological processes. They do this by coupling their…”
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Only in dying, life: programmed cell death during plant development
Published in Trends in plant science (01-02-2015)“…•Programmed cell death (PCD) is an integral part of plant life.•Numerous PCD instances occur during regular plant development.•Developmental PCD is tightly…”
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Impermeable barrier films and protective coatings based on reduced graphene oxide
Published in Nature communications (11-09-2014)“…Flexible barrier films preventing permeation of gases and moistures are important for many industries ranging from food to medical and from chemical to…”
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7
Genome-wide identification of bacterial plant colonization genes
Published in PLoS biology (22-09-2017)“…Diverse soil-resident bacteria can contribute to plant growth and health, but the molecular mechanisms enabling them to effectively colonize their plant hosts…”
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Skillful long-range prediction of European and North American winters
Published in Geophysical research letters (16-04-2014)“…Until recently, long‐range forecast systems showed only modest levels of skill in predicting surface winter climate around the Atlantic Basin and associated…”
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Transposable elements contribute to activation of maize genes in response to abiotic stress
Published in PLoS genetics (2015)“…Transposable elements (TEs) account for a large portion of the genome in many eukaryotic species. Despite their reputation as "junk" DNA or genomic parasites…”
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The growth hormone receptor: mechanism of activation and clinical implications
Published in Nature reviews. Endocrinology (01-09-2010)“…This Review addresses the relative roles of growth hormone and IGF 1 in mediating their biological effects, as well as the clinical outcome of inappropriate…”
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The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia
Published in Blood (14-06-2018)“…Pinometostat (EPZ-5676) is a first-in-class small-molecule inhibitor of the histone methyltransferase disrupter of telomeric silencing 1-like (DOT1L). In this…”
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Potent inhibition of DOT1L as treatment of MLL-fusion leukemia
Published in Blood (08-08-2013)“…Rearrangements of the MLL gene define a genetically distinct subset of acute leukemias with poor prognosis. Current treatment options are of limited…”
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Distinction between MOG antibody-positive and AQP4 antibody-positive NMO spectrum disorders
Published in Neurology (11-02-2014)“…OBJECTIVE:To evaluate clinical features among patients with neuromyelitis optica spectrum disorders (NMOSD) who have myelin oligodendrocyte glycoprotein (MOG)…”
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P‐PB‐11 | Implementation of a Computerized Physician Order Entry Alert for Double Dose Red Cell Orders
Published in Transfusion (Philadelphia, Pa.) (01-10-2023)Get full text
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A New Realization of SI for Organic Chemical Measurement: NIST PS1 Primary Standard for Quantitative NMR (Benzoic Acid)
Published in Analytical chemistry (Washington) (04-09-2018)“…Metrological traceability to common references supports the comparability of chemical measurement results produced by different analysts, at various times, and…”
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Dispersal Reduction: Causes, Genomic Mechanisms, and Evolutionary Consequences
Published in Trends in ecology & evolution (Amsterdam) (01-06-2020)“…Recent biological analyses suggest that reductions in dispersal ability have been key drivers of diversification across numerous lineages. We synthesise…”
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The First Year of S-CUBED: The Swift Small Magellanic Cloud Survey
Published in The Astrophysical journal (20-11-2018)“…The Swift Small Magellanic Cloud (SMC) Survey, S-CUBED, is a high-cadence shallow X-ray survey of the SMC. The survey consists of 142 tiled pointings covering…”
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A global spatial analysis reveals where marine aquaculture can benefit nature and people
Published in PloS one (09-10-2019)“…Aquaculture of bivalve shellfish and seaweed represents a global opportunity to simultaneously advance coastal ecosystem recovery and provide substantive…”
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Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 670 Drug Compounds
Published in Drug metabolism and disposition (01-07-2008)“…We present herein a compilation and trend analysis of human i.v. pharmacokinetic data on 670 drugs representing, to our knowledge, the largest publicly…”
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Muscovite dehydration melting: Reaction mechanisms, microstructures, and implications for anatexis
Published in Journal of metamorphic geology (01-01-2020)“…Dehydration melting of muscovite in metasedimentary sequences is the initially dominant mechanism of granitic melt generation in orogenic hinterlands. In dry…”
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