Search Results - "Waters, Elizabeth S."

Dynamic Changes in the Gut Microbiome at the Acute Stage of Ischemic Stroke in a Pig Model by Jeon, Julie, Lourenco, Jeferson, Kaiser, Erin E, Waters, Elizabeth S, Scheulin, Kelly M, Fang, Xi, Kinder, Holly A, Platt, Simon R, Rothrock, Jr, Michael J, Callaway, Todd R, West, Franklin D, Park, Hea Jin

“…Stroke is a major cause of death and long-term disability affecting seven million adults in the United States each year. Recently, it has been demonstrated…”
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Exploring the predictive value of lesion topology on motor function outcomes in a porcine ischemic stroke model by Scheulin, Kelly M., Jurgielewicz, Brian J., Spellicy, Samantha E., Waters, Elizabeth S., Baker, Emily W., Kinder, Holly A., Simchick, Gregory A., Sneed, Sydney E., Grimes, Janet A., Zhao, Qun, Stice, Steven L., West, Franklin D.

“…Harnessing the maximum diagnostic potential of magnetic resonance imaging (MRI) by including stroke lesion location in relation to specific structures that are…”
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Tanshinone IIA-loaded nanoparticles and neural stem cell combination therapy improves gut homeostasis and recovery in a pig ischemic stroke model by Jeon, Julie H., Kaiser, Erin E., Waters, Elizabeth S., Yang, Xueyuan, Lourenco, Jeferson M., Fagan, Madison M., Scheulin, Kelly M., Sneed, Sydney E., Shin, Soo K., Kinder, Holly A., Kumar, Anil, Platt, Simon R., Ahn, Jeongyoun, Duberstein, Kylee J., Rothrock, Michael J., Callaway, Todd R., Xie, Jin, West, Franklin D., Park, Hea Jin

“…Impaired gut homeostasis is associated with stroke often presenting with leaky gut syndrome and increased gut, brain, and systemic inflammation that further…”
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Semi-Automated Cell and Tissue Analyses Reveal Regionally Specific Morphological Alterations of Immune and Neural Cells in a Porcine Middle Cerebral Artery Occlusion Model of Stroke by Spellicy, Samantha E, Scheulin, Kelly M, Baker, Emily W, Jurgielewicz, Brian J, Kinder, Holly A, Waters, Elizabeth S, Grimes, Janet A, Stice, Steven L, West, Franklin D

“…Histopathological analysis of cellular changes in the stroked brain provides critical information pertaining to inflammation, cell death, glial scarring, and…”
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Magnetic Resonance Imaging and Gait Analysis Indicate Similar Outcomes Between Yucatan and Landrace Porcine Ischemic Stroke Models by Sneed, Sydney E, Scheulin, Kelly M, Kaiser, Erin E, Fagan, Madison M, Jurgielewicz, Brian J, Waters, Elizabeth S, Spellicy, Samantha E, Duberstein, Kylee J, Platt, Simon R, Baker, Emily W, Stice, Steven L, Kinder, Holly A, West, Franklin D

“…The Stroke Therapy Academic Industry Roundtable (STAIR) has recommended that novel therapeutics be tested in a large animal model with similar anatomy and…”
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Intracisternal administration of tanshinone IIA-loaded nanoparticles leads to reduced tissue injury and functional deficits in a porcine model of ischemic stroke by Waters, Elizabeth S., Kaiser, Erin E., Yang, Xueyuan, Fagan, Madison M., Scheulin, Kelly M., Jeon, Julie H., Shin, Soo K., Kinder, Holly A., Kumar, Anil, Platt, Simon R., Duberstein, Kylee J., Park, Hea Jin, Xie, Jin, West, Franklin D.

“…The absolute number of new stroke patients is annually increasing and there still remains only a few Food and Drug Administration (FDA) approved treatments…”
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Characterization of tissue and functional deficits in a clinically translational pig model of acute ischemic stroke by Kaiser, Erin E., Waters, Elizabeth S., Fagan, Madison M., Scheulin, Kelly M., Platt, Simon R., Jeon, Julie H., Fang, Xi, Kinder, Holly A., Shin, Soo K., Duberstein, Kylee J., Park, Hea J., West, Franklin D.

“…•Acute ischemic stroke impaired the white matter integrity of pig internal capsules.•Increased hemispheric swelling and hemorrhage resulted in notable midline…”
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Tanshinone IIA-Loaded Nanoparticle and Neural Stem Cell Therapy Enhances Recovery in a Pig Ischemic Stroke Model by Kaiser, Erin E, Waters, Elizabeth S, Yang, Xueyuan, Fagan, Madison M, Scheulin, Kelly M, Sneed, Sydney E, Cheek, Savannah R, Jeon, Julie Heejin, Shin, Soo K, Kinder, Holly A, Kumar, Anil, Platt, Simon R, Duberstein, Kylee J, Park, Hea Jin, Xie, Jin, West, Franklin D

“…Induced pluripotent stem cell-derived neural stem cells (iNSCs) are a multimodal stroke therapeutic that possess neuroprotective, regenerative, and cell…”
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Abstract P763: A Precision Medicine Approach to Intracerebral Stem Cell Transplantation Utilizing Lesion Topology in a Porcine Model of Ischemic Stroke by Scheulin, Kelly M, Jurgielewicz, Brian J, Saini, Monika, Spellicy, Samantha E, Waters, Elizabeth S, Baker, Emily W, Kinder, Holly A, Simchick, Gregory A, Sneed, Sydney E, Zhao, Qun, Stice, Steven L, West, Franklin D

“…Despite the devastating global impact of ischemic stroke, there are few Food and Drug Administration (FDA) approved treatments, none of which are capable of…”
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Abstract WMP119: Tanshinone IIa-loaded Nanoparticles And Induced Pluripotent Stem Cell-derived Neural Stem Cell Therapies Enhance Recovery In A Translational Pig Ischemic Stroke Model by Kaiser, Erin E, Waters, Elizabeth S, Yang, Xueyuan, Fagan, Madison M, Scheulin, Kelly M, Sneed, Sydney E, Jeon, Julie H, Shin, Soo K, Kinder, Holly A, Kumar, Anil, Platt, Simon R, Duberstein, Kylee J, Park, Hea Jin, Xie, Jin, West, Franklin D

“…Induced pluripotent stem cell-derived neural stem cells (iNSCs) have led to cellular and functional recovery in ischemic stroke models. However, the…”
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